This paper describes the application of reliability-centered maintenance methodology to the development of maintenance plan for a steam-process plant. The main objective of reliability-centered maintenance is the cost...This paper describes the application of reliability-centered maintenance methodology to the development of maintenance plan for a steam-process plant. The main objective of reliability-centered maintenance is the cost-effective maintenance of the plant components inherent reliability value. The process-steam plant consists of fire-tube boiler, steam distribution, dryer, feed-water pump and process heater. Within this context, a maintenance program for the plant is carried out based on this reliability-centered maintenance concept. Applying of the reliability-centered maintenance methodology showed that the main time between failures for the plant equipments and the probability of sudden equipment failures are decreased. The proposed labor program is carried out. The results show that the labor cost decreases from 295200 $/year to 220800 $/year (about 25.8% of the total labor cost) for the proposed preventive maintenance planning. Moreover, the downtime cost of the plant components is investigated. The proposed PM planning results indicate a saving of about 80% of the total downtime cost as compared with that of current maintenance. In addition, the proposed spare parts programs for the plant components are generated. The results show that about 22.17% of the annual spare parts cost are saved when proposed preventive maintenance planning other current maintenance once. Based on these results, the application of the predictive maintenance should be applied.展开更多
The criticality of transformers and reactors in the power transmission network and the paramount importance of ensuring their reliability through maintenance of the insulating oil is known. This paper presents a compr...The criticality of transformers and reactors in the power transmission network and the paramount importance of ensuring their reliability through maintenance of the insulating oil is known. This paper presents a comprehensive examination of the efficacy and economic viability of a dielectric oil regeneration system, as implemented by the Transmission System Maintenance Department (TSMD) of the Independent Power Transmission Operator (IPTO), Greece’s sole transmission operator. Through a detailed chemical analysis and performance evaluation, we assess the impact of the regeneration system on treated insulating oil quality over multiple cycles. The study reveals that the electrical properties of the insulating oil are fully restored after regeneration, negating the need to fully replace it, while the investment becomes cost-neutral within weeks from the commissioning of the regeneration system. This economic analysis, coupled with the system’s environmental benefits of reducing waste oil generation, positions the dielectric oil regeneration system as a compelling solution for the maintenance of power transmission assets.展开更多
BACKGROUND Blastic plasmacytoid dendritic cell neoplasm(BPDCN)is a rare,highly invasive malignant neoplasm.There is no universally accepted standard of care because of its rarity and the dearth of prospective research...BACKGROUND Blastic plasmacytoid dendritic cell neoplasm(BPDCN)is a rare,highly invasive malignant neoplasm.There is no universally accepted standard of care because of its rarity and the dearth of prospective research.It is still challenging for some patients to achieve persistent clinical remission or cure,despite the success of allogeneic hematopoietic stem cell transplantation(allo-HSCT),indicating that there is still a significant recurrence rate.We report a case of prevention of BPDCN allograft recurrence by azacitidine maintenance therapy and review the relevant literature.CASE SUMMARY We report a 41-year-old man with BPDCN who was admitted to hospital due to skin sclerosis for>5 mo’duration.BPDCN was diagnosed by combined clinical assessment and laboratory examinations.Following diagnosis,the patients underwent induction consolidation chemotherapy to achieve the first complete remission,followed by bridging allo-HSCT.Post-transplantation,azacitidine(75 mg/m2 for 7 d)was administered as maintenance therapy,with repeat administration every 4–6 wk and appropriate extension of the chemotherapy cycle.After 10 cycles,the patient has been disease free for 26 mo after transplantation.Regular assessments of bone marrow morphology,minimal residual disease,full donor chimerism,Epstein–Barr virus,and cytomegalovirus all yielded normal results with no abnormalities detected.CONCLUSION Azacitidine may be a safe and effective maintenance treatment for BPDCN following transplantation because there were no overt adverse events during the course of treatment.展开更多
文摘This paper describes the application of reliability-centered maintenance methodology to the development of maintenance plan for a steam-process plant. The main objective of reliability-centered maintenance is the cost-effective maintenance of the plant components inherent reliability value. The process-steam plant consists of fire-tube boiler, steam distribution, dryer, feed-water pump and process heater. Within this context, a maintenance program for the plant is carried out based on this reliability-centered maintenance concept. Applying of the reliability-centered maintenance methodology showed that the main time between failures for the plant equipments and the probability of sudden equipment failures are decreased. The proposed labor program is carried out. The results show that the labor cost decreases from 295200 $/year to 220800 $/year (about 25.8% of the total labor cost) for the proposed preventive maintenance planning. Moreover, the downtime cost of the plant components is investigated. The proposed PM planning results indicate a saving of about 80% of the total downtime cost as compared with that of current maintenance. In addition, the proposed spare parts programs for the plant components are generated. The results show that about 22.17% of the annual spare parts cost are saved when proposed preventive maintenance planning other current maintenance once. Based on these results, the application of the predictive maintenance should be applied.
文摘The criticality of transformers and reactors in the power transmission network and the paramount importance of ensuring their reliability through maintenance of the insulating oil is known. This paper presents a comprehensive examination of the efficacy and economic viability of a dielectric oil regeneration system, as implemented by the Transmission System Maintenance Department (TSMD) of the Independent Power Transmission Operator (IPTO), Greece’s sole transmission operator. Through a detailed chemical analysis and performance evaluation, we assess the impact of the regeneration system on treated insulating oil quality over multiple cycles. The study reveals that the electrical properties of the insulating oil are fully restored after regeneration, negating the need to fully replace it, while the investment becomes cost-neutral within weeks from the commissioning of the regeneration system. This economic analysis, coupled with the system’s environmental benefits of reducing waste oil generation, positions the dielectric oil regeneration system as a compelling solution for the maintenance of power transmission assets.
文摘BACKGROUND Blastic plasmacytoid dendritic cell neoplasm(BPDCN)is a rare,highly invasive malignant neoplasm.There is no universally accepted standard of care because of its rarity and the dearth of prospective research.It is still challenging for some patients to achieve persistent clinical remission or cure,despite the success of allogeneic hematopoietic stem cell transplantation(allo-HSCT),indicating that there is still a significant recurrence rate.We report a case of prevention of BPDCN allograft recurrence by azacitidine maintenance therapy and review the relevant literature.CASE SUMMARY We report a 41-year-old man with BPDCN who was admitted to hospital due to skin sclerosis for>5 mo’duration.BPDCN was diagnosed by combined clinical assessment and laboratory examinations.Following diagnosis,the patients underwent induction consolidation chemotherapy to achieve the first complete remission,followed by bridging allo-HSCT.Post-transplantation,azacitidine(75 mg/m2 for 7 d)was administered as maintenance therapy,with repeat administration every 4–6 wk and appropriate extension of the chemotherapy cycle.After 10 cycles,the patient has been disease free for 26 mo after transplantation.Regular assessments of bone marrow morphology,minimal residual disease,full donor chimerism,Epstein–Barr virus,and cytomegalovirus all yielded normal results with no abnormalities detected.CONCLUSION Azacitidine may be a safe and effective maintenance treatment for BPDCN following transplantation because there were no overt adverse events during the course of treatment.
