目的分析免疫抑制药的药物基因组学研究领域现况。方法检索Web of Science数据库中2012年1月—2022年5月涉及免疫抑制药基因组学研究的相关文献,采用文献计量学方法,利用CiteSpace可视化软件对检索结果进行分析。结果检索筛选后得到106...目的分析免疫抑制药的药物基因组学研究领域现况。方法检索Web of Science数据库中2012年1月—2022年5月涉及免疫抑制药基因组学研究的相关文献,采用文献计量学方法,利用CiteSpace可视化软件对检索结果进行分析。结果检索筛选后得到1062篇相关文献。年发文量呈递增趋势,年累积发文量稳步增长。美国发文最多占发文总量的27.8%,中国紧随其后占15.6%,但两国间未形成较为紧密的合作网络,且中国与其他国家的研究合作关系不够紧密,较为独立。美国哈佛医学院是本领域的主要研究机构,学术合作圈均集中在各自地理区位相近的区域内,跨区域合作较为薄弱,尚未形成广泛的合作关系和学术共同体。发文量前10的作者大致分为两个研究团体,分别以Van Gelder Teun、Hesselink Dennis等和Israni Ajay等为核心作者。研究多集中在他克莫司等钙调磷酸酶抑制药基因组学差异对个体代谢的影响,所研究的免疫抑制药多在移植、炎症性肠病、肾小球肾炎等领域发挥作用。结论免疫抑制药基因组学研究仍然处于上升趋势,美国在该研究领域占据优势;中国次之,位列研究前沿,研究相对独立。实体器官移植领域药物基因组学对钙调磷酸酶抑制药的药动学和药效学影响依然是相对主流的研究方向。展开更多
BACKGROUND： The monosialoganglioside （GM1） is a popular topic of research but the bibliometric analysis of GM1 over the decades in Science Citation Index-Expanded （SCI-E） remains poorly understood. OBJECTIVE： To...BACKGROUND： The monosialoganglioside （GM1） is a popular topic of research but the bibliometric analysis of GM1 over the decades in Science Citation Index-Expanded （SCI-E） remains poorly understood. OBJECTIVE： To identify the global research and to improve the understanding of research trends in the GM1 field from 1942 to 2011. DESIGN： A bibliometric study. DATA RETRIEVAL： We performed a bibliometric analysis based on the SCI-E published by the Institute of Scientific Information. INCLUSIVE CRITERIA： Articles closely related to GM1 were included. Exclusive criteria： （1） Articles related to gangliosidosis, disialo-ganglioside, trisialo-ganglioside or ganglioside GQIb. （2） Document types such as meeting abstracts, reviews, proceedings papers, notes, and letters. MAIN OUTCOME MEASURES： （1） Type of publication output; （2） number of author outputs; （3） distribution of output in subject categories; （4） publication distribution of countries; （5） distribution of output in journals, and （6） distribution of citations in each decade. RESULTS： During 1942 to 2011, there were 10 126 papers on GM1 that were added to the SCI. Articles （8 004） were the most frequently used document type comprising 79.0%, followed by meeting abstracts, reviews and proceedings papers. Research on GM1 could be found in the SCI from 1942, it was developed in the 1970s, greatly increased in the 1980s, and reached a peak in the 1990s, and it was slightly decreased in 2000. The distribution of subject categories showed that GM1 research covered both clinical and basic science research. The USA, Japan, and Germany were the three most productive countries, and the publication numbers in the USA were highest in all decades. The Joumal of Biological Chemistry, Journal of Neurochemistry and Biochemistry were core subject journals in GM1 studies in each decade. CONCLUSION： This study highlights the topics in GM1 research that are being published around the world.展开更多
Purpose: The purpose of this study is to introduce a new concept and term into the scientometric discourse and research—scientometric implosion—and test the idea on the example of the Armenian journals. The article ...Purpose: The purpose of this study is to introduce a new concept and term into the scientometric discourse and research—scientometric implosion—and test the idea on the example of the Armenian journals. The article argues that the existence of a compressed scientific area in the country makes pressure on the journals and after some time this pressure makes one or several journals explode—break the limited national scientific area and move to the international arena. As soon as one of the local journals breaks through this compressed space and appears at an international level, further explosion happens, which makes the other journals follow the same path.Design/methodology/approach: Our research is based on three international scientific databases—WoS, Scopus, and RISC CC, from where we have retrieved information about the Armenian journals indexed there and citations received by those journals and one national database—the Armenian Science Citation Index. Armenian Journal Impact Factor(ArmJIF) was calculated for the local Armenian journals based on the general impact factor formula. Journals were classified according to Gl?nzel and Schubert(2003). Findings: Our results show that the science policy developed by the scientific authorities of Armenia and the introduction of ArmJIF have made the Armenian journals comply with international standards and resulted in some local journals to break the national scientific territory and be indexed in international scientific databases of RISC, Scopus, and WoS. Apart from complying with technical requirements, the journals start publishing articles also in foreign languages. Although nearly half of the local journals are in the fields of social sciences and humanities, only one journal from that field is indexed in international scientific databases. Research limitation: One of the limitations of the study is that it was performed on the example of only one state and the second one is that more time passage is needed to firmly evaluate the results. However, the in展开更多
