Intensity modulated radiation therapy （IMRT） requires the determination of the appropriate multileaf collimator settings to deliver an intensity map. The purpose of this work was to attempt to regulate the shape bet...Intensity modulated radiation therapy （IMRT） requires the determination of the appropriate multileaf collimator settings to deliver an intensity map. The purpose of this work was to attempt to regulate the shape between adjacent multileaf collimator apertures by a leaf sequencing algorithm. To qualify and validate this algorithm, the integral test for the segment of the multileaf collimator of ARTS was performed with clinical intensity map experiments. By comparisons and analyses of the total number of monitor units and number of segments with benchmark results, the proposed algorithm performed well while the segment shape constraint produced segments with more compact shapes when delivering the planned intensity maps, which may help to reduce the multileaf collimator＇s specific effects.展开更多
基金supported by National Natural Science Foundation of China (No. 10805012)Fundamental Research Funds for the Central Universities (Nos. 2010HGXJ0216, 2012HGXJ0057, 2012HGXJ0062, 2012HGXJ0071, 2012HGBZ0190)Seed Foundation of Hefei University of Technology (2012HGZY0007)
文摘Intensity modulated radiation therapy （IMRT） requires the determination of the appropriate multileaf collimator settings to deliver an intensity map. The purpose of this work was to attempt to regulate the shape between adjacent multileaf collimator apertures by a leaf sequencing algorithm. To qualify and validate this algorithm, the integral test for the segment of the multileaf collimator of ARTS was performed with clinical intensity map experiments. By comparisons and analyses of the total number of monitor units and number of segments with benchmark results, the proposed algorithm performed well while the segment shape constraint produced segments with more compact shapes when delivering the planned intensity maps, which may help to reduce the multileaf collimator＇s specific effects.
