Introduction: Diabetes, a chronic disease characterized by persistent hyperglycemia, poses a major global health challenge. In Gabon, 10% of the population is affected by this condition, highlighting the need to activ...Introduction: Diabetes, a chronic disease characterized by persistent hyperglycemia, poses a major global health challenge. In Gabon, 10% of the population is affected by this condition, highlighting the need to actively understand and manage it. Ocular complications of diabetes, including diabetic retinopathy, glaucoma, and cataracts, have a devastating impact on patients quality of life and represent a crucial issue for healthcare systems. Methodology: This study conducted in Libreville from February 9, 2022, to April 15, 2022, was cross-sectional, longitudinal, and descriptive, with prospective data collection. Participants were diabetic patients regularly followed in the endocrinology department of CHUL, who were referred for a comprehensive ophthalmological examination at CHUO. Sampling was exhaustive, with strict inclusion criteria aimed at ensuring the representativeness of the study population. Results: The mean age of participants was 57.5 ± 13.2 years with a male-to-female ratio of 0.8. Personal histories were dominated by hypertension, while family histories were dominated by diabetes. Ocular complications of diabetes included refractive disorders (78.9%), cataracts (31.7%), glaucoma (78.9%), and diabetic retinopathy (13.7%). These ocular complications had a significant impact on participants’ quality of life, leading to impaired vision (78.9%), difficulties in carrying out daily activities (62.2%), the need for caregiver assistance (50.3%), high levels of stress and anxiety (68.9%), regular medication intake (71.4%), adherence to a specific diet (55.9%), and frequent blood glucose monitoring (74.5%). Conclusion: This study highlights the major impact of diabetic ocular complications on patients’ quality of life.展开更多
目的探讨翼状胬肉切除联合自体角膜缘干细胞移植手术对患者眼表及泪膜功能的影响。方法选取我院(2017年1月至2019年1月)收治的116例(116眼)翼状胬肉患者,根据不同治疗分为2组,对照组(n=58)接受翼状胬肉切除术治疗,观察组(n=58)在对照组...目的探讨翼状胬肉切除联合自体角膜缘干细胞移植手术对患者眼表及泪膜功能的影响。方法选取我院(2017年1月至2019年1月)收治的116例(116眼)翼状胬肉患者,根据不同治疗分为2组,对照组(n=58)接受翼状胬肉切除术治疗,观察组(n=58)在对照组基础上接受自体角膜缘干细胞移植手术治疗,对比2组患者手术前后视觉质量[角膜散光度(CAD)、裸眼视力(UCVA)]、泪膜破裂时间(BUT)、(泪液分泌SIt)试验、泪液羊齿状物试验(MFT)以及术后并发症(炎性反应、烧灼感、异物感、结膜充血)和胬肉复发率。结果手术前后2组患者CAD、UCVA对比无差异(P>0.05);术后7 d、30 d 2组患者CAD明显降低,UCVA明显升高(P<0.05)。手术前后2组患者SIt对比无差异(P>0.05);术后7 d对照组BUT明显低于观察组(P<0.05);2组患者术前和术后30 d BUT对比无差异(P>0.05)。术前2组患者MFT对比无差异(P>0.05);术后7 d、30 d 2组患者MFTⅠ、Ⅱ级比例明显增加,且观察组Ⅰ、Ⅱ级比例明显高于对照组(P<0.05)。2组患者术后均出现了流泪、眼痛等不适症状,1 d后减轻,术后7 d 2组患者并发症发生率和对比差异明显(P<0.05);随访1个月,2组患胬肉复发率对比差异明显(P<0.05)。结论翼状胬肉切除联合自体角膜缘干细胞移植手术对患者眼表及泪膜功能的具有积极的影响,能促进泪膜功能恢复,降低术后并发症和胬肉复发率。展开更多
Clinical manifestations of inflammatory bowel disease(IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual syste...Clinical manifestations of inflammatory bowel disease(IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual system is one of the most frequently affected, mainly by inflammatory disorders such as episcleritis, uveitis and scleritis. A critical review of available literature concerning ocular involvement in IBD, as it appears in Pub Med, was performed. Episcleritis, the most common ocular extraintestinal manifestation(EIM), seems to be more associated with IBD activity when compared with other ocular EIMs. In IBD patients, anterior uveitis has an insidious onset, it is longstanding and bilateral, and not related to the intestinal disease activity. Systemic steroids or immunosuppressants may be necessary in severe ocular inflammation cases, and control of the underlying bowel disease is important to prevent recurrence. Our review revealed that ocular involvement is more prevalent in Crohn's disease than ulcerative colitis, in active IBD, mainly in the presence of other EIMs. The ophthalmic symptoms in IBD are mainly nonspecific and their relevance may not be recognized by the clinician; most ophthalmic manifestations are treatable, and resolve without sequel upon prompt treatment. A collaborative clinical care team for management of IBD that includes ophthalmologists is central for improvement of quality care for these patients, and it is also cost-effective.展开更多
