Recently watershed prioritization has become a pragmatic approach for watershed management and natural resources development. Wadi Shueib is a Jordan Rift valley and covers an area of 177.8 km<sup>2</sup>....Recently watershed prioritization has become a pragmatic approach for watershed management and natural resources development. Wadi Shueib is a Jordan Rift valley and covers an area of 177.8 km<sup>2</sup>. The upper catchment is of dry Mediterranean climate, whereas the lower part is arid. The drainage network is sub-dendritic pattern, with a trellis pattern developed due to the influence of W. Shueib structure. Fourteen mini-watersheds were delineated and designated as (MW 1 to MW 14) for prioritization purposes. Morphometric analysis, and soil erosion susceptibility analysis were conducted, and their values were calculated for each mini-watersheds. Based on value/relationship with erodibility, different prioritization ranks were ascribed following the computation of compound factors. Based on morphometric and soil erosion susceptibility analysis, and the resultant ranks, the mini-watersheds have been classified into four categories in relation to their priority for soil conservation measures: very high, high, moderate, and low. It is found that 64.3% of the 3<sup>rd</sup> order mini-watersheds are classified in the categories of very high and high priority. Based on soil erosion susceptibility analysis, three mini-watersheds are of very high priority and three are of high priority. The integration of morphometric and soil erosion susceptibility methods shows that mini-watersheds no.2 and no.3 are common mini-watersheds, and can be classified in the class of moderate and low priority respectively. By contrast, two mini-watersheds (no.8 and no.13) are categorized in the class of high priority based on morphometric analysis, and are classified in the category of very high priority based on soil erosion susceptibility analysis. Similarly, mini-watershed no.14 can be placed in the category of very high priority based on morphometric analysis, and ranks in the category of high priority based on soil erosion susceptibility analysis. With reference to the integration of the two methods of prioritization, it can be con展开更多
Remote sensing and GIS techniques were employed for prioritization of the Zerqa River watershed. Forty-three 4th order sub-watersheds were prioritized based on morphometric and Principal Component Analysis (PCA), in o...Remote sensing and GIS techniques were employed for prioritization of the Zerqa River watershed. Forty-three 4th order sub-watersheds were prioritized based on morphometric and Principal Component Analysis (PCA), in order to examine the effectiveness of morphometric parameters in watershed prioritization. A comparison has been carried out between the results achieved through applying the two methods of analysis (morphometric and PCA). Afterwards, suitable measures are proposed for soil and water conservation. Topo sheets and ASTER DEM have been employed to demarcate the 43 sub-watersheds, to extract the drainage networks, and to compile the required thematic maps such as slope categories and elevation. LANDSAT 8 image (April-2015) is employed to generate land use/cover maps using ENVI (v 5.1) software. The soil map of the watershed has been digitized using Arc GIS software. Prioritization of the 43 sub-watersheds was performed using ten linear and shape parameters, and three parameters which are highly correlated with components 1 and 2. Subsequently, different sub-watersheds were prioritized by ascribing ranks based on the calculated compound parameters (Cp) using the two approaches. Comparison of the results revealed that prioritization of watersheds based on morphometric analysis is more consistent and serves for better decision making in conservation planning as compared with the PCA approach. The recommended soil conservation measures are prescribed in accordance with the specified priority, in order to avoid undesirable effects on land and environment. Sub-watersheds classified under high priority class are subjected to high erosion risk, thus, creating an urgent need for applying soil and water conservation measures. It is expected that decision makers will pay sufficient attention to the present results/information, activate programs encouraging soil conservation, integrated watershed management, and will continue working on the afforestation of the government-owned sloping lands. Such a viable approach c展开更多
The aim of liver transplantation(LT) for hepatocellular carcinoma(HCC) is to ensure a rate of disease-free survival similar to that of patients transplanted due to benign disease. Therefore, we are forced to adopt str...The aim of liver transplantation(LT) for hepatocellular carcinoma(HCC) is to ensure a rate of disease-free survival similar to that of patients transplanted due to benign disease. Therefore, we are forced to adopt strict criteria when selecting candidates for LT and prioritizing patients on the waiting list(WL), to have clarified indications for bridging therapy for groups at risk for progression or recurrence, and to establish certain limits for downstaging therapies. Although the Milan criteria(MC) remain the standard and most employed criteria for indication of HCC patients for LT by far, in the coming years, criteria will be consolidated that take into account not only data regarding the size/volume and number of tumors but also their biology. This criteria will mainly include the alpha fetoprotein(AFP) values