BACKGROUND A Bochdalek hernia(BH)is a congenital diaphragmatic hernia that often develops in the neonatal period.BH typically occurs on the left side of the diaphragm.A right-sided BH in an adult is rare.CASE SUMMARY ...BACKGROUND A Bochdalek hernia(BH)is a congenital diaphragmatic hernia that often develops in the neonatal period.BH typically occurs on the left side of the diaphragm.A right-sided BH in an adult is rare.CASE SUMMARY A 45-year-old man was referred to our hospital because of an abnormal shadow seen on chest radiography during a medical check-up.A chest radiograph showed elevation of the right hemidiaphragm.Computed tomography showed prolapse of multiple intraabdominal organs into the right thoracic cavity,corresponding to a right-sided BH.The herniated contents included the stomach,transverse colon,and left lobe of the liver.The left lobe of the liver was enlarged,particularly the medial segment.Laparoscopic surgery was performed.However,the left lobe of the liver was completely trapped in the thoracic cavity.Therefore,thoracoscopic manipulation had to be performed to return the liver to the abdominal cavity.The hernia was repaired with interrupted nonabsorbable sutures and reinforced with mesh.CONCLUSION Combined laparoscopic and thoracoscopic surgery was successfully performed for right-sided BH with massive liver prolapse and abnormal liver morphology.展开更多
Aberrant sperm protamination is linked to sperm dysmorphology and nuclear chromatin condensation.Yet,its effects on sperm cytoplasmic maturation remain largely unexplored.The relationships of protamines,sperm morpholo...Aberrant sperm protamination is linked to sperm dysmorphology and nuclear chromatin condensation.Yet,its effects on sperm cytoplasmic maturation remain largely unexplored.The relationships of protamines,sperm morphology,DNA damage,and cytoplasmic remodeling were illustrated in this study to provide fresh perspectives on the mechanisms of male infertility.A total of 205 infertile males were allocated into 5 groups according to the percentage of spermatozoa exhibiting abnormal morphology within their samples.Sperm concentration,motility,abnormal sperm morphology,cytoplasmic droplets(CDs),and excess residual cytoplasm(ERC)were analyzed according to the World Health Organization manual(2010).Sperm nuclear vacuoles(NVs)were determined by propidium iodide(PI)staining.Sperm protamine expressions(P1 and P2)were detected by western blot.DNA damage was measured by acridine orange test(AOT)to calculate the proportion of sperm with single-strand DNA breaks(SSBs).Our data showed that sperm concentration and motility in infertile males significantly decreased with the severity of abnormal sperm morphology(both P<0.01).P1 level,P1/P2 ratio,and SSB rate increased with the severity of sperm dysmorphology,whilst the P2 level decreased(all P<O.01).NVs,CDs,and ERC were more common in males with sperm dysmorphology and positively correlated with the SSB rate(all P<O.01).The relationships between the SSB rate and the P1/P2 ratio were also significant(P<0.01).Aberrant protamination may cause sperm dysmorphology and compromise male fertility by impairing sperm's nucleus and cytoplasm maturation,with the P1/P2 ratio potentially serving as a valuable indicator of sperm quality and male fertility.展开更多
Current methodologies for cleaning wind power anomaly data exhibit limited capabilities in identifying abnormal data within extensive datasets and struggle to accommodate the considerable variability and intricacy of ...Current methodologies for cleaning wind power anomaly data exhibit limited capabilities in identifying abnormal data within extensive datasets and struggle to accommodate the considerable variability and intricacy of wind farm data.Consequently,a method for cleaning wind power anomaly data by combining image processing with community detection algorithms(CWPAD-IPCDA)is proposed.To precisely identify and initially clean anomalous data,wind power curve(WPC)images are converted into graph structures,which employ the Louvain community recognition algorithm and graph-theoretic methods for community detection and segmentation.Furthermore,the mathematical morphology operation(MMO)determines the main part of the initially cleaned wind power curve images and maps them back to the normal wind power points to complete the final cleaning.The CWPAD-IPCDA method was applied to clean datasets from 25 wind turbines(WTs)in two wind farms in northwest China to validate its feasibility.A comparison was conducted using density-based spatial clustering of applications with noise(DBSCAN)algorithm,an improved isolation forest algorithm,and an image-based(IB)algorithm.The experimental results demonstrate that the CWPAD-IPCDA method surpasses the other three algorithms,achieving an approximately 7.23%higher average data cleaning rate.The mean value of the sum of the squared errors(SSE)of the dataset after cleaning is approximately 6.887 lower than that of the other algorithms.Moreover,the mean of overall accuracy,as measured by the F1-score,exceeds that of the other methods by approximately 10.49%;this indicates that the CWPAD-IPCDA method is more conducive to improving the accuracy and reliability of wind power curve modeling and wind farm power forecasting.展开更多
文摘BACKGROUND A Bochdalek hernia(BH)is a congenital diaphragmatic hernia that often develops in the neonatal period.BH typically occurs on the left side of the diaphragm.A right-sided BH in an adult is rare.CASE SUMMARY A 45-year-old man was referred to our hospital because of an abnormal shadow seen on chest radiography during a medical check-up.A chest radiograph showed elevation of the right hemidiaphragm.Computed tomography showed prolapse of multiple intraabdominal organs into the right thoracic cavity,corresponding to a right-sided BH.The herniated contents included the stomach,transverse colon,and left lobe of the liver.The left lobe of the liver was enlarged,particularly the medial segment.Laparoscopic surgery was performed.However,the left lobe of the liver was completely trapped in the thoracic cavity.Therefore,thoracoscopic manipulation had to be performed to return the liver to the abdominal cavity.The hernia was repaired with interrupted nonabsorbable sutures and reinforced with mesh.CONCLUSION Combined laparoscopic and thoracoscopic surgery was successfully performed for right-sided BH with massive liver prolapse and abnormal liver morphology.
