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囊性肝包虫囊肿周围肝内管道的病理解剖学观察 被引量:8
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作者 杨宏强 王菊 +5 位作者 李江 马少波 卞志远 赵瑾 张示杰 陈孝平 《中国人兽共患病学报》 CAS CSCD 北大核心 2012年第4期371-374,共4页
目的探讨囊性肝包虫外囊及囊肿周围肝内血管、胆管的病理解剖学改变及对肝组织的影响。方法取42例人肝包虫手术切除标本和5例正常人肝组织,制备外囊及其周围肝内血管、胆管和其周围组织大体病理标本及组织切片,运用常规HE染色、Masson... 目的探讨囊性肝包虫外囊及囊肿周围肝内血管、胆管的病理解剖学改变及对肝组织的影响。方法取42例人肝包虫手术切除标本和5例正常人肝组织,制备外囊及其周围肝内血管、胆管和其周围组织大体病理标本及组织切片,运用常规HE染色、Masson染色及免疫组化染色观察其病理变化。结果肝包虫周围Glisson系统内的血管及胆管呈树枝状的包绕、附着于外囊表面,失去原有的解剖位置,其所属肝组织消失,其远端管腔渐闭锁。经HE、Masson染色、Actin免疫组化观察囊性肝包虫外囊周围肝内管道的管壁发生明显纤维化,VEGF免疫组化结果示:外囊周围可见增生的小胆管和血管。结论囊型肝包虫在膨胀性生长过程中,长期挤压周围肝内管道,造成肝内管道解剖位置、结构发生改变,其病理学改变导致局部组织缺血缺氧,是引起肝包虫囊肿周围的肝组织萎缩、变性、坏死至消失原因之一。 展开更多
关键词 囊型肝包虫病 肝内管道 病理解剖学
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人工感染猪附红细胞体病的病理组织学研究 被引量:7
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作者 尤立娜 巴彩凤 +5 位作者 冯会权 李慧平 王凯 林小丰 廉长红 石蕾 《中国畜牧兽医》 CAS 2008年第6期78-80,共3页
为观察昆明小鼠人工感染猪附红细胞体后的病理组织学变化。用常规病理学方法,对6只腹腔注射感染猪附红细胞体的小鼠进行病理解剖学和病理组织学研究,光镜下观察并描述小鼠红细胞感染附红细胞体后的形态变化。剖检可见主要器官和皮下瘀血... 为观察昆明小鼠人工感染猪附红细胞体后的病理组织学变化。用常规病理学方法,对6只腹腔注射感染猪附红细胞体的小鼠进行病理解剖学和病理组织学研究,光镜下观察并描述小鼠红细胞感染附红细胞体后的形态变化。剖检可见主要器官和皮下瘀血,胸腹部皮下脂肪黄染,病理组织学变化的主要特征是心、肝、脾、肺、肾等主要脏器实质细胞变性、坏死,毛细血管扩张充血、出血,脾窦内含铁血黄素沉着。结果表明,猪附红细胞体感染小鼠模型的成功建立,镜下红细胞的形态特征及主要器官剖检和病理组织学变化与文献报道的猪附红细胞致病特征基本吻合,存在的差异可能与不同地域猪附红细胞体病原株致病性有关。 展开更多
关键词 小鼠 猪附红细胞体 病理解剖学 病理组织学
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Pathological and Etiological Aspects of Nephrotic Syndrome at the Niamey General Reference Hospital
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作者 Djibrilla Gani Salamatou Amadou Niaouro Oumarou Ali Diallo 《Open Journal of Nephrology》 2024年第3期340-349,共10页
Introduction: Studies have been conducted on nephrotic syndrome in Niger. The study aimed to determine the histological and etiological aspects of nephrotic syndrome. Patients and Method: This was a retrospective stud... Introduction: Studies have been conducted on nephrotic syndrome in Niger. The study aimed to determine the histological and etiological aspects of nephrotic syndrome. Patients and Method: This was a retrospective study from February 1st, 2018 to January 31st, 2024. All patients with nephrotic syndrome who underwent renal biopsy were included. Samples were analyzed at the anatomy-cytology pathology laboratory of the Faculty of Medicine in Dakar (Senegal). The variables studied included clinical, biological, histological and etiological characteristics. Data were analyzed using Excel 2013 and Epi-info 7.2.0 software. Results: The study included 119 patients with nephrotic syndrome. Prevalence of nephrotic syndrome was 11.24%. The male-to-female ratio was 2.25:1. The mean age at diagnosis was between 34.5 ± 18.84 years. Edema was the reason for admission in 40.34% of cases. The nephrotic syndrome was impure in 63.86% of cases. Nine histological lesions were identified. Focal and segmental glomerulosclerosis (40.09%), minimal change disease (23.53%), membranous nephropathy (13.45%), diabetic nephropathy (10.92%), membranous proliferative glomerulonephritis (3.36%), acute glomerulonephritis (3.36%), glomerular thrombotic microangiopathy (2.52%), non-IgA mesengial proliferative glomerulonephritis (1.68%) and amyloidosis (0.84%). Nephrotic syndrome was primary in 57.98% of cases. Secondary etiologies were dominated by diabetes (11.76%), followed by hepatitis B virus (9.24%), lupus, lymphoma, malaria, syphilis, cryoglobulinemia, sickle cell disease and HIV. Conclusion: Future studies should investigate the causes of glomerulopathy secondary to chronic tubulointerstitial lesions. 展开更多
关键词 Nephrotic Syndrome anatomopathology Niamey General Reference Hospital
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Clinical and Anatomo-Pathological Study of Digestive Polyps at Point G Teaching Hospital
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作者 Sanra Déborah Sanogo Marcelle Paule Tayue +10 位作者 Ganda Soumaré Ouatou Mallé Abdoulaye Maiga Luc Sidibé Hourouma Sow Kadiatou Samaké Moussa Y. Dicko Abdoulaye Diarra Ilias Guindo Bakarou Kamaté Cheickh B. Traoré 《Open Journal of Gastroenterology》 2023年第3期111-116,共6页
