目的 研究孕妇孕妇体质量指数及其孕期增重对妊娠结局的影响.方法 选取2005～2008年在本院分娩符合标准的孕妇1 897例,根据不同的孕妇体质量指数分为3组,根据孕期体重增大的不同幅度分为3组,比较各组的剖宫产率、新生儿窒息率、巨大儿...目的 研究孕妇孕妇体质量指数及其孕期增重对妊娠结局的影响.方法 选取2005～2008年在本院分娩符合标准的孕妇1 897例,根据不同的孕妇体质量指数分为3组,根据孕期体重增大的不同幅度分为3组,比较各组的剖宫产率、新生儿窒息率、巨大儿发生率、产后出血率、早产率、低体重儿发生率.结果 超重组的剖宫产率（36.04% vs 28.03%）、巨大儿发生率（10.41% vs 6.83%）、新生儿窒息率（8.63% vs 2.89%）、早产（5.33% vs 2.09%）、低出生体重（4.82% vs 2.49%）均高于正常体重组（均P＆lt;0.05）,消瘦组早产、低出生体重发生率高于正常体重组（6.59% vs 2.09%,5.43% vs 2.49%,均P＆lt;0.05）.孕期体重增长过多或者增重不足组妊娠结局明显差于增重合适组（P＆lt;0.05）.增重过多组剖宫产、新生儿窒息、早产、低出生体重发生率约为增重合适组的2倍[OR分别为1.82（95%CI 1.47～2.26）,2.34（95%CI 1.43～3.84）,2.20（95%CI 1.25～3.86）1.92（95%CI 1.06～3.47）,均P＆lt;0.05].结论 孕妇体重指数、孕期体重增长的增幅对分娩结局有影响,孕前保持正常体重、孕期合理营养控制适宜的体重增长有利于取得理想的分娩结局.展开更多
目的探讨高危妊娠宫内缺氧胎儿血流动力学指标变化及其对围生儿结局等影响。方法选取2017年12月-2019年10月收治的高危妊娠130例,根据是否存在胎儿宫内缺氧将其分为缺氧组(45例)和无缺氧组(85例)两组。比较两组胎儿彩色多普勒超声检查...目的探讨高危妊娠宫内缺氧胎儿血流动力学指标变化及其对围生儿结局等影响。方法选取2017年12月-2019年10月收治的高危妊娠130例,根据是否存在胎儿宫内缺氧将其分为缺氧组(45例)和无缺氧组(85例)两组。比较两组胎儿彩色多普勒超声检查结果和围生儿结局,新生儿出生后7和28 d新生儿神经行为测定(NBNA)评分,以及新生儿出生后6和12个月智力发育指数(MDI)和运动发育指数(PDI)。结果缺氧组大脑中动脉(MCA)收缩期最大血流速度与舒张末期血流速度比值(S/D)、搏动指数(PI)、阻力指数(RI)和脑-胎盘率(CPR)均低于无缺氧组,而脐动脉(UA)S/D、PI和RI均高于无缺氧组,新生儿出生孕周、出生体质量和出生后1 min Apgar评分短于或低于无缺氧组,剖宫产率和胎儿宫内生长受限、新生儿窒息发生率均高于无缺氧组,新生儿出生后7和28 d NBNA评分及新生儿出生后6和12个月MDI和PDI均低于无缺氧组,差异有统计学意义(P<0.05或P<0.01)。结论高危妊娠宫内缺氧可导致胎儿血流动力学指标改变,彩色多普勒超声检测高危妊娠胎儿MCA和UA血流动力学指标有助于及时发现胎儿宫内缺氧,提高生育质量。展开更多
Objective:To explore the value of increased fetal cardio thoracic ratio(CTR)in predicting adverse fetal pregnancy outcome during 11-13+6 weeks.Methods:The ultrasonographic features,chromosome or gene detection and the...Objective:To explore the value of increased fetal cardio thoracic ratio(CTR)in predicting adverse fetal pregnancy outcome during 11-13+6 weeks.Methods:The ultrasonographic features,chromosome or gene detection and the pregnancy outcome of 86 fetuses with increased CTR at 11-13+6 weeks’gestation were retrospectively analyzed.Fetuses were divided into non-structural malformation group(46 cases)and structural malformation group(40 cases)according to results of fetal ultrasound examination.The differences of CTR and nuchal translucency thickness(NT)between the two groups were compared by t test.The area under the curve(AUC)was calculated by constructing the receiver operating curve(ROC)to determine the best diagnostic threshold,sensitivity and specificity of CTR and NT in predicting chromosomal abnormalities.Results:All the 86 fetuses had serious problems such as chromosome or gene abnormalities,or structural malformations.The CTR and NT of the structural malformation group were significantly higher than those of the non-structural malformation group,and the difference was statistically significant(P<0.05).Through villous biopsy of 60 fetuses,47 cases(78.3%,47/60)with haemoglobin Bart’s disease,10 cases(16.7%,10/60)with chromosomal abnormalities were detected,and none abnormalities were detected in other 3 cases.According to the ROC curve,the AUC for CTR and NT to predict chromosomal abnormalities are 0.691 and 0.954,respectively,and the diagnostic cut-off values are 0.57 and 3.6 mm,respectively.The sensitivity is 60.0%and 100%,the specificity is about 79.6%and 85.7%,respectively.Follow-up showed that 5 cases of fetal were death intrauterine,and the remaining 81 cases were induced to labor.The specificity of CTR increase in predicting adverse pregnancy outcome was 100%.Conclusion:The increase of CTR in 11-13+6 weeks of gestation indicates that the fetus may have serious problems and poor clinical prognosis.Attention should be paid to the accurate evaluation of CTR in early pregnancy so as to provide reference for展开更多
