状态估计作为能量管理系统(EMS)和实时电力市场的基础和核心,正在变得日益重要。该文从信息科学的新视角,对电力系统状态估计的数学基础进行了研究。根据最小信息损失(MIL)决策原理,提出了能够适用于各种概率分布的通用的 MIL 状态估计...状态估计作为能量管理系统(EMS)和实时电力市场的基础和核心,正在变得日益重要。该文从信息科学的新视角,对电力系统状态估计的数学基础进行了研究。根据最小信息损失(MIL)决策原理,提出了能够适用于各种概率分布的通用的 MIL 状态估计新原理。并在理论上证明了加权最加权最小二乘(WLAV)估计法都是MIL 状态估计的特例,将传统状态估计方法在信息学的意义上统一起来,赋予了传统状态估计方法全新的信息学内涵。在 MIL 意义上,针对次输电系统和配电系统状态估计中普遍采用的电流幅值量测,得到了大电流是 WLS 估计法的近似条件。用算例比较了 MIL 和 WLS 状态估计的估计结果,进一步验证了 WLS 法在非正态分布时的近似条件。展开更多
1 Summary The 2015 Nobel Prize in Physiology or Medicine was awarded to Professor Tu YouYou for her key contributions to the discovery of artemisinin. Artemisinin has saved mil- lions of lives and represents one of t...1 Summary The 2015 Nobel Prize in Physiology or Medicine was awarded to Professor Tu YouYou for her key contributions to the discovery of artemisinin. Artemisinin has saved mil- lions of lives and represents one of the significant contribu- tions of China to global health. Many scientists were in- volved in the previously unknown 523 Project, and the No- bel Prize given to a single person has not been without con- troversy. Here we summarize some key events in the 523 Project and present our views on the Award to help the pub- lic better understand the rationale of the Nobel Committee' s decision, the significance of the discovery, and current is- sues related to artimisinin in treating malaria.展开更多
The generation of mature and healthy oocytes is the most critical event in the entire female reproductive process,and the mechanisms regulating this process remain to be studied.Here,we demonstrate that Smith-like(LSM...The generation of mature and healthy oocytes is the most critical event in the entire female reproductive process,and the mechanisms regulating this process remain to be studied.Here,we demonstrate that Smith-like(LSM)family member 14B(LSM14B)regulates oocyte maturation,and the loss of LSM14B in mouse ovaries leads to abnormal oocyte MII arrest and female infertility.Next,we find the aberrant transcriptional activation,indicated by abnormal non-surrounded nucleolus and surrounded nucleolus oocyte proportions,and abnormal chromosome assembly and segregation in Lsm14b-deficient mouse oocytes.The global transcriptome analysis suggests that many transcripts involved in cytoplasmic processing body(P-body)function are altered in Lsm14b-deficient mouse oocytes.Deletion of Lsm14b results in the expression and/or localization changes of P-body components(such as LSM14A,DCP1A,and 4E-T).Notably,DDX6,a key component of the P-body,is downregulated and accumulates in the nuclei in Lsm14b-deficient mouse oocytes.Taken together,our data suggest that LSM14B links mouse oocyte maturation to female fertility through the regulation of the P-body.展开更多
Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "...Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "4453" effects, as fol ows: "Four increases" include to increase loosen soil quantity in cultivation layers, soil nutri-ents use, "water pool" in soils, and "oxygen pool" in soils. Four reductions are to reduce soil erosion, carbon emission, salt content and heavy metal in soils. Five resistances refer to improve crop resistance capacity in terms of drought, high tem-perature, lower temperature, disease and lodging. Three improvements indicate to enhance photosynthetic efficiency over 10%, yield in 10%-30% and quality over 5%. lt is researched that without additional chemical fertilizer, yield could increase by 10% by labor force, animal, tractor or smash-ridging machine. What’s more, by smash-ridging cultivation, the depth can be 20 times or higher compared with tractor cultivation, with looser soils. lt is estimated that if smash-ridging cultivation is applied once in agricultural lands in China, present soil layers can be twice as deep as present. Specifical y, the thickness of loose soil-layers could be extended from 10-18 cm at present to 25-35 cm, and natural rainfal would increase by 40 bil ion cm3. After vitalization of soil nutrients, chemical fertilizer would decrease by 7 bil ion kg, and the increased c rops would feed more than 300 mil ion population as per yield at 7 50 kg/hm2.展开更多
