Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic inf...Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.展开更多
目的分析1990—2019年中国喉癌疾病负担的变化趋势。方法基于全球疾病负担研究数据库对比分析1990—2019年我国和全球喉癌的发病率、死亡率、伤残调整寿命年(disability adjusted life years,DALYs)、过早死亡损失寿命年、伤残损失寿命...目的分析1990—2019年中国喉癌疾病负担的变化趋势。方法基于全球疾病负担研究数据库对比分析1990—2019年我国和全球喉癌的发病率、死亡率、伤残调整寿命年(disability adjusted life years,DALYs)、过早死亡损失寿命年、伤残损失寿命年及年估计变化百分比(estimated annual percentage change,EAPC),并进一步分析我国不同年龄、性别及喉癌归因危险因素的疾病负担情况。结果2019年中国喉癌发病例数、死亡例数和DALYs分别为4.54万、2.03万和49.79万人年,比1990年分别增加了221.98%、76.20%和56.72%。1990—2019年中国喉癌标化发病率呈上升趋势(EAPC=1.32),而标化死亡率(EAPC=-0.96)和标化DALYs率(EAPC=-1.21)均呈下降趋势。我国喉癌的发病、死亡和疾病负担在50~69岁年龄组开始明显上升,≥70岁达到最高,且男性显著高于女性。与1990年相比,2019年我国可归因于吸烟、饮酒和石棉暴露的喉癌死亡比例和DALYs比例均有所增加;可归因于硫酸暴露的喉癌死亡比例和DALYs比例均有所下降。结论1990—2019年我国喉癌的标化发病率呈上升趋势,而标化死亡率和标化DALYs率均呈下降趋势,疾病负担在男性中明显高于女性,中老年人群的疾病负担仍较为沉重,提示仍需进一步加强喉癌的防治工作。展开更多
Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to Ma...Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.展开更多
目的观察针刺对喉癌术后放疗后吞咽障碍患者吞咽功能、营养状态及生活质量的影响。方法将58例喉癌术后放疗后吞咽障碍患者随机分为试验组和对照组,每组29例。对照组采用康复治疗,试验组在对照组基础上采用针刺治疗。治疗前后采用吞咽造...目的观察针刺对喉癌术后放疗后吞咽障碍患者吞咽功能、营养状态及生活质量的影响。方法将58例喉癌术后放疗后吞咽障碍患者随机分为试验组和对照组,每组29例。对照组采用康复治疗,试验组在对照组基础上采用针刺治疗。治疗前后采用吞咽造影检查(videofluoroscopic swallowing examination,VFSE)评价吞咽功能,患者参与的主观全面评定(patient-generated subjective global assessment,PG-SGA)评价营养状态,生活质量调查表(quality of life questionnaire-core 30,QLQ-C30)评价生活质量。结果治疗后,试验组VFSE、PG-SGA和QLQ-C30评分较治疗前改善(P<0.05);对照组VFSE和QLQ-C30评分均较治疗前改善(P<0.05);试验组VFSE、PG-SGA和QLQ-C30评分优于对照组(P<0.05)。试验组治疗前后VFSE、PG-SGA和QLQ-C30评分差值优于对照组(P<0.05)。结论在康复治疗的基础上,针刺可有效改善喉癌术后放疗后吞咽障碍患者的吞咽功能和营养状态,提高患者的生活质量。展开更多
文摘Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.
文摘Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.
文摘目的观察针刺对喉癌术后放疗后吞咽障碍患者吞咽功能、营养状态及生活质量的影响。方法将58例喉癌术后放疗后吞咽障碍患者随机分为试验组和对照组,每组29例。对照组采用康复治疗,试验组在对照组基础上采用针刺治疗。治疗前后采用吞咽造影检查(videofluoroscopic swallowing examination,VFSE)评价吞咽功能,患者参与的主观全面评定(patient-generated subjective global assessment,PG-SGA)评价营养状态,生活质量调查表(quality of life questionnaire-core 30,QLQ-C30)评价生活质量。结果治疗后,试验组VFSE、PG-SGA和QLQ-C30评分较治疗前改善(P<0.05);对照组VFSE和QLQ-C30评分均较治疗前改善(P<0.05);试验组VFSE、PG-SGA和QLQ-C30评分优于对照组(P<0.05)。试验组治疗前后VFSE、PG-SGA和QLQ-C30评分差值优于对照组(P<0.05)。结论在康复治疗的基础上,针刺可有效改善喉癌术后放疗后吞咽障碍患者的吞咽功能和营养状态,提高患者的生活质量。
