背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能。目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述。方法:由第一作者应用计算机检索Pub...背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能。目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述。方法:由第一作者应用计算机检索PubMed数据库1992年1月至2012年10月及中国期刊网全文数据库1994年1月至2012年12月有关四肢恶性骨肿瘤保肢治疗的文章,英文检索词为"malignant bone tumor,salvage treatment,allograft bone graft,prosthesis and microwave",中文检索词为"恶性骨肿瘤,保肢治疗,大段异体骨,肿瘤假体,微波灭活治疗"。排除重复性研究及Meta分析,共保留31篇文献进行综述。结果与结论:①对于四肢特别是关节周围的恶性骨肿瘤,大多采用人工关节置换、大段同种异体骨移植以及微波灭活治疗。②大段同种异体骨移植后并发症发生率较高,微波灭活治疗技术有新的进展,进一步的研究仍在进行当中。③瘤段骨灭活再植以及乙醇灭活治疗多适用于基层医院。展开更多
Background: Recording jaw movement rhythms in patients with jaw defects is challenging using conventional tracking devices. However, masticatory rhythm is crucial for masticatory performance and nutritional intake. Th...Background: Recording jaw movement rhythms in patients with jaw defects is challenging using conventional tracking devices. However, masticatory rhythm is crucial for masticatory performance and nutritional intake. This study aimed to explore the impact of using a maxillofacial prosthesis to restore masticatory rhythm in mandibulectomy patients with a novel wearable device. Methods: Twelve patients who underwent mandibulectomy and were rehabilitated with maxillofacial prosthesis were recruited. Chewing rate, cycle durations, coefficient of variation of cycle durations (CV), changing times of skin morphology on the back of the ear pinna area (SM), and masticatory performance were measured during gum chewing without and with a denture using a wearable jaw movement rhythm tracking device. A paired t-test and the Pearson correlation coefficient were used for statistical analysis. Results: The chewing rate increased by 8.6 cycles/min with dentures (P P = 0.01). The CV and SM decreased with dentures (P = 0.004 and P = 0.01, respectively). Significant correlations were found between the CV and SM without dentures (P = 0.004). Conclusion: 1. Wearing maxillofacial prostheses can improve masticatory rhythm in patients who undergo mandibulectomy with Eichner B2 occlusal supports. 2. The wearable device is available for measuring masticatory rhythm in patients with jaw defects in clinics. 3. Changing times of the skin morphology on the back of the ear pinna indicate jaw movement stability through a simpler process than the coefficient of variation of cycle durations.展开更多
文摘背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能。目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述。方法:由第一作者应用计算机检索PubMed数据库1992年1月至2012年10月及中国期刊网全文数据库1994年1月至2012年12月有关四肢恶性骨肿瘤保肢治疗的文章,英文检索词为"malignant bone tumor,salvage treatment,allograft bone graft,prosthesis and microwave",中文检索词为"恶性骨肿瘤,保肢治疗,大段异体骨,肿瘤假体,微波灭活治疗"。排除重复性研究及Meta分析,共保留31篇文献进行综述。结果与结论:①对于四肢特别是关节周围的恶性骨肿瘤,大多采用人工关节置换、大段同种异体骨移植以及微波灭活治疗。②大段同种异体骨移植后并发症发生率较高,微波灭活治疗技术有新的进展,进一步的研究仍在进行当中。③瘤段骨灭活再植以及乙醇灭活治疗多适用于基层医院。
文摘Background: Recording jaw movement rhythms in patients with jaw defects is challenging using conventional tracking devices. However, masticatory rhythm is crucial for masticatory performance and nutritional intake. This study aimed to explore the impact of using a maxillofacial prosthesis to restore masticatory rhythm in mandibulectomy patients with a novel wearable device. Methods: Twelve patients who underwent mandibulectomy and were rehabilitated with maxillofacial prosthesis were recruited. Chewing rate, cycle durations, coefficient of variation of cycle durations (CV), changing times of skin morphology on the back of the ear pinna area (SM), and masticatory performance were measured during gum chewing without and with a denture using a wearable jaw movement rhythm tracking device. A paired t-test and the Pearson correlation coefficient were used for statistical analysis. Results: The chewing rate increased by 8.6 cycles/min with dentures (P P = 0.01). The CV and SM decreased with dentures (P = 0.004 and P = 0.01, respectively). Significant correlations were found between the CV and SM without dentures (P = 0.004). Conclusion: 1. Wearing maxillofacial prostheses can improve masticatory rhythm in patients who undergo mandibulectomy with Eichner B2 occlusal supports. 2. The wearable device is available for measuring masticatory rhythm in patients with jaw defects in clinics. 3. Changing times of the skin morphology on the back of the ear pinna indicate jaw movement stability through a simpler process than the coefficient of variation of cycle durations.