文摘目的 研究孕妇孕妇体质量指数及其孕期增重对妊娠结局的影响.方法 选取2005～2008年在本院分娩符合标准的孕妇1 897例,根据不同的孕妇体质量指数分为3组,根据孕期体重增大的不同幅度分为3组,比较各组的剖宫产率、新生儿窒息率、巨大儿发生率、产后出血率、早产率、低体重儿发生率.结果 超重组的剖宫产率（36.04% vs 28.03%）、巨大儿发生率（10.41% vs 6.83%）、新生儿窒息率（8.63% vs 2.89%）、早产（5.33% vs 2.09%）、低出生体重（4.82% vs 2.49%）均高于正常体重组（均P＆lt;0.05）,消瘦组早产、低出生体重发生率高于正常体重组（6.59% vs 2.09%,5.43% vs 2.49%,均P＆lt;0.05）.孕期体重增长过多或者增重不足组妊娠结局明显差于增重合适组（P＆lt;0.05）.增重过多组剖宫产、新生儿窒息、早产、低出生体重发生率约为增重合适组的2倍[OR分别为1.82（95%CI 1.47～2.26）,2.34（95%CI 1.43～3.84）,2.20（95%CI 1.25～3.86）1.92（95%CI 1.06～3.47）,均P＆lt;0.05].结论 孕妇体重指数、孕期体重增长的增幅对分娩结局有影响,孕前保持正常体重、孕期合理营养控制适宜的体重增长有利于取得理想的分娩结局.
文摘目的探讨高危妊娠宫内缺氧胎儿血流动力学指标变化及其对围生儿结局等影响。方法选取2017年12月-2019年10月收治的高危妊娠130例,根据是否存在胎儿宫内缺氧将其分为缺氧组(45例)和无缺氧组(85例)两组。比较两组胎儿彩色多普勒超声检查结果和围生儿结局,新生儿出生后7和28 d新生儿神经行为测定(NBNA)评分,以及新生儿出生后6和12个月智力发育指数(MDI)和运动发育指数(PDI)。结果缺氧组大脑中动脉(MCA)收缩期最大血流速度与舒张末期血流速度比值(S/D)、搏动指数(PI)、阻力指数(RI)和脑-胎盘率(CPR)均低于无缺氧组,而脐动脉(UA)S/D、PI和RI均高于无缺氧组,新生儿出生孕周、出生体质量和出生后1 min Apgar评分短于或低于无缺氧组,剖宫产率和胎儿宫内生长受限、新生儿窒息发生率均高于无缺氧组,新生儿出生后7和28 d NBNA评分及新生儿出生后6和12个月MDI和PDI均低于无缺氧组,差异有统计学意义(P<0.05或P<0.01)。结论高危妊娠宫内缺氧可导致胎儿血流动力学指标改变,彩色多普勒超声检测高危妊娠胎儿MCA和UA血流动力学指标有助于及时发现胎儿宫内缺氧,提高生育质量。
基金Guangdong Provincial Medical Research Fund(No.A2018159)。
文摘Objective:To explore the value of increased fetal cardio thoracic ratio(CTR)in predicting adverse fetal pregnancy outcome during 11-13+6 weeks.Methods:The ultrasonographic features,chromosome or gene detection and the pregnancy outcome of 86 fetuses with increased CTR at 11-13+6 weeks’gestation were retrospectively analyzed.Fetuses were divided into non-structural malformation group(46 cases)and structural malformation group(40 cases)according to results of fetal ultrasound examination.The differences of CTR and nuchal translucency thickness(NT)between the two groups were compared by t test.The area under the curve(AUC)was calculated by constructing the receiver operating curve(ROC)to determine the best diagnostic threshold,sensitivity and specificity of CTR and NT in predicting chromosomal abnormalities.Results:All the 86 fetuses had serious problems such as chromosome or gene abnormalities,or structural malformations.The CTR and NT of the structural malformation group were significantly higher than those of the non-structural malformation group,and the difference was statistically significant(P<0.05).Through villous biopsy of 60 fetuses,47 cases(78.3%,47/60)with haemoglobin Bart’s disease,10 cases(16.7%,10/60)with chromosomal abnormalities were detected,and none abnormalities were detected in other 3 cases.According to the ROC curve,the AUC for CTR and NT to predict chromosomal abnormalities are 0.691 and 0.954,respectively,and the diagnostic cut-off values are 0.57 and 3.6 mm,respectively.The sensitivity is 60.0%and 100%,the specificity is about 79.6%and 85.7%,respectively.Follow-up showed that 5 cases of fetal were death intrauterine,and the remaining 81 cases were induced to labor.The specificity of CTR increase in predicting adverse pregnancy outcome was 100%.Conclusion:The increase of CTR in 11-13+6 weeks of gestation indicates that the fetus may have serious problems and poor clinical prognosis.Attention should be paid to the accurate evaluation of CTR in early pregnancy so as to provide reference for
