Two new type of 1,3,2-oxazaborolidines were prepared from (Is,2s)-2-amino-1-(4-nitrophenyl)-propane-1-3-diol and were used as catalyst in the asymmetric reduction of acetophenone. The influence of the reaction tempera...Two new type of 1,3,2-oxazaborolidines were prepared from (Is,2s)-2-amino-1-(4-nitrophenyl)-propane-1-3-diol and were used as catalyst in the asymmetric reduction of acetophenone. The influence of the reaction temperature as well as the effect of the structure of catalyst on the enantioselectivity was investigated. The origin of the products' configuration was discussed.展开更多
基金This work was supported by, the NNSFC.!(29972012)
文摘Two new type of 1,3,2-oxazaborolidines were prepared from (Is,2s)-2-amino-1-(4-nitrophenyl)-propane-1-3-diol and were used as catalyst in the asymmetric reduction of acetophenone. The influence of the reaction temperature as well as the effect of the structure of catalyst on the enantioselectivity was investigated. The origin of the products' configuration was discussed.
