目的:通过观察宫颈粘连患者治疗前后血清及子宫内膜中基质金属蛋白酶抑制因子-1(tissue inhibitor of metalloproteinase-1,TIMP-1)的变化,探讨中药补肾活血周期治疗在宫腔镜术后再粘连预防中的作用机制。方法:100例宫腔粘连患者,按随...目的:通过观察宫颈粘连患者治疗前后血清及子宫内膜中基质金属蛋白酶抑制因子-1(tissue inhibitor of metalloproteinase-1,TIMP-1)的变化,探讨中药补肾活血周期治疗在宫腔镜术后再粘连预防中的作用机制。方法:100例宫腔粘连患者,按随机单盲法分为中药组(50例)和对照组(50例),2组均行宫腔镜下宫腔粘连分解术(transcervical resection of adhensions,TCRA)。术后中药组用中药补肾活血周期联合西药人工周期治疗,对照组单纯用西药人工周期治疗,用药3个月,再次进行宫腔镜检查。采用ELISA法和免疫组织化学S-P法检测治疗前后血清及子宫内膜中TIMP-1的表达。结果:治疗后2组患者粘连评分均下降(P<0.05),2组比较,差异有统计学意义(P<0.05);治疗后2组血清及子宫内膜中TIMP-1表达均降低(P<0.05),2组比较,差异均有统计学意义(P<0.05)。结论:中药补肾活血周期治疗能有效预防宫腔粘连术后再粘连,其机制与抑制TIMP-1的过度表达有关。展开更多
We have performed sequential studies on new types of soft rubber for their application as artificial skin in robots and haptic sensors. Based on a proposed electrolytic polymerization method and novel adhesion techniq...We have performed sequential studies on new types of soft rubber for their application as artificial skin in robots and haptic sensors. Based on a proposed electrolytic polymerization method and novel adhesion technique for rubber and a metal that utilizes a metal complex hydrate, we have developed an MCF rubber sensor. This sensor uses a magnetic compound fluid (MCF), natural rubber (NR-latex) or chloroprene rubber latex (CR-latex), and requires the application of a magnetic field. The potential application of the developed sensor in various engineering scenarios and our daily lives is significant. In this regard, we investigated the effects of γ-irradiation, infrared radiation, microwaves, and a thermal source on the MCF rubber sensor. We established that the MCF rubber is effective enough to be used for power generation of broadband electro-magnetic waves from γ-rays to microwaves, including the range of the solar spectrum, which is the typical characteristic obtained in the present investigation. The remarkable attribute is that the MCF rubber sensor dose is not degraded by γ-irradiation. We also demonstrated the effectiveness of the MCF rubber sensor in energy harvesting.展开更多
文摘目的:通过观察宫颈粘连患者治疗前后血清及子宫内膜中基质金属蛋白酶抑制因子-1(tissue inhibitor of metalloproteinase-1,TIMP-1)的变化,探讨中药补肾活血周期治疗在宫腔镜术后再粘连预防中的作用机制。方法:100例宫腔粘连患者,按随机单盲法分为中药组(50例)和对照组(50例),2组均行宫腔镜下宫腔粘连分解术(transcervical resection of adhensions,TCRA)。术后中药组用中药补肾活血周期联合西药人工周期治疗,对照组单纯用西药人工周期治疗,用药3个月,再次进行宫腔镜检查。采用ELISA法和免疫组织化学S-P法检测治疗前后血清及子宫内膜中TIMP-1的表达。结果:治疗后2组患者粘连评分均下降(P<0.05),2组比较,差异有统计学意义(P<0.05);治疗后2组血清及子宫内膜中TIMP-1表达均降低(P<0.05),2组比较,差异均有统计学意义(P<0.05)。结论:中药补肾活血周期治疗能有效预防宫腔粘连术后再粘连,其机制与抑制TIMP-1的过度表达有关。
文摘We have performed sequential studies on new types of soft rubber for their application as artificial skin in robots and haptic sensors. Based on a proposed electrolytic polymerization method and novel adhesion technique for rubber and a metal that utilizes a metal complex hydrate, we have developed an MCF rubber sensor. This sensor uses a magnetic compound fluid (MCF), natural rubber (NR-latex) or chloroprene rubber latex (CR-latex), and requires the application of a magnetic field. The potential application of the developed sensor in various engineering scenarios and our daily lives is significant. In this regard, we investigated the effects of γ-irradiation, infrared radiation, microwaves, and a thermal source on the MCF rubber sensor. We established that the MCF rubber is effective enough to be used for power generation of broadband electro-magnetic waves from γ-rays to microwaves, including the range of the solar spectrum, which is the typical characteristic obtained in the present investigation. The remarkable attribute is that the MCF rubber sensor dose is not degraded by γ-irradiation. We also demonstrated the effectiveness of the MCF rubber sensor in energy harvesting.