目的观察总结应用胺碘酮治疗冠心病合并快速型心律失常的临床效果。方法收集2012年2月—2013年9月在我院急诊科就诊的冠心病快速型心律失常患者113例,观察和总结胺碘酮的临床效果以及应用胺碘酮治疗各种类型快速心律失常的有效性。结果...目的观察总结应用胺碘酮治疗冠心病合并快速型心律失常的临床效果。方法收集2012年2月—2013年9月在我院急诊科就诊的冠心病快速型心律失常患者113例,观察和总结胺碘酮的临床效果以及应用胺碘酮治疗各种类型快速心律失常的有效性。结果经过临床病例的观察和总结,113例冠心病快速型心律失常患者经胺碘酮治疗后,97例显效或有效,总有效率为85.8%;在各心律失常类型中,阵发性房颤的转复率最高,为95.5%,其次为室性早搏,为91.1%,明显高于阵发性室上性心动过速(PSTV)、室性心动过速及持续性房颤的转复率,差异具有统计学意义(χ2=10.4682,P<0.05)。结果显示无效9例,出现不良反应7例,其中有5例患者出现血压下降,降至90/60 mm Hg,2例心率降低至50次/min,经过对症治疗后症状均缓解。结论本研究提示,胺碘酮治疗心律失常类型中,对阵发性房颤的有效率最高,室性早搏其次,两者有效率明显高于对PSTV、室性心动过速及持续性房颤的转复率。临床上治疗冠心病快速心律失常急诊应用胺碘酮起效快,安全性高,值得临床推广使用。展开更多
Most cases of sudden cardiac death are attributed to sustained ventricular tachyarrhythmias(VTs), triggered by acute coronary occlusion. Autonomic dysfunction, an important arrhythmogenic mechanism in this setting, is...Most cases of sudden cardiac death are attributed to sustained ventricular tachyarrhythmias(VTs), triggered by acute coronary occlusion. Autonomic dysfunction, an important arrhythmogenic mechanism in this setting, is being actively investigated, aiming at the advent of preventive strategies. Recent experimental studies have shown vagal withdrawal after anterior myocardial infarction, coinciding with high incidence of VTs, followed by more gradual sympathetic activation coinciding with a second arrhythmia peak. This article summarizes recent knowledge on this intriguing topic, generating hypotheses that can be investigated in future experimental and clinical studies.展开更多
Transcutaneous renal artery denervation （RND） has beeninitially developed for destruction of efferent nerve fireswith luminal delivery of radiofrequency or ultrasonic energyaiming blood pressure reduction in patient...Transcutaneous renal artery denervation （RND） has beeninitially developed for destruction of efferent nerve fireswith luminal delivery of radiofrequency or ultrasonic energyaiming blood pressure reduction in patients with refractoryhypertension. However, other positive results of RNDwere described afterwards, and they include suppression ofatrial fibrillation and ventricular tachycardia （VT） storm.展开更多
文摘目的观察总结应用胺碘酮治疗冠心病合并快速型心律失常的临床效果。方法收集2012年2月—2013年9月在我院急诊科就诊的冠心病快速型心律失常患者113例,观察和总结胺碘酮的临床效果以及应用胺碘酮治疗各种类型快速心律失常的有效性。结果经过临床病例的观察和总结,113例冠心病快速型心律失常患者经胺碘酮治疗后,97例显效或有效,总有效率为85.8%;在各心律失常类型中,阵发性房颤的转复率最高,为95.5%,其次为室性早搏,为91.1%,明显高于阵发性室上性心动过速(PSTV)、室性心动过速及持续性房颤的转复率,差异具有统计学意义(χ2=10.4682,P<0.05)。结果显示无效9例,出现不良反应7例,其中有5例患者出现血压下降,降至90/60 mm Hg,2例心率降低至50次/min,经过对症治疗后症状均缓解。结论本研究提示,胺碘酮治疗心律失常类型中,对阵发性房颤的有效率最高,室性早搏其次,两者有效率明显高于对PSTV、室性心动过速及持续性房颤的转复率。临床上治疗冠心病快速心律失常急诊应用胺碘酮起效快,安全性高,值得临床推广使用。
文摘Most cases of sudden cardiac death are attributed to sustained ventricular tachyarrhythmias(VTs), triggered by acute coronary occlusion. Autonomic dysfunction, an important arrhythmogenic mechanism in this setting, is being actively investigated, aiming at the advent of preventive strategies. Recent experimental studies have shown vagal withdrawal after anterior myocardial infarction, coinciding with high incidence of VTs, followed by more gradual sympathetic activation coinciding with a second arrhythmia peak. This article summarizes recent knowledge on this intriguing topic, generating hypotheses that can be investigated in future experimental and clinical studies.
文摘Transcutaneous renal artery denervation （RND） has beeninitially developed for destruction of efferent nerve fireswith luminal delivery of radiofrequency or ultrasonic energyaiming blood pressure reduction in patients with refractoryhypertension. However, other positive results of RNDwere described afterwards, and they include suppression ofatrial fibrillation and ventricular tachycardia （VT） storm.