and, in view of their wide variability, any of the published logarithmic models for the selection of candidates for LT. Bridging therapy is necessary for HCC patients on the WL who meet the MC and have the possibility of experiencing a delay for LT greater than 6 mo or any of the known risk factors for recurrence. It is difficult to define single AFP values that would indicate bridging therapy(200, 300 or 400 ng/m L); therefore, it is preferable to rely on the criteria of a French AFP model score > 2. Other single indications for bridging therapy include a tumor diameter greater than 3 cm, more than one tumor, and having an AFP slope greater than 15 ng/m L per month or > 50 ng/m L for three months during strict monitoring while on the WL. When considering the inclusion of patients on the WL who do not meet the MC, it is mandatory to determine their eligibility for downstaging therapy prior to inclusion. The upper limit for this therapy could be one lesion up to 8 cm, 2-3 lesions with a total tumor diameter up to 8 cm, or a total tumor volume of 115 cm^3. Lastly, liver allocation and the prioritization of patients with HCC onthe WL should take into account the recently described HCC model for end-stage l展开更多
The occurrence and impacts of emerging organic contaminants(EOCs)in the aquatic environment have gained widespread attention over the past two decades.Due to large number of potential contaminants,monitoring campaigns...The occurrence and impacts of emerging organic contaminants(EOCs)in the aquatic environment have gained widespread attention over the past two decades.Due to large number of potential contaminants,monitoring campaigns,treatment plants,and proposed regulations should preferentially focus on specific pollutants with the highest potential for ecological and human health effects.In the present study,a multi-criteria screening approach based on hazard and exposure potentials was developed for prioritization of 405 unregulated EOCs already present in Chinese surface water.Hazard potential,exposure potential,and risk quotients for ecological and human health effects were quantitatively analyzed and used to screen contaminants.The hazard potential was defined by contaminant persistence,bioaccumulation,ecotoxicity,and human health effects;similarly,the exposure potential was a function of contaminant concentration and detection frequency.In total,123 compounds passed the preselection process,which involved a priority index equal to the normalized hazard potential multiplied by the normalized exposure potential.Based on the prioritization scheme,11 compounds were identified as top-priority,and 37 chemicals were defined as high-priority.The results obtained by the priority index were compared with four other prioritization schemes based on exposure potential,hazard potential,or risk quotients for ecological effects or human health.The priority index effectively captured and integrated the results from the more simplistic prioritization schemes.Based on identified data gaps,four uncertainty categories were classified to recommend:①regular monitoring,derivation of environmental quality standards,and development of control strategies;②increased monitoring;③fortified hazard assessment;and④increased efforts to collect occurrence and toxicity data.Overall,20 pollutants were recommended as priority EOCs.The prioritized list of contaminants provides the necessary information for authoritative regulations to monitor,control,展开更多
An option prioritization technique is developed to efficiently elicit the preferences, both unknown and crisp, of decision makers （DMs） in strategic conflicts. In the Graph Model for Conflict Resolution, each DM has...An option prioritization technique is developed to efficiently elicit the preferences, both unknown and crisp, of decision makers （DMs） in strategic conflicts. In the Graph Model for Conflict Resolution, each DM has one or more options, each of which may be selected or not. A state, or possible scenario, is formed when all DMs make an option selection. The software GMCR II contains an option prioritization procedure that makes it easy for a modeUer to enter a DM＇s crisp preference ordering over the states using prioritized statements describing the DM＇s preferred option combinations. This procedure is extended by adding two new logical connectives that describe uncertainty of preference. For each DM, a range of possible scores for each feasible state can then be calculated, facilitating the determination of a preference ordering containing uncertainty by comparing and ranking scores. To demonstrate how this new methodology can be used to represent tmknown preferences in a real-world decision problem, it is applied to a Canadian dispute over proposed water exports.展开更多
Antibiotics have received extensive attention due to their sophisticated effects on human health and ecosystems.However,there is an extreme scarcity of information on composition,content,geographic distribution,and ri...Antibiotics have received extensive attention due to their sophisticated effects on human health and ecosystems.However,there is an extreme scarcity of information on composition,content,geographic distribution,and risk of riverine antibiotics at a large spatial scale.Based on a systematic review of over 600 pieces of literature(1999-2021),we established a global dataset containing more than 90,000 records covering 169 antibiotics and their metabolites in surface water and sediment across 76 countries.The occurrence of prioritized antibiotics largely depended on socioeconomic developmental levels,and the current“hotspots”of polluted rivers were found mostly in less developed countries or emerging economies(e.g.,some in Africa,South America,and Asia).By developing the screening protocol for risk-based prioritization of antibiotics,we advanced a rank list of antibiotics for guiding formulation of region-specific strategies,which highlighted the importance of whole life cycle management of antibiotics in health maintenance of the world’s rivers.展开更多
