Introduction: A study on the current status of parasitic intestinal helminthes and the efficacy of anthelmintic drug was carried out among primary school pupils at Community Primary School Ogurugu, Uzo-Uwani Local Gov...Introduction: A study on the current status of parasitic intestinal helminthes and the efficacy of anthelmintic drug was carried out among primary school pupils at Community Primary School Ogurugu, Uzo-Uwani Local Government Area, Enugu State. Objectives: The research was conducted in order to determine the prevalence of human intestinal helminthes among primary school pupils, and also to determine the prevalence in relation to age and sex, and to check the efficacy of anthelmintic drug (Levamisole) on the worms, in Ogurugu Uzo-Uwani Local Government Area, Enugu State, Nigeria. Methods: A total of 242 faecal samples were collected randomly from the school children and analyzed using standard parasitological procedures. Results: Data obtained showed an overall prevalence of 143 (59.1%) out of 242 samples and that the efficacy of anthelmintic drug Ergamisole? (Levamisole R12564;Unicure Pvt.ltd India) 50 mg in reducing the worm burden was 99 (82.5%) in 120 samples treated. Age related prevalence and efficacy of anthelmintic varied across the sample groups. There was no significant difference in sex related infections in the sample group (P > 0.5). The efficacy of the drug reduces with the increase in age. Also the efficacy of Levamisole drug in reducing the worm burden were hookworm 59 (89.5%), Ascaris 24 (85.7%), Trichuris 26 (78.6%) while Taenia and Strongyloides showed drug resistance. This indicates that a single dose of the medication is not enough for total elimination of these endo parasites. Conclusion: The study revealed that poor hygienic practices as well as unsanitary conditions were responsible for high prevalence recorded in the area, and advocated health education through primary health care and mass deworming of primary school children as control measures.展开更多
Durch die systematische Untersuchung und grundliche Studie uber eine Leiche von der Zeit der Streitenden Reiche aus dem Grab Nr. 1 am GuoJia-Gang in der Stadt Jingmen der Provinz Hubei wurde festgestellt , daβdiese L...Durch die systematische Untersuchung und grundliche Studie uber eine Leiche von der Zeit der Streitenden Reiche aus dem Grab Nr. 1 am GuoJia-Gang in der Stadt Jingmen der Provinz Hubei wurde festgestellt , daβdiese Leiche vor mehr als 2300 Jahren, namlich in dem mittleren Zeitabschnitt der Streitenden Reiche Chinas , in einem Holzsarg beerdigt wurde und die alteste unter allen bisher in China gefundenen alten Sargleichen ist. Sie gehort grundsatzlich auch zu dem Typ der jeweils 1972 in Changsha und 1975 in Jiangling gefundenen alten Leichen der Westlichen Han-Dynastie. Die kollagenen Bindegewebsfasern aus allen Korperteilen dieser Leiche zeigten eine sehr gut erhaltene Ultrastruktur mit ganz deutlichen, ordentlichen, periodischen Querstreifungen. Zwischen den Kollagenfibrillen war interessanterweise wie bei den beiden Leichen der Westlichen HanDynastie auch eine Menge von Bakteriensporen vorhanden. Auβerdem wurde noch eine groβe Menge von Clonorchis sinensis-und Trichuris trichiura-Eier in dem Darminhalt der alten Leiche gefunden. Uber den Erhaltungszustand und die Faktoren der guten Erhaltung der Leiche wurde diskutiert. Unserer Ansicht nach sei die Erhaltung der Leiche ein Resultat aus einem kombiniertem Effekt von internen und externen Faktoren der Leiche.展开更多
In this report, we present computed tomographic findings of colonic trichuriasis. The patient was a 75-year-old man who complained of abdominal pain, and weight loss. Diagnosis was achieved by colonoscopic biopsy. Abd...In this report, we present computed tomographic findings of colonic trichuriasis. The patient was a 75-year-old man who complained of abdominal pain, and weight loss. Diagnosis was achieved by colonoscopic biopsy. Abdominal computed tomography showed irregular and nodular thickening of the wall of the cecum and ascending colon. Although these findings are nonspecific, they may be one of the findings of trichuriasis. These findings, confirmed by pathologic analysis of the biopsied tissue and KatoKatz parasitological stool flotation technique, revealed adult Trichuris. To our knowledge, this is the first report of colonic trichuriasis indicated by computed tomography.展开更多