文摘Aberrant sperm protamination is linked to sperm dysmorphology and nuclear chromatin condensation.Yet,its effects on sperm cytoplasmic maturation remain largely unexplored.The relationships of protamines,sperm morphology,DNA damage,and cytoplasmic remodeling were illustrated in this study to provide fresh perspectives on the mechanisms of male infertility.A total of 205 infertile males were allocated into 5 groups according to the percentage of spermatozoa exhibiting abnormal morphology within their samples.Sperm concentration,motility,abnormal sperm morphology,cytoplasmic droplets(CDs),and excess residual cytoplasm(ERC)were analyzed according to the World Health Organization manual(2010).Sperm nuclear vacuoles(NVs)were determined by propidium iodide(PI)staining.Sperm protamine expressions(P1 and P2)were detected by western blot.DNA damage was measured by acridine orange test(AOT)to calculate the proportion of sperm with single-strand DNA breaks(SSBs).Our data showed that sperm concentration and motility in infertile males significantly decreased with the severity of abnormal sperm morphology(both P<0.01).P1 level,P1/P2 ratio,and SSB rate increased with the severity of sperm dysmorphology,whilst the P2 level decreased(all P<O.01).NVs,CDs,and ERC were more common in males with sperm dysmorphology and positively correlated with the SSB rate(all P<O.01).The relationships between the SSB rate and the P1/P2 ratio were also significant(P<0.01).Aberrant protamination may cause sperm dysmorphology and compromise male fertility by impairing sperm's nucleus and cytoplasm maturation,with the P1/P2 ratio potentially serving as a valuable indicator of sperm quality and male fertility.
基金supported by the National Natural Science Foundation of China(Project No.51767018)Natural Science Foundation of Gansu Province(Project No.23JRRA836).
文摘Current methodologies for cleaning wind power anomaly data exhibit limited capabilities in identifying abnormal data within extensive datasets and struggle to accommodate the considerable variability and intricacy of wind farm data.Consequently,a method for cleaning wind power anomaly data by combining image processing with community detection algorithms(CWPAD-IPCDA)is proposed.To precisely identify and initially clean anomalous data,wind power curve(WPC)images are converted into graph structures,which employ the Louvain community recognition algorithm and graph-theoretic methods for community detection and segmentation.Furthermore,the mathematical morphology operation(MMO)determines the main part of the initially cleaned wind power curve images and maps them back to the normal wind power points to complete the final cleaning.The CWPAD-IPCDA method was applied to clean datasets from 25 wind turbines(WTs)in two wind farms in northwest China to validate its feasibility.A comparison was conducted using density-based spatial clustering of applications with noise(DBSCAN)algorithm,an improved isolation forest algorithm,and an image-based(IB)algorithm.The experimental results demonstrate that the CWPAD-IPCDA method surpasses the other three algorithms,achieving an approximately 7.23%higher average data cleaning rate.The mean value of the sum of the squared errors(SSE)of the dataset after cleaning is approximately 6.887 lower than that of the other algorithms.Moreover,the mean of overall accuracy,as measured by the F1-score,exceeds that of the other methods by approximately 10.49%;this indicates that the CWPAD-IPCDA method is more conducive to improving the accuracy and reliability of wind power curve modeling and wind farm power forecasting.