目的检索、评价并整合ICU俯卧位通气患者眼部并发症护理的相关证据,为临床实践提供参考。方法系统检索国内外相关指南网站、专业协会网站及BMJ Best Practice、UpToDate、Cochrane Library、澳大利亚乔安娜布里格斯研究所(Joanna Briggs...目的检索、评价并整合ICU俯卧位通气患者眼部并发症护理的相关证据,为临床实践提供参考。方法系统检索国内外相关指南网站、专业协会网站及BMJ Best Practice、UpToDate、Cochrane Library、澳大利亚乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)循证卫生保健中心数据库、PubMed、Web of Science、Science Direct、Embase、中国知网、万方数据库等关于ICU俯卧位通气患者眼部并发症护理的证据,文献类型包括临床实践指南、临床决策、证据总结、专家共识、团体标准、系统评价和范围审查,检索时限为2013年1月—2023年6月。指南由4名研究者独立进行质量评价,其余文献由2名研究者独立评价,对符合要求的文献提取证据并分级。结果共纳入文献15篇,包括6篇指南、2篇临床决策、2篇证据总结、3篇系统评价、1篇范围审查和1篇团体标准,从组织与培训、风险识别、眼部评估、眼部保护、体位管理、定期观察6个方面共总结了16条证据。结论该研究总结了ICU俯卧位通气患者眼部并发症护理的最佳证据,ICU医护人员应结合临床情境,选择有针对性的证据对俯卧位患者进行眼部保护,从而降低眼部并发症的发生率,提高患者生存质量。展开更多
Objectives: To assess the factors influencing the ophthalmological follow-up of sickle cell patients in Togo. Materials and Methods: The national center of research and care for sickle cell patients (CNRSD) served as ...Objectives: To assess the factors influencing the ophthalmological follow-up of sickle cell patients in Togo. Materials and Methods: The national center of research and care for sickle cell patients (CNRSD) served as study setting. It was a descriptive and analytical study by interview over a three-month period from December 01, 2020 to March 02, 2021. Was included in the study, any patient with sickle cell disease genotype SS or SC, age ≥ 17 years, regularly followed at the CNRSD and having accepted the interview by a survey sheet. Excluded were patients with sickle cell trait genotype AS or AC or with a disability that prevented them from being interviewed. Results: Two hundred and fifty (250) patients with sickle cell disease were interviewed. The mean age was 29.1 years ± 11.12 years [17 years;67 years] and the sex ratio = 0.52. Nine patients over ten (9/10) attended at least secondary school. The jobless represented 25.60% of the total population followed respectively by students and laborers in 20.40% and 16% of cases. Twenty-four percent (24%) of patients were followed up in ophthalmology department. Statistically, there was no significant relationship between level of education (p = 0.4083), occupation (p = 0.6441) and knowledge of the ocular complications of sickle cell disease. Statistically, there was a significant relationship between knowledge of the ocular complications of sickle cell disease and compliance with ophthalmological follow-up (p = 0.0009). Conclusion: The knowledge of eye disorders related to sickle cell disease by patients with sickle cell disease improves their ophthalmological follow-up. Greater awareness on eye disorders related to sickle cell disease by medical staff towards patients with sickle cell disease would improve ophthalmological follow-up. .展开更多
文摘Introduction: Diabetes, a chronic disease characterized by persistent hyperglycemia, poses a major global health challenge. In Gabon, 10% of the population is affected by this condition, highlighting the need to actively understand and manage it. Ocular complications of diabetes, including diabetic retinopathy, glaucoma, and cataracts, have a devastating impact on patients quality of life and represent a crucial issue for healthcare systems. Methodology: This study conducted in Libreville from February 9, 2022, to April 15, 2022, was cross-sectional, longitudinal, and descriptive, with prospective data collection. Participants were diabetic patients regularly followed in the endocrinology department of CHUL, who were referred for a comprehensive ophthalmological examination at CHUO. Sampling was exhaustive, with strict inclusion criteria aimed at ensuring the representativeness of the study population. Results: The mean age of participants was 57.5 ± 13.2 years with a male-to-female ratio of 0.8. Personal histories were dominated by hypertension, while family histories were dominated by diabetes. Ocular complications of diabetes included refractive disorders (78.9%), cataracts (31.7%), glaucoma (78.9%), and diabetic retinopathy (13.7%). These ocular complications had a significant impact on participants’ quality of life, leading to impaired vision (78.9%), difficulties in carrying out daily activities (62.2%), the need for caregiver assistance (50.3%), high levels of stress and anxiety (68.9%), regular medication intake (71.4%), adherence to a specific diet (55.9%), and frequent blood glucose monitoring (74.5%). Conclusion: This study highlights the major impact of diabetic ocular complications on patients’ quality of life.