Test Case Prioritization(TCP)techniques perform better than other regression test optimization techniques including Test Suite Reduction(TSR)and Test Case Selection(TCS).Many TCP techniques are available,and their per...Test Case Prioritization(TCP)techniques perform better than other regression test optimization techniques including Test Suite Reduction(TSR)and Test Case Selection(TCS).Many TCP techniques are available,and their performance is usually measured through a metric Average Percentage of Fault Detection(APFD).This metric is value-neutral because it only works well when all test cases have the same cost,and all faults have the same severity.Using APFD for performance evaluation of test case orders where test cases cost or faults severity varies is prone to produce false results.Therefore,using the right metric for performance evaluation of TCP techniques is very important to get reliable and correct results.In this paper,two value-based TCP techniques have been introduced using Genetic Algorithm(GA)including Value-Cognizant Fault Detection-Based TCP(VCFDB-TCP)and Value-Cognizant Requirements Coverage-Based TCP(VCRCB-TCP).Two novel value-based performance evaluation metrics are also introduced for value-based TCP including Average Percentage of Fault Detection per value(APFDv)and Average Percentage of Requirements Coverage per value(APRCv).Two case studies are performed to validate proposed techniques and performance evaluation metrics.The proposed GA-based techniques outperformed the existing state-of-the-art TCP techniques including Original Order(OO),Reverse Order(REV-O),Random Order(RO),and Greedy algorithm.展开更多
文摘Recently watershed prioritization has become a pragmatic approach for watershed management and natural resources development. Wadi Shueib is a Jordan Rift valley and covers an area of 177.8 km<sup>2</sup>. The upper catchment is of dry Mediterranean climate, whereas the lower part is arid. The drainage network is sub-dendritic pattern, with a trellis pattern developed due to the influence of W. Shueib structure. Fourteen mini-watersheds were delineated and designated as (MW 1 to MW 14) for prioritization purposes. Morphometric analysis, and soil erosion susceptibility analysis were conducted, and their values were calculated for each mini-watersheds. Based on value/relationship with erodibility, different prioritization ranks were ascribed following the computation of compound factors. Based on morphometric and soil erosion susceptibility analysis, and the resultant ranks, the mini-watersheds have been classified into four categories in relation to their priority for soil conservation measures: very high, high, moderate, and low. It is found that 64.3% of the 3<sup>rd</sup> order mini-watersheds are classified in the categories of very high and high priority. Based on soil erosion susceptibility analysis, three mini-watersheds are of very high priority and three are of high priority. The integration of morphometric and soil erosion susceptibility methods shows that mini-watersheds no.2 and no.3 are common mini-watersheds, and can be classified in the class of moderate and low priority respectively. By contrast, two mini-watersheds (no.8 and no.13) are categorized in the class of high priority based on morphometric analysis, and are classified in the category of very high priority based on soil erosion susceptibility analysis. Similarly, mini-watershed no.14 can be placed in the category of very high priority based on morphometric analysis, and ranks in the category of high priority based on soil erosion susceptibility analysis. With reference to the integration of the two methods of prioritization, it can be con
文摘Remote sensing and GIS techniques were employed for prioritization of the Zerqa River watershed. Forty-three 4th order sub-watersheds were prioritized based on morphometric and Principal Component Analysis (PCA), in order to examine the effectiveness of morphometric parameters in watershed prioritization. A comparison has been carried out between the results achieved through applying the two methods of analysis (morphometric and PCA). Afterwards, suitable measures are proposed for soil and water conservation. Topo sheets and ASTER DEM have been employed to demarcate the 43 sub-watersheds, to extract the drainage networks, and to compile the required thematic maps such as slope categories and elevation. LANDSAT 8 image (April-2015) is employed to generate land use/cover maps using ENVI (v 5.1) software. The soil map of the watershed has been digitized using Arc GIS software. Prioritization of the 43 sub-watersheds was performed using ten linear and shape parameters, and three parameters which are highly correlated with components 1 and 2. Subsequently, different sub-watersheds were prioritized by ascribing ranks based on the calculated compound parameters (Cp) using the two approaches. Comparison of the results revealed that prioritization of watersheds based on morphometric analysis is more consistent and serves for better decision making in conservation planning as compared with the PCA approach. The recommended soil conservation measures are prescribed in accordance with the specified priority, in order to avoid undesirable effects on land and environment. Sub-watersheds classified under high priority class are subjected to high erosion risk, thus, creating an urgent need for applying soil and water conservation measures. It is expected that decision makers will pay sufficient attention to the present results/information, activate programs encouraging soil conservation, integrated watershed management, and will continue working on the afforestation of the government-owned sloping lands. Such a viable approach c
