This paper introduced the construction of the pumped-storage power station （PSPS）. In the excava- tion of underground power house, the principle of excavation in thin layer and support in time with real time monitor...This paper introduced the construction of the pumped-storage power station （PSPS）. In the excava- tion of underground power house, the principle of excavation in thin layer and support in time with real time monitoring are adopted. The excavation blasting parameters are adjusted timely. Through these, the excavation quality can be guaranteed, the surrounding rock can be prevented from being damaged and the deformation of power house side wall can be controlled. Five security defense lines have been adopted to solve anti-seepage and drainage in the major underground projects.展开更多
The paper is concerned with the Power System Protection schemes and the resulting design requirement that enhances stability as well as control with the implementation of TCP/IP. It discusses the architecture that upg...The paper is concerned with the Power System Protection schemes and the resulting design requirement that enhances stability as well as control with the implementation of TCP/IP. It discusses the architecture that upgrades the existing scheme by controlling all the control signals traffic between generating units, transmission system, connected loads and protection devices that are sensitive to control signals using TCP/IP and results are compared using Graphics User Interface (GUI) in MATLAB/Simulink. Protection system describes latest breakers circuit using indirect tripping command from generating units that protects load side through load breakers that receives action signal from local controllers that have a direct communication linkage with main server having strong data base, directly monitors everything through TCP/IP platform using GUI.展开更多
Studies have shown that targeting xanthine oxidase(XO)can be a feasible treatment for fructose-induced hyperuricemia and hyperglycemia.This study aimed to evaluate the dual regulatory effects and molecular mechanisms ...Studies have shown that targeting xanthine oxidase(XO)can be a feasible treatment for fructose-induced hyperuricemia and hyperglycemia.This study aimed to evaluate the dual regulatory effects and molecular mechanisms of diacylated anthocyanins from purple sweet potato(diacylated AF-PSPs)on hyperglycemia and hyperuricemia induced by a high-fructose/high-fat diet.The body weight,organ index,serum biochemical indexes,and liver antioxidant indexes of mice were measured,and the kidneys were observed in pathological sections.The relative expression levels of messenger RNAs(mRNAs)of fructose metabolism pathway enzymes in kidney were detected by fluorescent real-time quantitative polymerase chain(qPCR)reaction technique,and the expression of renal transporter protein and inflammatory factor pathway protein was determined by immunohistochemistry(IHC)technique.Results showed that diacylated AF-PSPs alleviated hyperuricemia in mice,and that this effect might be related to the regulation of liver XO activity,lipid accumulation,and relevant renal transporters.Diacylated AF-PSPs reduced body weight and relieved lipid metabolism disorder,liver lipid accumulation,and liver oxidative stress,thereby enhancing insulin utilization and sensitivity,lowering blood sugar,and reducing hyperglycemia in mice.Also,diacylated AF-PSPs restored mRNA levels related to renal fructose metabolism,and reduced kidney injury and inflammation.This study provided experimental evidence for the mechanisms of dual regulation of blood glucose and uric acid(UA)by diacylated AF-PSPs and their utilization as functional foods in the management of metabolic syndrome.展开更多
文摘This paper introduced the construction of the pumped-storage power station （PSPS）. In the excava- tion of underground power house, the principle of excavation in thin layer and support in time with real time monitoring are adopted. The excavation blasting parameters are adjusted timely. Through these, the excavation quality can be guaranteed, the surrounding rock can be prevented from being damaged and the deformation of power house side wall can be controlled. Five security defense lines have been adopted to solve anti-seepage and drainage in the major underground projects.
文摘The paper is concerned with the Power System Protection schemes and the resulting design requirement that enhances stability as well as control with the implementation of TCP/IP. It discusses the architecture that upgrades the existing scheme by controlling all the control signals traffic between generating units, transmission system, connected loads and protection devices that are sensitive to control signals using TCP/IP and results are compared using Graphics User Interface (GUI) in MATLAB/Simulink. Protection system describes latest breakers circuit using indirect tripping command from generating units that protects load side through load breakers that receives action signal from local controllers that have a direct communication linkage with main server having strong data base, directly monitors everything through TCP/IP platform using GUI.
基金supported by the National Key Technologies R&D Program of China(No.2021YFE0194000)the Fundamental Research Funds for the Central Universities of China(No.2662018PY022).
文摘Studies have shown that targeting xanthine oxidase(XO)can be a feasible treatment for fructose-induced hyperuricemia and hyperglycemia.This study aimed to evaluate the dual regulatory effects and molecular mechanisms of diacylated anthocyanins from purple sweet potato(diacylated AF-PSPs)on hyperglycemia and hyperuricemia induced by a high-fructose/high-fat diet.The body weight,organ index,serum biochemical indexes,and liver antioxidant indexes of mice were measured,and the kidneys were observed in pathological sections.The relative expression levels of messenger RNAs(mRNAs)of fructose metabolism pathway enzymes in kidney were detected by fluorescent real-time quantitative polymerase chain(qPCR)reaction technique,and the expression of renal transporter protein and inflammatory factor pathway protein was determined by immunohistochemistry(IHC)technique.Results showed that diacylated AF-PSPs alleviated hyperuricemia in mice,and that this effect might be related to the regulation of liver XO activity,lipid accumulation,and relevant renal transporters.Diacylated AF-PSPs reduced body weight and relieved lipid metabolism disorder,liver lipid accumulation,and liver oxidative stress,thereby enhancing insulin utilization and sensitivity,lowering blood sugar,and reducing hyperglycemia in mice.Also,diacylated AF-PSPs restored mRNA levels related to renal fructose metabolism,and reduced kidney injury and inflammation.This study provided experimental evidence for the mechanisms of dual regulation of blood glucose and uric acid(UA)by diacylated AF-PSPs and their utilization as functional foods in the management of metabolic syndrome.
