Ultra High Molecular Weight Polyethylene(UHMWPE)has been widely used as a bearing material for artificial joint replacement over forty years.It is usually crosslinked by gamma rays irradiation before its implantation ...Ultra High Molecular Weight Polyethylene(UHMWPE)has been widely used as a bearing material for artificial joint replacement over forty years.It is usually crosslinked by gamma rays irradiation before its implantation into human body.In this study,UHMWPE and UHMWPE/nano-hydroxyapatite(n-HA)composite were prepared by vacuum hot-pressing method.The prepared materials were irradiated by gamma rays in vacuum and molten heat treated in vacuum just after irradiation.The effect of filling n-HA with gamma irradiation on tribological properties of UHMWPE was investigated by using friction and wear experimental machine(model MM-200)under deionized water lubrication.Micro-morphology of worn surface was observed by metallographic microscope.Contact angle and hardness of the materials were also measured.The results show that contact angle and hardness are changed by filling n-HA and gamma irradiation.Friction coefficient and wear rate under deionized water lubrication are reduced by filling n-HA.While friction coefficient is increased and wear rate is reduced significantly by gamma irradiation.The worn surface of unfilled material is mainly characterized as adhesive wear and abrasive wear,and that of n-HA filled material is mainly characterized as abrasive wear.After gamma irradiation,the degrees of adhesive and abrasive wear for unfilled material and abrasive wear of n-HA filled material are significantly reduced.Unfilled and filled materials after irradiation are mainly shown as slight fatigue wear.The results indicate that UHMWPE and UHMWPE/n-HA irradiated at the dose of 150 kGy can be used as bearing materials in artificial joints for its excellent wear resistance compared to original UHMWPE.展开更多
背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能。目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述。方法:由第一作者应用计算机检索Pub...背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能。目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述。方法:由第一作者应用计算机检索PubMed数据库1992年1月至2012年10月及中国期刊网全文数据库1994年1月至2012年12月有关四肢恶性骨肿瘤保肢治疗的文章,英文检索词为"malignant bone tumor,salvage treatment,allograft bone graft,prosthesis and microwave",中文检索词为"恶性骨肿瘤,保肢治疗,大段异体骨,肿瘤假体,微波灭活治疗"。排除重复性研究及Meta分析,共保留31篇文献进行综述。结果与结论:①对于四肢特别是关节周围的恶性骨肿瘤,大多采用人工关节置换、大段同种异体骨移植以及微波灭活治疗。②大段同种异体骨移植后并发症发生率较高,微波灭活治疗技术有新的进展,进一步的研究仍在进行当中。③瘤段骨灭活再植以及乙醇灭活治疗多适用于基层医院。展开更多
目的探讨宝石能谱CT（GSICT）在骨科患者术后检查中的应用效果,比较该方法与常规CT扫描的图像差异。方法选取2014年5月~2015年3月于我院骨科进行治疗的32例患者,其中20例行骨折金属固定术,12例行人工关节固定术,均对其行GSICT扫描。采用...目的探讨宝石能谱CT（GSICT）在骨科患者术后检查中的应用效果,比较该方法与常规CT扫描的图像差异。方法选取2014年5月~2015年3月于我院骨科进行治疗的32例患者,其中20例行骨折金属固定术,12例行人工关节固定术,均对其行GSICT扫描。采用GSIViewer软件分析扫描结果,并对图像进行三维重组及金属伪影去除,与常规CT扫描图像进行对比。结果与常规CT扫描图像相比,GSICT成像质量明显较高,金属伪影明显减少,可清晰呈现骨折复位、人工关节以及内固定术的修复效果。结论在高的ke V区,GSICT扫描可有效减少射线束硬化伪影以及金属植入物伪影,100~140 ke V为其成像最佳区间。在术后细微结构的成像时,充分利用GSICT的合理区间可提高成像质量。展开更多
Study on surface features of wear particles generated in wear process provides an insight into the progress of material failure of artificial joints. It is very important to quantify the surface features of wear parti...Study on surface features of wear particles generated in wear process provides an insight into the progress of material failure of artificial joints. It is very important to quantify the surface features of wear particles in three dimensions. In this study, a new approach using atomic force microscopy was proposed to carry out 3D numerical surface characterization of wear debris generated from artificial joints. Atomic force microscopy combined with image processing techniques was used to acquire appropriate 3D images of wear debris. Computerized image analysis techniques were then used to quantify surface texture features of wear debris such as surface roughness parameters and surface texture index. The method developed from the present study was found to be feasible to quantity the surface characterization of nanoand micro-sized wear debris generated from artificial joints.展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 50575106)High Technology Project of Jiangsu Province, P. R. China (Grant No. BG2007046)