文摘The aim of liver transplantation(LT) for hepatocellular carcinoma(HCC) is to ensure a rate of disease-free survival similar to that of patients transplanted due to benign disease. Therefore, we are forced to adopt strict criteria when selecting candidates for LT and prioritizing patients on the waiting list(WL), to have clarified indications for bridging therapy for groups at risk for progression or recurrence, and to establish certain limits for downstaging therapies. Although the Milan criteria(MC) remain the standard and most employed criteria for indication of HCC patients for LT by far, in the coming years, criteria will be consolidated that take into account not only data regarding the size/volume and number of tumors but also their biology. This criteria will mainly include the alpha fetoprotein(AFP) values and, in view of their wide variability, any of the published logarithmic models for the selection of candidates for LT. Bridging therapy is necessary for HCC patients on the WL who meet the MC and have the possibility of experiencing a delay for LT greater than 6 mo or any of the known risk factors for recurrence. It is difficult to define single AFP values that would indicate bridging therapy(200, 300 or 400 ng/m L); therefore, it is preferable to rely on the criteria of a French AFP model score > 2. Other single indications for bridging therapy include a tumor diameter greater than 3 cm, more than one tumor, and having an AFP slope greater than 15 ng/m L per month or > 50 ng/m L for three months during strict monitoring while on the WL. When considering the inclusion of patients on the WL who do not meet the MC, it is mandatory to determine their eligibility for downstaging therapy prior to inclusion. The upper limit for this therapy could be one lesion up to 8 cm, 2-3 lesions with a total tumor diameter up to 8 cm, or a total tumor volume of 115 cm^3. Lastly, liver allocation and the prioritization of patients with HCC onthe WL should take into account the recently described HCC model for end-stage l
基金supported by the Major Science and Technology Program for Water Pollution Control and Treatment in China (2017ZX07202)Beijing Science and Technology Planning Project (Z191100006919003)
文摘The occurrence and impacts of emerging organic contaminants(EOCs)in the aquatic environment have gained widespread attention over the past two decades.Due to large number of potential contaminants,monitoring campaigns,treatment plants,and proposed regulations should preferentially focus on specific pollutants with the highest potential for ecological and human health effects.In the present study,a multi-criteria screening approach based on hazard and exposure potentials was developed for prioritization of 405 unregulated EOCs already present in Chinese surface water.Hazard potential,exposure potential,and risk quotients for ecological and human health effects were quantitatively analyzed and used to screen contaminants.The hazard potential was defined by contaminant persistence,bioaccumulation,ecotoxicity,and human health effects;similarly,the exposure potential was a function of contaminant concentration and detection frequency.In total,123 compounds passed the preselection process,which involved a priority index equal to the normalized hazard potential multiplied by the normalized exposure potential.Based on the prioritization scheme,11 compounds were identified as top-priority,and 37 chemicals were defined as high-priority.The results obtained by the priority index were compared with four other prioritization schemes based on exposure potential,hazard potential,or risk quotients for ecological effects or human health.The priority index effectively captured and integrated the results from the more simplistic prioritization schemes.Based on identified data gaps,four uncertainty categories were classified to recommend:①regular monitoring,derivation of environmental quality standards,and development of control strategies;②increased monitoring;③fortified hazard assessment;and④increased efforts to collect occurrence and toxicity data.Overall,20 pollutants were recommended as priority EOCs.The prioritized list of contaminants provides the necessary information for authoritative regulations to monitor,control,
基金Acknowledgments This work was supported by the Scientific Innovation Project of Graduate Students in Jiangsu Province in China （Grant No. CXZZ12-0263）, the National Natural Science Foundation of China （Grant No. 71471087）, as well as by the Natural Sciences and Engineering Research Council of Canada. The authors wish to express their sincere appreciation to the anonymous referees, the Associate Editor, and the editor-in-chief for furnishing comments and constructive suggestions that significantly improved the quality of their article. The authors would also like to thank Mr. Conrad Hipel for editing the paper.