文摘状态估计作为能量管理系统(EMS)和实时电力市场的基础和核心,正在变得日益重要。该文从信息科学的新视角,对电力系统状态估计的数学基础进行了研究。根据最小信息损失(MIL)决策原理,提出了能够适用于各种概率分布的通用的 MIL 状态估计新原理。并在理论上证明了加权最加权最小二乘(WLAV)估计法都是MIL 状态估计的特例,将传统状态估计方法在信息学的意义上统一起来,赋予了传统状态估计方法全新的信息学内涵。在 MIL 意义上,针对次输电系统和配电系统状态估计中普遍采用的电流幅值量测,得到了大电流是 WLS 估计法的近似条件。用算例比较了 MIL 和 WLS 状态估计的估计结果,进一步验证了 WLS 法在非正态分布时的近似条件。
基金supported by the Division of Intramural Research at the National Institute of Allergy and Infectious Diseases(NIAID)
文摘1 Summary The 2015 Nobel Prize in Physiology or Medicine was awarded to Professor Tu YouYou for her key contributions to the discovery of artemisinin. Artemisinin has saved mil- lions of lives and represents one of the significant contribu- tions of China to global health. Many scientists were in- volved in the previously unknown 523 Project, and the No- bel Prize given to a single person has not been without con- troversy. Here we summarize some key events in the 523 Project and present our views on the Award to help the pub- lic better understand the rationale of the Nobel Committee' s decision, the significance of the discovery, and current is- sues related to artimisinin in treating malaria.
基金supported by the National Key R&D Program of China(2021YFC2700201 to X.W.)the National Natural Science Foundation of China(32070831,32270897 to X.W.).
文摘The generation of mature and healthy oocytes is the most critical event in the entire female reproductive process,and the mechanisms regulating this process remain to be studied.Here,we demonstrate that Smith-like(LSM)family member 14B(LSM14B)regulates oocyte maturation,and the loss of LSM14B in mouse ovaries leads to abnormal oocyte MII arrest and female infertility.Next,we find the aberrant transcriptional activation,indicated by abnormal non-surrounded nucleolus and surrounded nucleolus oocyte proportions,and abnormal chromosome assembly and segregation in Lsm14b-deficient mouse oocytes.The global transcriptome analysis suggests that many transcripts involved in cytoplasmic processing body(P-body)function are altered in Lsm14b-deficient mouse oocytes.Deletion of Lsm14b results in the expression and/or localization changes of P-body components(such as LSM14A,DCP1A,and 4E-T).Notably,DDX6,a key component of the P-body,is downregulated and accumulates in the nuclei in Lsm14b-deficient mouse oocytes.Taken together,our data suggest that LSM14B links mouse oocyte maturation to female fertility through the regulation of the P-body.
基金Supported by the Key Project of Science and Technology of Guangxi(1222014-2C)Achievements Transformation Project of Guangxi Academy of Agricultural Science and Technology(201405)Fundamental Research Funds for Guangxi Academy of Agricultural Science and Technology(2014YZ07)~~
文摘Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "4453" effects, as fol ows: "Four increases" include to increase loosen soil quantity in cultivation layers, soil nutri-ents use, "water pool" in soils, and "oxygen pool" in soils. Four reductions are to reduce soil erosion, carbon emission, salt content and heavy metal in soils. Five resistances refer to improve crop resistance capacity in terms of drought, high tem-perature, lower temperature, disease and lodging. Three improvements indicate to enhance photosynthetic efficiency over 10%, yield in 10%-30% and quality over 5%. lt is researched that without additional chemical fertilizer, yield could increase by 10% by labor force, animal, tractor or smash-ridging machine. What’s more, by smash-ridging cultivation, the depth can be 20 times or higher compared with tractor cultivation, with looser soils. lt is estimated that if smash-ridging cultivation is applied once in agricultural lands in China, present soil layers can be twice as deep as present. Specifical y, the thickness of loose soil-layers could be extended from 10-18 cm at present to 25-35 cm, and natural rainfal would increase by 40 bil ion cm3. After vitalization of soil nutrients, chemical fertilizer would decrease by 7 bil ion kg, and the increased c rops would feed more than 300 mil ion population as per yield at 7 50 kg/hm2.