文摘Ultra High Molecular Weight Polyethylene(UHMWPE)has been widely used as a bearing material for artificial joint replacement over forty years.It is usually crosslinked by gamma rays irradiation before its implantation into human body.In this study,UHMWPE and UHMWPE/nano-hydroxyapatite(n-HA)composite were prepared by vacuum hot-pressing method.The prepared materials were irradiated by gamma rays in vacuum and molten heat treated in vacuum just after irradiation.The effect of filling n-HA with gamma irradiation on tribological properties of UHMWPE was investigated by using friction and wear experimental machine(model MM-200)under deionized water lubrication.Micro-morphology of worn surface was observed by metallographic microscope.Contact angle and hardness of the materials were also measured.The results show that contact angle and hardness are changed by filling n-HA and gamma irradiation.Friction coefficient and wear rate under deionized water lubrication are reduced by filling n-HA.While friction coefficient is increased and wear rate is reduced significantly by gamma irradiation.The worn surface of unfilled material is mainly characterized as adhesive wear and abrasive wear,and that of n-HA filled material is mainly characterized as abrasive wear.After gamma irradiation,the degrees of adhesive and abrasive wear for unfilled material and abrasive wear of n-HA filled material are significantly reduced.Unfilled and filled materials after irradiation are mainly shown as slight fatigue wear.The results indicate that UHMWPE and UHMWPE/n-HA irradiated at the dose of 150 kGy can be used as bearing materials in artificial joints for its excellent wear resistance compared to original UHMWPE.
文摘背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能。目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述。方法:由第一作者应用计算机检索PubMed数据库1992年1月至2012年10月及中国期刊网全文数据库1994年1月至2012年12月有关四肢恶性骨肿瘤保肢治疗的文章,英文检索词为"malignant bone tumor,salvage treatment,allograft bone graft,prosthesis and microwave",中文检索词为"恶性骨肿瘤,保肢治疗,大段异体骨,肿瘤假体,微波灭活治疗"。排除重复性研究及Meta分析,共保留31篇文献进行综述。结果与结论:①对于四肢特别是关节周围的恶性骨肿瘤,大多采用人工关节置换、大段同种异体骨移植以及微波灭活治疗。②大段同种异体骨移植后并发症发生率较高,微波灭活治疗技术有新的进展,进一步的研究仍在进行当中。③瘤段骨灭活再植以及乙醇灭活治疗多适用于基层医院。
文摘目的探讨宝石能谱CT（GSICT）在骨科患者术后检查中的应用效果,比较该方法与常规CT扫描的图像差异。方法选取2014年5月~2015年3月于我院骨科进行治疗的32例患者,其中20例行骨折金属固定术,12例行人工关节固定术,均对其行GSICT扫描。采用GSIViewer软件分析扫描结果,并对图像进行三维重组及金属伪影去除,与常规CT扫描图像进行对比。结果与常规CT扫描图像相比,GSICT成像质量明显较高,金属伪影明显减少,可清晰呈现骨折复位、人工关节以及内固定术的修复效果。结论在高的ke V区,GSICT扫描可有效减少射线束硬化伪影以及金属植入物伪影,100~140 ke V为其成像最佳区间。在术后细微结构的成像时,充分利用GSICT的合理区间可提高成像质量。
基金Supported by UK Royal Society K C Wong Fellowship and National Natural Science Foundation of China (Grant No. 50705070)
文摘Study on surface features of wear particles generated in wear process provides an insight into the progress of material failure of artificial joints. It is very important to quantify the surface features of wear particles in three dimensions. In this study, a new approach using atomic force microscopy was proposed to carry out 3D numerical surface characterization of wear debris generated from artificial joints. Atomic force microscopy combined with image processing techniques was used to acquire appropriate 3D images of wear debris. Computerized image analysis techniques were then used to quantify surface texture features of wear debris such as surface roughness parameters and surface texture index. The method developed from the present study was found to be feasible to quantity the surface characterization of nanoand micro-sized wear debris generated from artificial joints.