Introduction: The aim of our study was to describe the aspects clinical and pathology of digestive polyps. Methods: This was a descriptive and analytical study with retrospective and prospective collection from Januar... Introduction: The aim of our study was to describe the aspects clinical and pathology of digestive polyps. Methods: This was a descriptive and analytical study with retrospective and prospective collection from January 2014 to September 2020, i.e. a duration of 72 months. Our study focused on all cases of non-cancerous digestive pathologies. The data were collected from registers, medical files and reports from the anatomy and pathological cytology department of the Point G University Hospital. All of this data was entered on an individual survey form. This sheet includes demographic data, qualitative and quantitative variables. Results: We conducted a study of 131 cases of digestive polyps. The frequency of digestive polyps was 3.65%. The mean age of our patients was 44.6 ± 21 years with extremes of 2 years and 79 years, with a male predominance and a sex ratio of 1.01. The biopsy was the type of sample most represented in 77.1%. The digestive polyps were located in stomach in 37.4%;the colon in 27.5% then the rectum 21.4%. The polyp sessile accounted for 65.6%. Histological examination revealed that adenomatous polyps were predominant in 77% of cases, followed by juvenile polyps in 9.2%, then hyperplastic polyps in 6.2%. Low grade dysplasia was found in adenomatous polyps in 61.53% and high grade found in 38.4%. Gastritis due to Helicobacter pylori (Hp) was found in 16% of cases. Conclusion: Digestive polyps are common in the general population. The prognosis is linked to the risk of neoplastic degeneration of adenomas. 展开更多
关键词 Digestive Polyps CLINICAL anatomopathology
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Digestive Tuberculosis in Madagascar: Histopathological Aspects
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作者 Nomenjanahary Lalaina Rabarison Manoahasina Ranaliarinosy +1 位作者 Rakotonaivo Mamisoa Judicaël Randrianjafisamindrakotroka Nantenaina Soa 《Open Journal of Pathology》 2023年第4期229-234,共6页
Tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis complex. This illness is a major public health challenge in Madagascar and around the world. The disease can develop in the lungs an... Tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis complex. This illness is a major public health challenge in Madagascar and around the world. The disease can develop in the lungs and other organs. Digestive tuberculosis is rare, accounting for 10% of extrapulmonary forms. Symptoms are not specific. Diagnosis is based on anatomical pathology examination. The purpose of this study is to determine the epidemiological and anatomopathological characteristics of abdominal tuberculosis. Our study was a retrospective, descriptive study conducted at the Pathological Anatomy and Cytology Unit of the University Hospital Center of Joseph Ravoahangy Andrianavalona over a 10-year period from January 1, 2012 to December 31, 2021. Digestive localization accounted for 17 cases, which are 1.85% of extra-pulmonary localizations. The mean age of patients was 33 years with extremes of 9 and 66 years. The sex ratio was 4.67. Pain was the main symptom, accounting for 76.47% of cases. Histological aspects were caseo-follicular in 82.35% (n = 14) of cases, follicular in 11.76% (n = 2) and caseous in 5.89% (n = 1). Patients were treated with isoniazid, rifampicin, pyrazinamide, and ethambutol. Surgery has sometimes been required. Tuberculosis is a public health problem in Madagascar. Digestive localization of the disease is mainly observed in young adults especially among men. Clinical signs are not specific, and diagnosis is based on anatomopathology. Treatment is medical but sometimes surgery may be necessary. 展开更多
关键词 Digestive Tuberculosis anatomopathology Madagascar
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Fracture of the Humeral Palette in Adult Patient: Therapeutic and Evolutive Aspect at Gabriel Touré Hospital: About 35 Cases
