目的:探讨盆腔超声在特发性中枢性性早熟(Idiopathic central precocious puberty,ICPP)女童诊断中的临床应用价值。方法:回顾性分析我院及汕头潮南民生医院2019年1月至2020年1月20例采用盆腔超声诊断ICPP女童的临床资料,对临床及实验...目的:探讨盆腔超声在特发性中枢性性早熟(Idiopathic central precocious puberty,ICPP)女童诊断中的临床应用价值。方法:回顾性分析我院及汕头潮南民生医院2019年1月至2020年1月20例采用盆腔超声诊断ICPP女童的临床资料,对临床及实验室确诊为真性性早熟的20例女童与27例正常女童进行盆腔超声检查,检查其子宫上下径、前后径、左右径、容积,左右卵巢大小、容积、超过4mm的最大卵泡直径,将盆腔超声的测量数据做相关性分析并采用ROC曲线诊断其工作效能,计算其曲线下面积。结果:使用Mann-Whitney U法分析得出,真性性早熟组与正常组子宫、左右卵巢各项数值比较,均高于后者;相关性分析结果中得出,盆腔超声测量左右卵巢及子宫各数据结果呈现正相关,盆腔声检测子宫(上下径、前后径、左右径、容积)效能的AUC依次为0.985、0.822、0.967、0.831,敏感度依次为95%、80%、90%、85%,特异度依次为92.6%、77.8%、100%、70.4%;盆腔超声检测左卵巢(上下径、左右径、前后径、容积)效能AUC依次为0.976、0.805、0.946、0.784,敏感度依次为95%、75%、85%、50%,特异度依次为100%、74.1%、85.2%、100%;盆腔超声检测患者右卵巢(上下径、前后径、左右径、容积)AUC依次为0.991、0.839、0.983、0.828,敏感度依次为90%、75%、95%、60%,特异度依次为100%、77.8%、88.9%、96.3%,组间差异均具有统计学意义(P<0.05)。结论:盆腔超声诊断ICPP女童效能较高,值得为临床提供借鉴参考。展开更多
AIM： To investigate the expression and distribution of HBV in the ovaries and ova. METHODS： The immunohistochemistry method was used to detect the HBsAg and HBcAg in the ovaries of patients with chronic hepatitis B....AIM： To investigate the expression and distribution of HBV in the ovaries and ova. METHODS： The immunohistochemistry method was used to detect the HBsAg and HBcAg in the ovaries of patients with chronic hepatitis B. RESULTS： Expression of HBsAg in the ova, granular and interstitial cells of the ovaries was located in the cytomembrane and cytoplasm. Expression of HBcAg in the ova, granular, interstitial and endothelial cells of interstitial blood vessels of the ovaries was found in the cytomembrane, cytoplasm, and nuclei. CONCLUSION： HBV can infect the ova at different stages of development and replicate in it. 2005 The W3G Press and Elsevier Inc. All rights reserved.展开更多
Aims: Infertility is a major problem in our current societies and the Fertilia medical clinic in Bamako is a center for medical assistance in procreation (MAP) where there is an increasingly growing demand for ultraso...Aims: Infertility is a major problem in our current societies and the Fertilia medical clinic in Bamako is a center for medical assistance in procreation (MAP) where there is an increasingly growing demand for ultrasound. The objective of our study was to investigate the ultrasound causes likely to prevent the occurrence of pregnancy in a group of infertile and subfertile women. Subjects and Methods: This was a 5-year cross-sectional and prospective study, between January 2017 and January 2022, which involved 250 women wishing to become pregnant (infertile or subfertile), who came for pelvic ultrasound or follicular monitoring and who agreed to participate in our study. The parameters used were ultrasound reports including uterine, ovarian and tubal pathologies. It should be noted that in some cases no ultrasound cause of infertility was found. Data were entered and analyzed in SPSS. Results: 250 women were recruited into our. The average age was 32 years with extremes ranging from 17 to 51 years. 179 patients or 71.6% were between 17 and 35 years old. 139 patients or 55.6% had secondary infertility against 44.4% primary infertility. 202 patients or 80.8% had at least one ultrasound lesion and 48 patients or 19.2% had no significant ultrasound abnormality. The most represented ultrasound lesions were of uterine origin with 72.20%, 23.7% ovarian lesions and 04% tubal lesions. Uterine lesions were dominated by myomas, adenomyosis, endometrial polyps, uterine malformations and synechiae. As for ovarian lesions we noted cysts, polycystic ovary syndrome (PCOS), ovarian endometriosis, non-follicular ovaries and tubal ultrasound lesions showed unilateral or bilateral hydrosalpinx. Conclusion: In our study, ultrasound was an invaluable contribution to the diagnosis of the causes likely to explain subfertility and infertility in our respondents. She highlighted uterine, ovarian and tubal lesions, some of which could be corrected and pregnancies ensued.展开更多
