Escherichia coli has seldom been reported to cause pseudobacteremia. The investigation of an outbreak of amoxycillin clavulanic acid resistant E. coli pseudobacteremia is described. Seventeen cases occurred ove...Escherichia coli has seldom been reported to cause pseudobacteremia. The investigation of an outbreak of amoxycillin clavulanic acid resistant E. coli pseudobacteremia is described. Seventeen cases occurred over a five day period. The source of the E. coli was traced to the blood culture specimen of a patient (index patient) with genuine bacteremia as a result of urinary tract infection. The other 16 case patients had pseudobacteremia which was found to be the result of cross contamination during subculture of blood specimens. The E. coli strain was carried over from the culture bottle of the index patient, through the contaminated gloved hands of a technician to the culture bottles of the other 16 cases. Although the pseudobacteremia occurred over a five day period, they all resulted from cross contamination during blood culture processing within one day. An early outbreak investigation was prompted by the unusual finding of amoxycillin clavulanic acid resistance in the case E. coli isolates in a short period. The relatedness of the E. coli strains from the 17 cases was confirmed by arbitrary primed polymerase chain reaction. Clinicians should be alerted to the possibility of a blood E. coli isolate being a contaminant despite its predominant role as a true pathogen.展开更多
The 3 310-m-high Chia-min Lake records the climatic history since 4 ka B. P. in Taiwan. The warm/wet period before 2.2 ka B.P. seemed to correspond to the later part of the Holocene Megathermal, and the cold/dry perio...The 3 310-m-high Chia-min Lake records the climatic history since 4 ka B. P. in Taiwan. The warm/wet period before 2.2 ka B.P. seemed to correspond to the later part of the Holocene Megathermal, and the cold/dry period during 0-2/2 ka B. P. corresponded to the Katathermal. Before the termination of the Megathermal, an especially warm and humid segment (2, 2-2. 4 ka B. P. ) emerged. The paleoclimatic records from Yuen-yang and Chi-tsai Lakes support the notion that the Megathermal in Taiwan terminated during 2-2. 3 ka B. P. A warm segment (820-1 320 AD) in the Katathermal could be considered the Medieval Warm Period. The climate turned cold and dry after 1 320 AD and this indicated the onset of the Little Ice Age. These paleoclimatic variations are also in good agreement with those recorded in Great Ghost Lake.展开更多
文摘Escherichia coli has seldom been reported to cause pseudobacteremia. The investigation of an outbreak of amoxycillin clavulanic acid resistant E. coli pseudobacteremia is described. Seventeen cases occurred over a five day period. The source of the E. coli was traced to the blood culture specimen of a patient (index patient) with genuine bacteremia as a result of urinary tract infection. The other 16 case patients had pseudobacteremia which was found to be the result of cross contamination during subculture of blood specimens. The E. coli strain was carried over from the culture bottle of the index patient, through the contaminated gloved hands of a technician to the culture bottles of the other 16 cases. Although the pseudobacteremia occurred over a five day period, they all resulted from cross contamination during blood culture processing within one day. An early outbreak investigation was prompted by the unusual finding of amoxycillin clavulanic acid resistance in the case E. coli isolates in a short period. The relatedness of the E. coli strains from the 17 cases was confirmed by arbitrary primed polymerase chain reaction. Clinicians should be alerted to the possibility of a blood E. coli isolate being a contaminant despite its predominant role as a true pathogen.
文摘The 3 310-m-high Chia-min Lake records the climatic history since 4 ka B. P. in Taiwan. The warm/wet period before 2.2 ka B.P. seemed to correspond to the later part of the Holocene Megathermal, and the cold/dry period during 0-2/2 ka B. P. corresponded to the Katathermal. Before the termination of the Megathermal, an especially warm and humid segment (2, 2-2. 4 ka B. P. ) emerged. The paleoclimatic records from Yuen-yang and Chi-tsai Lakes support the notion that the Megathermal in Taiwan terminated during 2-2. 3 ka B. P. A warm segment (820-1 320 AD) in the Katathermal could be considered the Medieval Warm Period. The climate turned cold and dry after 1 320 AD and this indicated the onset of the Little Ice Age. These paleoclimatic variations are also in good agreement with those recorded in Great Ghost Lake.
文摘目的:优化薏苡仁水溶性蛋白提取工艺。方法:用半胱氨酸盐酸盐溶液在碱性条件下提取薏苡仁蛋白,对影响蛋白提取的因素进行单因素考察。结合单因素考察结果,选取浸提温度、浸提p H、料液比、浸提时间设计4因素3水平的正交试验,分析各因素对结果的影响及因素间交互作用。结果:薏苡仁水溶性蛋白最佳提取工艺为:浸提温度40℃,浸提p H 10,料液比1∶20,浸提时间4 h。温度与料液比、温度与时间的交互作用会降低蛋白浸提率。结论:优化后的提取工艺经济简单,稳定可行。