A new type of photo-electro-chemical catalytic reactor was designed.Cathode and anode of the new reactor were made of high-purity graphite and titanium dioxide electrode re-spectively.A saturated calomel electrode (SC...A new type of photo-electro-chemical catalytic reactor was designed.Cathode and anode of the new reactor were made of high-purity graphite and titanium dioxide electrode re-spectively.A saturated calomel electrode (SCE) was used as the reference electrode.Under the condition of ultraviolet radiation and anodic bias-voltage,acid scarlet 3R was degraded by the process of photoelectrocatalysis with titanium dioxide electrode in anodic compartment,while it was degraded by electrogenerated Fenton’s reagent and hydrogen peroxide through reducing dissolved oxygen with graphite electrode in catholyte.The new reactor made the best use of photogenerated holes and photogenerated charge on the anode of the new reactor,which achieved the purpose of degrading acid scarlet 3R in the cathodic and anodic compartments simultaneously,i.e.“two electrodes and double effect”.The experimental results showed that,compared with other photoelectrocatalysis reactors (“two electrodes and single effect” reactor),the new reactor has obviously enhanced the degradation of acid scarlet 3R dye.With the con-centration of the dye being 30 mg·L?1 in water,under the operating conditions that when the inert supporting electrolyte concentration was 0.02 mol·L?1 sodium sulfate,initial solution pH = 3,and cathodic potential ?Ec = 0.66 V,the highest decolorizing efficiency of 92% was accomplished in cathodic compartment,and that of 60% in anodic compartment.展开更多
The dopaminergic system controls several vital central nervous system functions, including the control of movement, reward behaviors and cognition. Alterations of dopaminergic signaling are involved in the pathogenesi...The dopaminergic system controls several vital central nervous system functions, including the control of movement, reward behaviors and cognition. Alterations of dopaminergic signaling are involved in the pathogenesis of neurodegenerative and psychiatric disorders, in particular Parkinson’s disease, which are associated with a subtle and chronic inflammatory response. A substantial body of evidence has demonstrated the non-neuronal expression of dopamine, its receptors and of the machinery that governs synthesis, secretion and storage of dopamine across several immune cell types. This review aims to summarize current knowledge on the role and expression of dopamine in immune cells. One of the goals is to decipher the complex mechanisms through which these cell types respond to dopamine, in order to address the impact this has on neurodegenerative and psychiatric pathologies such as Parkinson’s disease. A further aim is to illustrate the gaps in our understanding of the physiological roles of dopamine to encourage more targeted research focused on understanding the consequences of aberrant dopamine production on immune regulation. These highlights may prompt scientists in the field to consider alternative functions of this important neurotransmitter when targeting neuroinflammatory/neurodegenerative pathologies.展开更多
基金the Scientific and Technical Planned Project of Guangdong Province(Grant No.2002C31622) the Natural Science Foundation of Guangdong Province(Grant No.31921).
文摘A new type of photo-electro-chemical catalytic reactor was designed.Cathode and anode of the new reactor were made of high-purity graphite and titanium dioxide electrode re-spectively.A saturated calomel electrode (SCE) was used as the reference electrode.Under the condition of ultraviolet radiation and anodic bias-voltage,acid scarlet 3R was degraded by the process of photoelectrocatalysis with titanium dioxide electrode in anodic compartment,while it was degraded by electrogenerated Fenton’s reagent and hydrogen peroxide through reducing dissolved oxygen with graphite electrode in catholyte.The new reactor made the best use of photogenerated holes and photogenerated charge on the anode of the new reactor,which achieved the purpose of degrading acid scarlet 3R in the cathodic and anodic compartments simultaneously,i.e.“two electrodes and double effect”.The experimental results showed that,compared with other photoelectrocatalysis reactors (“two electrodes and single effect” reactor),the new reactor has obviously enhanced the degradation of acid scarlet 3R dye.With the con-centration of the dye being 30 mg·L?1 in water,under the operating conditions that when the inert supporting electrolyte concentration was 0.02 mol·L?1 sodium sulfate,initial solution pH = 3,and cathodic potential ?Ec = 0.66 V,the highest decolorizing efficiency of 92% was accomplished in cathodic compartment,and that of 60% in anodic compartment.
基金supported by a Research Development Fund(UTS Start-Up Grant 2018)from the University of Technology Sydney to AC。
文摘The dopaminergic system controls several vital central nervous system functions, including the control of movement, reward behaviors and cognition. Alterations of dopaminergic signaling are involved in the pathogenesis of neurodegenerative and psychiatric disorders, in particular Parkinson’s disease, which are associated with a subtle and chronic inflammatory response. A substantial body of evidence has demonstrated the non-neuronal expression of dopamine, its receptors and of the machinery that governs synthesis, secretion and storage of dopamine across several immune cell types. This review aims to summarize current knowledge on the role and expression of dopamine in immune cells. One of the goals is to decipher the complex mechanisms through which these cell types respond to dopamine, in order to address the impact this has on neurodegenerative and psychiatric pathologies such as Parkinson’s disease. A further aim is to illustrate the gaps in our understanding of the physiological roles of dopamine to encourage more targeted research focused on understanding the consequences of aberrant dopamine production on immune regulation. These highlights may prompt scientists in the field to consider alternative functions of this important neurotransmitter when targeting neuroinflammatory/neurodegenerative pathologies.