文摘目的探讨翼状胬肉切除联合自体角膜缘干细胞移植手术对患者眼表及泪膜功能的影响。方法选取我院(2017年1月至2019年1月)收治的116例(116眼)翼状胬肉患者,根据不同治疗分为2组,对照组(n=58)接受翼状胬肉切除术治疗,观察组(n=58)在对照组基础上接受自体角膜缘干细胞移植手术治疗,对比2组患者手术前后视觉质量[角膜散光度(CAD)、裸眼视力(UCVA)]、泪膜破裂时间(BUT)、(泪液分泌SIt)试验、泪液羊齿状物试验(MFT)以及术后并发症(炎性反应、烧灼感、异物感、结膜充血)和胬肉复发率。结果手术前后2组患者CAD、UCVA对比无差异(P>0.05);术后7 d、30 d 2组患者CAD明显降低,UCVA明显升高(P<0.05)。手术前后2组患者SIt对比无差异(P>0.05);术后7 d对照组BUT明显低于观察组(P<0.05);2组患者术前和术后30 d BUT对比无差异(P>0.05)。术前2组患者MFT对比无差异(P>0.05);术后7 d、30 d 2组患者MFTⅠ、Ⅱ级比例明显增加,且观察组Ⅰ、Ⅱ级比例明显高于对照组(P<0.05)。2组患者术后均出现了流泪、眼痛等不适症状,1 d后减轻,术后7 d 2组患者并发症发生率和对比差异明显(P<0.05);随访1个月,2组患胬肉复发率对比差异明显(P<0.05)。结论翼状胬肉切除联合自体角膜缘干细胞移植手术对患者眼表及泪膜功能的具有积极的影响,能促进泪膜功能恢复,降低术后并发症和胬肉复发率。
文摘Clinical manifestations of inflammatory bowel disease(IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual system is one of the most frequently affected, mainly by inflammatory disorders such as episcleritis, uveitis and scleritis. A critical review of available literature concerning ocular involvement in IBD, as it appears in Pub Med, was performed. Episcleritis, the most common ocular extraintestinal manifestation(EIM), seems to be more associated with IBD activity when compared with other ocular EIMs. In IBD patients, anterior uveitis has an insidious onset, it is longstanding and bilateral, and not related to the intestinal disease activity. Systemic steroids or immunosuppressants may be necessary in severe ocular inflammation cases, and control of the underlying bowel disease is important to prevent recurrence. Our review revealed that ocular involvement is more prevalent in Crohn's disease than ulcerative colitis, in active IBD, mainly in the presence of other EIMs. The ophthalmic symptoms in IBD are mainly nonspecific and their relevance may not be recognized by the clinician; most ophthalmic manifestations are treatable, and resolve without sequel upon prompt treatment. A collaborative clinical care team for management of IBD that includes ophthalmologists is central for improvement of quality care for these patients, and it is also cost-effective.
文摘目的检索、评价并整合ICU俯卧位通气患者眼部并发症护理的相关证据,为临床实践提供参考。方法系统检索国内外相关指南网站、专业协会网站及BMJ Best Practice、UpToDate、Cochrane Library、澳大利亚乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)循证卫生保健中心数据库、PubMed、Web of Science、Science Direct、Embase、中国知网、万方数据库等关于ICU俯卧位通气患者眼部并发症护理的证据,文献类型包括临床实践指南、临床决策、证据总结、专家共识、团体标准、系统评价和范围审查,检索时限为2013年1月—2023年6月。指南由4名研究者独立进行质量评价,其余文献由2名研究者独立评价,对符合要求的文献提取证据并分级。结果共纳入文献15篇,包括6篇指南、2篇临床决策、2篇证据总结、3篇系统评价、1篇范围审查和1篇团体标准,从组织与培训、风险识别、眼部评估、眼部保护、体位管理、定期观察6个方面共总结了16条证据。结论该研究总结了ICU俯卧位通气患者眼部并发症护理的最佳证据,ICU医护人员应结合临床情境,选择有针对性的证据对俯卧位患者进行眼部保护,从而降低眼部并发症的发生率,提高患者生存质量。
文摘Objectives: To assess the factors influencing the ophthalmological follow-up of sickle cell patients in Togo. Materials and Methods: The national center of research and care for sickle cell patients (CNRSD) served as study setting. It was a descriptive and analytical study by interview over a three-month period from December 01, 2020 to March 02, 2021. Was included in the study, any patient with sickle cell disease genotype SS or SC, age ≥ 17 years, regularly followed at the CNRSD and having accepted the interview by a survey sheet. Excluded were patients with sickle cell trait genotype AS or AC or with a disability that prevented them from being interviewed. Results: Two hundred and fifty (250) patients with sickle cell disease were interviewed. The mean age was 29.1 years ± 11.12 years [17 years;67 years] and the sex ratio = 0.52. Nine patients over ten (9/10) attended at least secondary school. The jobless represented 25.60% of the total population followed respectively by students and laborers in 20.40% and 16% of cases. Twenty-four percent (24%) of patients were followed up in ophthalmology department. Statistically, there was no significant relationship between level of education (p = 0.4083), occupation (p = 0.6441) and knowledge of the ocular complications of sickle cell disease. Statistically, there was a significant relationship between knowledge of the ocular complications of sickle cell disease and compliance with ophthalmological follow-up (p = 0.0009). Conclusion: The knowledge of eye disorders related to sickle cell disease by patients with sickle cell disease improves their ophthalmological follow-up. Greater awareness on eye disorders related to sickle cell disease by medical staff towards patients with sickle cell disease would improve ophthalmological follow-up. .
