目的探讨肺癌^(18)F-脱氧葡萄糖(FDG)PET 显像的标准摄取值(SUV)与病灶病理类型及肿瘤 T 分期间的关系。方法肺癌患者98例,皆行全身^(18)F-FDG PET 显像。肺癌病灶经2位有经验的医师目测确认后,沿病灶周边勾画感兴趣区,计算 SUV;病灶大...目的探讨肺癌^(18)F-脱氧葡萄糖(FDG)PET 显像的标准摄取值(SUV)与病灶病理类型及肿瘤 T 分期间的关系。方法肺癌患者98例,皆行全身^(18)F-FDG PET 显像。肺癌病灶经2位有经验的医师目测确认后,沿病灶周边勾画感兴趣区,计算 SUV;病灶大小:(长轴+短轴+纵轴)/3。结果肺腺癌组、鳞癌组、小细胞癌组、肺泡癌组及其他类型肺癌组 SUV 分别为4.4±2.1、5.4±2.8、4.4±1.3、2.5±0.7、4.7±1.2,肺泡癌组 SUV 较腺癌和鳞癌组低(P 均<0.05),其他各组间差异无显著性(P 均>0.05)。总体上,病灶的 SUV 与病灶大小无关(r=0.54,P>0.05),但当病灶≤3.0 cm时,肺癌病灶的 SUV 与病灶大小相关(r=0.63,P<0.01)。将病灶按大小分成≤1.5 cm 组、～3.0cm 组、～5.0 cm 组和>5.0 cm 组,各组间的 SUV 分别为2.3±0.8、3.6±1.1、4.8±1.6、5.1±1.5,组间差异有显著性(F=18.8,P<0.01),>3.0 cm 的两组间病灶 SUV 差异无显著性(P>0.05),其他各组间 SUV 差异均有显著性(P<0.01)。16例病灶 SUV<2.5者,主要为腺癌、肺泡癌和病灶<1.5cm 者。结论除肺泡癌外,肺癌病灶大小与病理类型无关;当病灶≤3.0 cm 时,病灶 SUV 与 T 分期有关;病灶越小,SUV 越小。展开更多
Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute viral hepatitis, a liver biopsy, though uncommonly performed, helps to rule out other nonviral cau...Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute viral hepatitis, a liver biopsy, though uncommonly performed, helps to rule out other nonviral causes of deranged liver function. In chronic viral hepatitis C, it is considered the gold standard in assessment of the degree of necroinflammation and the stage of fibrosis, to help guide treatment and determine prognosis. It also helps rule out any concomitant diseases such as steatohepatitis, hemochromatosis or others. In patients with chronic progressive liver disease with cirrhosis and dominant nodules, a targeted liver biopsy is helpful in differentiating a regenerative nodule from dysplastic nodule or hepatocellular carcinoma. In the setting of transplantation, the liver biopsy helps distinguish recurrent hepatitis C from acute rejection and also is invaluable in the diagnosis of fibrosing cholestatic hepatitis, a rare variant of recurrent hepatitis C. This comprehensive review discusses the entire spectrum of pathologic findings in the course of hepatitis C infection.展开更多
文摘目的探讨肺癌^(18)F-脱氧葡萄糖(FDG)PET 显像的标准摄取值(SUV)与病灶病理类型及肿瘤 T 分期间的关系。方法肺癌患者98例,皆行全身^(18)F-FDG PET 显像。肺癌病灶经2位有经验的医师目测确认后,沿病灶周边勾画感兴趣区,计算 SUV;病灶大小:(长轴+短轴+纵轴)/3。结果肺腺癌组、鳞癌组、小细胞癌组、肺泡癌组及其他类型肺癌组 SUV 分别为4.4±2.1、5.4±2.8、4.4±1.3、2.5±0.7、4.7±1.2,肺泡癌组 SUV 较腺癌和鳞癌组低(P 均<0.05),其他各组间差异无显著性(P 均>0.05)。总体上,病灶的 SUV 与病灶大小无关(r=0.54,P>0.05),但当病灶≤3.0 cm时,肺癌病灶的 SUV 与病灶大小相关(r=0.63,P<0.01)。将病灶按大小分成≤1.5 cm 组、～3.0cm 组、～5.0 cm 组和>5.0 cm 组,各组间的 SUV 分别为2.3±0.8、3.6±1.1、4.8±1.6、5.1±1.5,组间差异有显著性(F=18.8,P<0.01),>3.0 cm 的两组间病灶 SUV 差异无显著性(P>0.05),其他各组间 SUV 差异均有显著性(P<0.01)。16例病灶 SUV<2.5者,主要为腺癌、肺泡癌和病灶<1.5cm 者。结论除肺泡癌外,肺癌病灶大小与病理类型无关;当病灶≤3.0 cm 时,病灶 SUV 与 T 分期有关;病灶越小,SUV 越小。
文摘Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute viral hepatitis, a liver biopsy, though uncommonly performed, helps to rule out other nonviral causes of deranged liver function. In chronic viral hepatitis C, it is considered the gold standard in assessment of the degree of necroinflammation and the stage of fibrosis, to help guide treatment and determine prognosis. It also helps rule out any concomitant diseases such as steatohepatitis, hemochromatosis or others. In patients with chronic progressive liver disease with cirrhosis and dominant nodules, a targeted liver biopsy is helpful in differentiating a regenerative nodule from dysplastic nodule or hepatocellular carcinoma. In the setting of transplantation, the liver biopsy helps distinguish recurrent hepatitis C from acute rejection and also is invaluable in the diagnosis of fibrosing cholestatic hepatitis, a rare variant of recurrent hepatitis C. This comprehensive review discusses the entire spectrum of pathologic findings in the course of hepatitis C infection.
