A mechanism of intermediate filament disassembly regulation is proposed in which disas- sembly is regulated by the amount of proteins assembled in networks. It is Mso hypothe- sized that a delay might exist between re...A mechanism of intermediate filament disassembly regulation is proposed in which disas- sembly is regulated by the amount of proteins assembled in networks. It is Mso hypothe- sized that a delay might exist between regulation and actuM disassembly. Under realistic biological conditions of assembly and disassembly, it is shown that such a delay is harm- less and does not destabilize the organization of intermediate filaments in networks. However, for high rates of disassembly, the model predicts that delay can destabilize the organization, with the intermediate filament material oscillating between organizations mainly in networks and in nonfilamentous particles.展开更多
The definition of the globally topological equivalence of nonautonomous sys-tems is introduced, and some sufficiency theorems about the globally topological equiva-lence of two systems are given.
文摘A mechanism of intermediate filament disassembly regulation is proposed in which disas- sembly is regulated by the amount of proteins assembled in networks. It is Mso hypothe- sized that a delay might exist between regulation and actuM disassembly. Under realistic biological conditions of assembly and disassembly, it is shown that such a delay is harm- less and does not destabilize the organization of intermediate filaments in networks. However, for high rates of disassembly, the model predicts that delay can destabilize the organization, with the intermediate filament material oscillating between organizations mainly in networks and in nonfilamentous particles.
文摘The definition of the globally topological equivalence of nonautonomous sys-tems is introduced, and some sufficiency theorems about the globally topological equiva-lence of two systems are given.
