Objective:To test the curative effect of human umbilical cord-derived mesenchymal stem cells on rat acute radioactive enteritis and thus in provide clinical therapeutic basis for radiation sickness.Methods:Human umbil...Objective:To test the curative effect of human umbilical cord-derived mesenchymal stem cells on rat acute radioactive enteritis and thus in provide clinical therapeutic basis for radiation sickness.Methods:Human umbilical cord-derived mesenchymal stem cells were cultivated in vitro and the model of acute radioactive enteritis of rats was established.Then,the umbilical cord mesenchymal stem cells were injected into the rats via tail vein.Visual and histopathiological changes of the experimental rats were observed.Results:After the injection,the rats in the prevention group and treatment group had remarkably better survival status than those in the control group.The histological observations revealed that the former also had better intestinal mucosa structure,more regenerative cells and stronger proliferation activity than the latter.Conclusions:Human umbilical cord-derived mesenchymal stem cells have a definite therapeutic effect on acute radioactive enteritis in rats.展开更多
In order to evaluate the impact of the Fukushima nuclear accident on the China Seas, seawater samples from the South China Sea (SCS), the East China Sea (ECS) and the Yellow Sea (YS) were collected in April-June 2011,...In order to evaluate the impact of the Fukushima nuclear accident on the China Seas, seawater samples from the South China Sea (SCS), the East China Sea (ECS) and the Yellow Sea (YS) were collected in April-June 2011, and their 137 Cs activities were measured using low-background -spectrometry. 137Cs activities in the study area ranged from 0.75±0.07 to 1.43±0.08 Bqm 3 with an average of 1.12±0.08 Bq m 3 . 137Cs activities initially increased from the nearshore to the inner shelf, and subsequently decreased from the inner shelf to the outer shelf. Vertical profiles showed higher 137Cs activities at the surface but lower activities at depth in the ECS, suggesting atmospheric input of 137Cs. As such, the distribution pattern of 137Cs in the region was presumably determined by a combination of atmospheric deposition and subsequent mixing between different water masses including the coastal currents, the Yangtze River plume and the Taiwan Warm Currents. Based on the inventory of 93 Bq m2 and the atmospheric deposition flux of 137Cs in the ECS of 32.2 mBq m2 d1 (5.4-42.9 mBq m 2 d1 ) which we estimated, we derived the residence time of 137Cs in the upper water column to be 66d (45-95 d). We concluded that in terms of 137Cs, the ECS was less impacted by the Fukushima accident as compared to the Chernobyl accident. The released amount of 137Cs into the ECS from the Fukushima accident was minute.展开更多
基金supported by Wu Zuze Science and Technology Development Foundation of Beijing
文摘Objective:To test the curative effect of human umbilical cord-derived mesenchymal stem cells on rat acute radioactive enteritis and thus in provide clinical therapeutic basis for radiation sickness.Methods:Human umbilical cord-derived mesenchymal stem cells were cultivated in vitro and the model of acute radioactive enteritis of rats was established.Then,the umbilical cord mesenchymal stem cells were injected into the rats via tail vein.Visual and histopathiological changes of the experimental rats were observed.Results:After the injection,the rats in the prevention group and treatment group had remarkably better survival status than those in the control group.The histological observations revealed that the former also had better intestinal mucosa structure,more regenerative cells and stronger proliferation activity than the latter.Conclusions:Human umbilical cord-derived mesenchymal stem cells have a definite therapeutic effect on acute radioactive enteritis in rats.
基金supported by the National Basic Research Program of China(2009CB421200)
文摘In order to evaluate the impact of the Fukushima nuclear accident on the China Seas, seawater samples from the South China Sea (SCS), the East China Sea (ECS) and the Yellow Sea (YS) were collected in April-June 2011, and their 137 Cs activities were measured using low-background -spectrometry. 137Cs activities in the study area ranged from 0.75±0.07 to 1.43±0.08 Bqm 3 with an average of 1.12±0.08 Bq m 3 . 137Cs activities initially increased from the nearshore to the inner shelf, and subsequently decreased from the inner shelf to the outer shelf. Vertical profiles showed higher 137Cs activities at the surface but lower activities at depth in the ECS, suggesting atmospheric input of 137Cs. As such, the distribution pattern of 137Cs in the region was presumably determined by a combination of atmospheric deposition and subsequent mixing between different water masses including the coastal currents, the Yangtze River plume and the Taiwan Warm Currents. Based on the inventory of 93 Bq m2 and the atmospheric deposition flux of 137Cs in the ECS of 32.2 mBq m2 d1 (5.4-42.9 mBq m 2 d1 ) which we estimated, we derived the residence time of 137Cs in the upper water column to be 66d (45-95 d). We concluded that in terms of 137Cs, the ECS was less impacted by the Fukushima accident as compared to the Chernobyl accident. The released amount of 137Cs into the ECS from the Fukushima accident was minute.