文摘目的:探讨盆腔超声在特发性中枢性性早熟(Idiopathic central precocious puberty,ICPP)女童诊断中的临床应用价值。方法:回顾性分析我院及汕头潮南民生医院2019年1月至2020年1月20例采用盆腔超声诊断ICPP女童的临床资料,对临床及实验室确诊为真性性早熟的20例女童与27例正常女童进行盆腔超声检查,检查其子宫上下径、前后径、左右径、容积,左右卵巢大小、容积、超过4mm的最大卵泡直径,将盆腔超声的测量数据做相关性分析并采用ROC曲线诊断其工作效能,计算其曲线下面积。结果:使用Mann-Whitney U法分析得出,真性性早熟组与正常组子宫、左右卵巢各项数值比较,均高于后者;相关性分析结果中得出,盆腔超声测量左右卵巢及子宫各数据结果呈现正相关,盆腔声检测子宫(上下径、前后径、左右径、容积)效能的AUC依次为0.985、0.822、0.967、0.831,敏感度依次为95%、80%、90%、85%,特异度依次为92.6%、77.8%、100%、70.4%;盆腔超声检测左卵巢(上下径、左右径、前后径、容积)效能AUC依次为0.976、0.805、0.946、0.784,敏感度依次为95%、75%、85%、50%,特异度依次为100%、74.1%、85.2%、100%;盆腔超声检测患者右卵巢(上下径、前后径、左右径、容积)AUC依次为0.991、0.839、0.983、0.828,敏感度依次为90%、75%、95%、60%,特异度依次为100%、77.8%、88.9%、96.3%,组间差异均具有统计学意义(P<0.05)。结论:盆腔超声诊断ICPP女童效能较高,值得为临床提供借鉴参考。
基金Supported by the National Natural Science Foundation of China, No. 30371277
文摘AIM： To investigate the expression and distribution of HBV in the ovaries and ova. METHODS： The immunohistochemistry method was used to detect the HBsAg and HBcAg in the ovaries of patients with chronic hepatitis B. RESULTS： Expression of HBsAg in the ova, granular and interstitial cells of the ovaries was located in the cytomembrane and cytoplasm. Expression of HBcAg in the ova, granular, interstitial and endothelial cells of interstitial blood vessels of the ovaries was found in the cytomembrane, cytoplasm, and nuclei. CONCLUSION： HBV can infect the ova at different stages of development and replicate in it. 2005 The W3G Press and Elsevier Inc. All rights reserved.
文摘Aims: Infertility is a major problem in our current societies and the Fertilia medical clinic in Bamako is a center for medical assistance in procreation (MAP) where there is an increasingly growing demand for ultrasound. The objective of our study was to investigate the ultrasound causes likely to prevent the occurrence of pregnancy in a group of infertile and subfertile women. Subjects and Methods: This was a 5-year cross-sectional and prospective study, between January 2017 and January 2022, which involved 250 women wishing to become pregnant (infertile or subfertile), who came for pelvic ultrasound or follicular monitoring and who agreed to participate in our study. The parameters used were ultrasound reports including uterine, ovarian and tubal pathologies. It should be noted that in some cases no ultrasound cause of infertility was found. Data were entered and analyzed in SPSS. Results: 250 women were recruited into our. The average age was 32 years with extremes ranging from 17 to 51 years. 179 patients or 71.6% were between 17 and 35 years old. 139 patients or 55.6% had secondary infertility against 44.4% primary infertility. 202 patients or 80.8% had at least one ultrasound lesion and 48 patients or 19.2% had no significant ultrasound abnormality. The most represented ultrasound lesions were of uterine origin with 72.20%, 23.7% ovarian lesions and 04% tubal lesions. Uterine lesions were dominated by myomas, adenomyosis, endometrial polyps, uterine malformations and synechiae. As for ovarian lesions we noted cysts, polycystic ovary syndrome (PCOS), ovarian endometriosis, non-follicular ovaries and tubal ultrasound lesions showed unilateral or bilateral hydrosalpinx. Conclusion: In our study, ultrasound was an invaluable contribution to the diagnosis of the causes likely to explain subfertility and infertility in our respondents. She highlighted uterine, ovarian and tubal lesions, some of which could be corrected and pregnancies ensued.