文摘Introduction: A study on the current status of parasitic intestinal helminthes and the efficacy of anthelmintic drug was carried out among primary school pupils at Community Primary School Ogurugu, Uzo-Uwani Local Government Area, Enugu State. Objectives: The research was conducted in order to determine the prevalence of human intestinal helminthes among primary school pupils, and also to determine the prevalence in relation to age and sex, and to check the efficacy of anthelmintic drug (Levamisole) on the worms, in Ogurugu Uzo-Uwani Local Government Area, Enugu State, Nigeria. Methods: A total of 242 faecal samples were collected randomly from the school children and analyzed using standard parasitological procedures. Results: Data obtained showed an overall prevalence of 143 (59.1%) out of 242 samples and that the efficacy of anthelmintic drug Ergamisole? (Levamisole R12564;Unicure Pvt.ltd India) 50 mg in reducing the worm burden was 99 (82.5%) in 120 samples treated. Age related prevalence and efficacy of anthelmintic varied across the sample groups. There was no significant difference in sex related infections in the sample group (P > 0.5). The efficacy of the drug reduces with the increase in age. Also the efficacy of Levamisole drug in reducing the worm burden were hookworm 59 (89.5%), Ascaris 24 (85.7%), Trichuris 26 (78.6%) while Taenia and Strongyloides showed drug resistance. This indicates that a single dose of the medication is not enough for total elimination of these endo parasites. Conclusion: The study revealed that poor hygienic practices as well as unsanitary conditions were responsible for high prevalence recorded in the area, and advocated health education through primary health care and mass deworming of primary school children as control measures.
文摘Durch die systematische Untersuchung und grundliche Studie uber eine Leiche von der Zeit der Streitenden Reiche aus dem Grab Nr. 1 am GuoJia-Gang in der Stadt Jingmen der Provinz Hubei wurde festgestellt , daβdiese Leiche vor mehr als 2300 Jahren, namlich in dem mittleren Zeitabschnitt der Streitenden Reiche Chinas , in einem Holzsarg beerdigt wurde und die alteste unter allen bisher in China gefundenen alten Sargleichen ist. Sie gehort grundsatzlich auch zu dem Typ der jeweils 1972 in Changsha und 1975 in Jiangling gefundenen alten Leichen der Westlichen Han-Dynastie. Die kollagenen Bindegewebsfasern aus allen Korperteilen dieser Leiche zeigten eine sehr gut erhaltene Ultrastruktur mit ganz deutlichen, ordentlichen, periodischen Querstreifungen. Zwischen den Kollagenfibrillen war interessanterweise wie bei den beiden Leichen der Westlichen HanDynastie auch eine Menge von Bakteriensporen vorhanden. Auβerdem wurde noch eine groβe Menge von Clonorchis sinensis-und Trichuris trichiura-Eier in dem Darminhalt der alten Leiche gefunden. Uber den Erhaltungszustand und die Faktoren der guten Erhaltung der Leiche wurde diskutiert. Unserer Ansicht nach sei die Erhaltung der Leiche ein Resultat aus einem kombiniertem Effekt von internen und externen Faktoren der Leiche.
文摘In this report, we present computed tomographic findings of colonic trichuriasis. The patient was a 75-year-old man who complained of abdominal pain, and weight loss. Diagnosis was achieved by colonoscopic biopsy. Abdominal computed tomography showed irregular and nodular thickening of the wall of the cecum and ascending colon. Although these findings are nonspecific, they may be one of the findings of trichuriasis. These findings, confirmed by pathologic analysis of the biopsied tissue and KatoKatz parasitological stool flotation technique, revealed adult Trichuris. To our knowledge, this is the first report of colonic trichuriasis indicated by computed tomography.
