Acupuncture is regarded as an effective therapy for cerebral ischemia. Different acupuncture ma- nipulations and durations may result in different therapeutic effects. In the present study, the Neig uan （PC6） acupoi...Acupuncture is regarded as an effective therapy for cerebral ischemia. Different acupuncture ma- nipulations and durations may result in different therapeutic effects. In the present study, the Neig uan （PC6） acupoint of rats with occluded middle cerebral arteries was needled at a fixed frequency （3 Hz） with different durations, i.e., 5, 60 and 180 seconds under a twisting-rotating acupuncture method. Results showed that different durations of acupuncture had different therapeutic effects, with 60 seconds yielding a better therapeutic effect than the other two groups. This duration of treatment demonstrated rapid cerebral blood flow, encouraging recovery of neurological function, and small cerebral infarct volume. Experimental findings indicated that under 3 Hz frequency, the treatment of needling Neiguan for 60 seconds is effective for ischemic stroke.展开更多
In this paper,we investigate the performance of the exponential time differencing(ETD)method applied to the rotating shallow water equations.Comparing with explicit time stepping of the same order accuracy in time,the...In this paper,we investigate the performance of the exponential time differencing(ETD)method applied to the rotating shallow water equations.Comparing with explicit time stepping of the same order accuracy in time,the ETD algorithms could reduce the computational time in many cases by allowing the use of large time step sizes while still maintaining numerical stability.To accelerate the ETD simulations,we propose a localized approach that synthesizes the ETD method and overlapping domain decomposition.By dividing the original problem into many subdomain problems of smaller sizes and solving them locally,the proposed approach could speed up the calculation of matrix exponential vector products.Several standard test cases for shallow water equations of one or multiple layers are considered.The results show great potential of the localized ETD method for high-performance computing because each subdomain problem can be naturally solved in parallel at every time step.展开更多
Volume effect has been extensively investigated in several families of solid electrolytes, i.e., expanding the skeleton lattice by bigger-size substitution favors the ionic conduction. However, this effect is not appl...Volume effect has been extensively investigated in several families of solid electrolytes, i.e., expanding the skeleton lattice by bigger-size substitution favors the ionic conduction. However, this effect is not applicable in α-Li2SO4 and α-Na3PO4 based inorganic ionic plastic crystal electrolytes, a unique family of solid electrolytes. Here, it is proposed that the underlying rotational motion effect of polyanion, which is actually inhibited by the substitution of bigger-size polyanion in single-phase solid solution region and causes the unexpected lowering of the ionic conductivity instead, should need the more consideration. Furthermore, through utilizing the rotational motion effect of polyanion, it is given that a new explanation of the ionic conductivities of Li10MP2S12 （M = Si, Ge, Se） electrolytes deviating from the volume effect. These results inspire new vision of rationalization of the high-performance solid electrolytes by tuning the rotational motion effect of polyanion.展开更多
基金supported by a grant from the National Program on Key Basic Research Project(973 Program),No.2010CB530506
文摘Acupuncture is regarded as an effective therapy for cerebral ischemia. Different acupuncture ma- nipulations and durations may result in different therapeutic effects. In the present study, the Neig uan （PC6） acupoint of rats with occluded middle cerebral arteries was needled at a fixed frequency （3 Hz） with different durations, i.e., 5, 60 and 180 seconds under a twisting-rotating acupuncture method. Results showed that different durations of acupuncture had different therapeutic effects, with 60 seconds yielding a better therapeutic effect than the other two groups. This duration of treatment demonstrated rapid cerebral blood flow, encouraging recovery of neurological function, and small cerebral infarct volume. Experimental findings indicated that under 3 Hz frequency, the treatment of needling Neiguan for 60 seconds is effective for ischemic stroke.
基金supported by U.S.Department of Energy through the grants DE-SC0016540,DE-SC0020270U.S.National Science Foundation through the grant DMS-1912626,Office of the Vice President for Research at the University of South Carolina through an ASPIRE grantNatural Science Foundation of China through the grant 11871454.
文摘In this paper,we investigate the performance of the exponential time differencing(ETD)method applied to the rotating shallow water equations.Comparing with explicit time stepping of the same order accuracy in time,the ETD algorithms could reduce the computational time in many cases by allowing the use of large time step sizes while still maintaining numerical stability.To accelerate the ETD simulations,we propose a localized approach that synthesizes the ETD method and overlapping domain decomposition.By dividing the original problem into many subdomain problems of smaller sizes and solving them locally,the proposed approach could speed up the calculation of matrix exponential vector products.Several standard test cases for shallow water equations of one or multiple layers are considered.The results show great potential of the localized ETD method for high-performance computing because each subdomain problem can be naturally solved in parallel at every time step.
基金financially supported by the National Natural Science Foundation of China(Nos.U1430104,51622207 and 51372228)the National Key Research and Development Program of China(No.2017YFB0701600)
文摘Volume effect has been extensively investigated in several families of solid electrolytes, i.e., expanding the skeleton lattice by bigger-size substitution favors the ionic conduction. However, this effect is not applicable in α-Li2SO4 and α-Na3PO4 based inorganic ionic plastic crystal electrolytes, a unique family of solid electrolytes. Here, it is proposed that the underlying rotational motion effect of polyanion, which is actually inhibited by the substitution of bigger-size polyanion in single-phase solid solution region and causes the unexpected lowering of the ionic conductivity instead, should need the more consideration. Furthermore, through utilizing the rotational motion effect of polyanion, it is given that a new explanation of the ionic conductivities of Li10MP2S12 （M = Si, Ge, Se） electrolytes deviating from the volume effect. These results inspire new vision of rationalization of the high-performance solid electrolytes by tuning the rotational motion effect of polyanion.