文章利用Web of Science平台上的美国科学引文索引数据库,用文献计量学的方法统计2008—2017年作者单位署名为昆明理工大学被SCI-EXPANDED收录论文的情况。通过分析被收录论文的数量、文献类型、语种、研究方向、学院分布、作者、来源...文章利用Web of Science平台上的美国科学引文索引数据库,用文献计量学的方法统计2008—2017年作者单位署名为昆明理工大学被SCI-EXPANDED收录论文的情况。通过分析被收录论文的数量、文献类型、语种、研究方向、学院分布、作者、来源刊物、期刊影响因子、被引频次、合作国家/地区等方面,客观反映十年间昆明理工大学的学术水平、科研成果及科学发展状况。展开更多
文摘BACKGROUND： The monosialoganglioside （GM1） is a popular topic of research but the bibliometric analysis of GM1 over the decades in Science Citation Index-Expanded （SCI-E） remains poorly understood. OBJECTIVE： To identify the global research and to improve the understanding of research trends in the GM1 field from 1942 to 2011. DESIGN： A bibliometric study. DATA RETRIEVAL： We performed a bibliometric analysis based on the SCI-E published by the Institute of Scientific Information. INCLUSIVE CRITERIA： Articles closely related to GM1 were included. Exclusive criteria： （1） Articles related to gangliosidosis, disialo-ganglioside, trisialo-ganglioside or ganglioside GQIb. （2） Document types such as meeting abstracts, reviews, proceedings papers, notes, and letters. MAIN OUTCOME MEASURES： （1） Type of publication output; （2） number of author outputs; （3） distribution of output in subject categories; （4） publication distribution of countries; （5） distribution of output in journals, and （6） distribution of citations in each decade. RESULTS： During 1942 to 2011, there were 10 126 papers on GM1 that were added to the SCI. Articles （8 004） were the most frequently used document type comprising 79.0%, followed by meeting abstracts, reviews and proceedings papers. Research on GM1 could be found in the SCI from 1942, it was developed in the 1970s, greatly increased in the 1980s, and reached a peak in the 1990s, and it was slightly decreased in 2000. The distribution of subject categories showed that GM1 research covered both clinical and basic science research. The USA, Japan, and Germany were the three most productive countries, and the publication numbers in the USA were highest in all decades. The Joumal of Biological Chemistry, Journal of Neurochemistry and Biochemistry were core subject journals in GM1 studies in each decade. CONCLUSION： This study highlights the topics in GM1 research that are being published around the world.
文摘Purpose: The purpose of this study is to introduce a new concept and term into the scientometric discourse and research—scientometric implosion—and test the idea on the example of the Armenian journals. The article argues that the existence of a compressed scientific area in the country makes pressure on the journals and after some time this pressure makes one or several journals explode—break the limited national scientific area and move to the international arena. As soon as one of the local journals breaks through this compressed space and appears at an international level, further explosion happens, which makes the other journals follow the same path.Design/methodology/approach: Our research is based on three international scientific databases—WoS, Scopus, and RISC CC, from where we have retrieved information about the Armenian journals indexed there and citations received by those journals and one national database—the Armenian Science Citation Index. Armenian Journal Impact Factor(ArmJIF) was calculated for the local Armenian journals based on the general impact factor formula. Journals were classified according to Gl?nzel and Schubert(2003). Findings: Our results show that the science policy developed by the scientific authorities of Armenia and the introduction of ArmJIF have made the Armenian journals comply with international standards and resulted in some local journals to break the national scientific territory and be indexed in international scientific databases of RISC, Scopus, and WoS. Apart from complying with technical requirements, the journals start publishing articles also in foreign languages. Although nearly half of the local journals are in the fields of social sciences and humanities, only one journal from that field is indexed in international scientific databases. Research limitation: One of the limitations of the study is that it was performed on the example of only one state and the second one is that more time passage is needed to firmly evaluate the results. However, the in
文摘文章利用Web of Science平台上的美国科学引文索引数据库,用文献计量学的方法统计2008—2017年作者单位署名为昆明理工大学被SCI-EXPANDED收录论文的情况。通过分析被收录论文的数量、文献类型、语种、研究方向、学院分布、作者、来源刊物、期刊影响因子、被引频次、合作国家/地区等方面,客观反映十年间昆明理工大学的学术水平、科研成果及科学发展状况。