文摘An option prioritization technique is developed to efficiently elicit the preferences, both unknown and crisp, of decision makers （DMs） in strategic conflicts. In the Graph Model for Conflict Resolution, each DM has one or more options, each of which may be selected or not. A state, or possible scenario, is formed when all DMs make an option selection. The software GMCR II contains an option prioritization procedure that makes it easy for a modeUer to enter a DM＇s crisp preference ordering over the states using prioritized statements describing the DM＇s preferred option combinations. This procedure is extended by adding two new logical connectives that describe uncertainty of preference. For each DM, a range of possible scores for each feasible state can then be calculated, facilitating the determination of a preference ordering containing uncertainty by comparing and ranking scores. To demonstrate how this new methodology can be used to represent tmknown preferences in a real-world decision problem, it is applied to a Canadian dispute over proposed water exports.
基金supported by the National Key Basic Research Program of China(2021YFC3200901)National Natural Science Foundation of China(51721006,51925901,and 52100204)CAS Youth Interdisciplinary Team(JCTD-2021-13).
文摘Antibiotics have received extensive attention due to their sophisticated effects on human health and ecosystems.However,there is an extreme scarcity of information on composition,content,geographic distribution,and risk of riverine antibiotics at a large spatial scale.Based on a systematic review of over 600 pieces of literature(1999-2021),we established a global dataset containing more than 90,000 records covering 169 antibiotics and their metabolites in surface water and sediment across 76 countries.The occurrence of prioritized antibiotics largely depended on socioeconomic developmental levels,and the current“hotspots”of polluted rivers were found mostly in less developed countries or emerging economies(e.g.,some in Africa,South America,and Asia).By developing the screening protocol for risk-based prioritization of antibiotics,we advanced a rank list of antibiotics for guiding formulation of region-specific strategies,which highlighted the importance of whole life cycle management of antibiotics in health maintenance of the world’s rivers.
文摘Test Case Prioritization(TCP)techniques perform better than other regression test optimization techniques including Test Suite Reduction(TSR)and Test Case Selection(TCS).Many TCP techniques are available,and their performance is usually measured through a metric Average Percentage of Fault Detection(APFD).This metric is value-neutral because it only works well when all test cases have the same cost,and all faults have the same severity.Using APFD for performance evaluation of test case orders where test cases cost or faults severity varies is prone to produce false results.Therefore,using the right metric for performance evaluation of TCP techniques is very important to get reliable and correct results.In this paper,two value-based TCP techniques have been introduced using Genetic Algorithm(GA)including Value-Cognizant Fault Detection-Based TCP(VCFDB-TCP)and Value-Cognizant Requirements Coverage-Based TCP(VCRCB-TCP).Two novel value-based performance evaluation metrics are also introduced for value-based TCP including Average Percentage of Fault Detection per value(APFDv)and Average Percentage of Requirements Coverage per value(APRCv).Two case studies are performed to validate proposed techniques and performance evaluation metrics.The proposed GA-based techniques outperformed the existing state-of-the-art TCP techniques including Original Order(OO),Reverse Order(REV-O),Random Order(RO),and Greedy algorithm.