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作者 Mahamadou Diallo Abdoul Kadri Moussa +10 位作者 Kalifa Coulibaly Layes Touré Mahamadou Dama Mamadou Bassirou Traoré Cheick Oumar Sanogo Terna Traoré Famakan Doumbia Mamadou Diallo Amadou Maiga Adégné Pierre Togo Tiéman Coulibaly 《Surgical Science》 2023年第4期271-276,共6页
Introduction: Fractures of the humeral pallet occur between the distal insertion of the anterior brachial muscle and the joint space of the elbow. It represents 2% of all elbow fractures. These lower humeral fractures... Introduction: Fractures of the humeral pallet occur between the distal insertion of the anterior brachial muscle and the joint space of the elbow. It represents 2% of all elbow fractures. These lower humeral fractures present a therapeutic challenge to trauma. These fractures are in the majority of joint cases and can be accompanied by loss of substance, which makes their functional prognosis random despite the application of the main therapeutic principles: exact reduction with possible bone graft;stable osteosynthesis, usually allowing early rehabilitation. This work focused on identifying therapeutic aspects and assessing treatment outcomes. Material and Methods: This was a descriptive cross-sectional study of patients with a fracture of the humeral palette from January 2015 to December 2019 at the Orthopaedic Trauma Department CHU Gabriel Touré Bamako. Results: We collected 35 cases of fractures of the humeral palette. The average age was 39.25 years with extremes of 22 and 74 years. The male gender predominated (71.4%) with a sex ratio of 2.5. Etiologies were dominated by falls with 19 cases (54.3%) and stroke with 13 cases (37.1%). The standard X-ray of the face and profile of the elbow was performed in all our patients. The most frequent types of anatomoradiology were supra condylar fractures type A in 16 cases (45.7%), supra and inter condylar fractures type C in 15 cases (42.9%);4 cases of uni condylar fractures type B (11.4%). Associated lesions were observed in 42.85%. Surgical treatment was performed in 80% of cases. Complications were dominated by elbow stiffness in 18 cases (51.42%), secondary displacement in 5 cases (14.28%), ossifications in 4 cases (11.42%). At an average decrease of 3.2 years our results were considered good in 45.7%. Conclusion: Fractures of the humeral palette are relatively common with associated lesions. The complexity of the fracture with associated lesions makes treatment difficult with unpredictable evolution. 展开更多
关键词 FRACTURE Humeral Palette anatomopathology Treatment Evolution Bamako MALI
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Epidemiological Aspects and Anatomopathological of Ear Nose and Throat (ENT) and Cervico-Facial (CF) Cancers at the Military Hospital of Nouakchott
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作者 Brahim Moulaye El Hassen Edde Dih Haimedah Moulay Ahmed Moulay Hachem 《Health》 2021年第10期1091-1096,共6页
This retrospective study, the first of its kind in Mauritania, was carried out at the military hospital of Nouakchott. We sought to approximate the epidemio-logical, anatomopathological profile of Ear, Nose and Throat... This retrospective study, the first of its kind in Mauritania, was carried out at the military hospital of Nouakchott. We sought to approximate the epidemio-logical, anatomopathological profile of Ear, Nose and Throat (ENT) and cervico-facial (CF) cancers in Mauritania. Over a period of two years, from January 1, 2019 to December 31, 2020, we noted 36 histologically confirmed cases, they represented 15.47% of all patients consulted in ENT and CF cancers affected the age group between 25 and 70 years, the age group most affected was that of 50 and 59 years, with 33.33% of cases. More affected in the proportion of 2 men to women, which can be explained by the risk factors mainly found in men, including smoking. First rank was cancers of the upper aero-digestive tract, the pharyngolarynx in head. Histologically, ENT and CF cancers were dominated by squamous cell carcinomas 78%, well ahead of papillary carcinomas 8% and vesicular thyroid carcinomas 5%, UCNTs, adenosquamous carcinomas and lymphomas each represented 3%. 展开更多
关键词 anatomopathological ENT CANCERS Cervico-Facial Military Hospital MAURITANIA
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