The gut microbiota of Mongolian hosts has distinctive characteristics due to their meat- and dairyoriented daily diets and unique genotype.The aim of the present study was to investigate the effect of switching from t...The gut microbiota of Mongolian hosts has distinctive characteristics due to their meat- and dairyoriented daily diets and unique genotype.The aim of the present study was to investigate the effect of switching from the typical high protein and fat Mongolian diets to carbohydrate-rich meals composed principally of wheat,rice and naked oats on the host gut microbiota within 3 weeks.Our study took the advantage of the long sequence reads produced by the Pac Bio single molecule real-time sequencing technology to enable the profiling of subjects' gut microbiota communities along the diet intervention to the species precision.We found that the bacterial richness and diversity decreased apparently along the diet intervention.During the diet intervention,the gut microbiota composition displayed no significant difference at phylum level(with major phyla of Firmicutes,Bacteroidetes,Tenericutes and Proteobacteria).The relative abundances of some genera such as Bacteroidetes,Faecalibacterium,Roseburia,Alistipes,Streptococcus,and Oscillospira were significantly altered after the diet switching started.Notably,significant changes were also observed in the proportions of the species Bacteroides dorei,Bacteroides fragilis,Bacteroides thetaiotaomicron,Ruminococcus albus,Ruminococcus faecis,Roseburia faecis and Eubacterium ventriosum.These results have demonstrated that diet and host gut microbiota is closely linked.展开更多
目的:探讨应用不同干预时间中药热奄包对经外周中心静脉置管(Peripherally inserted central catheter,PICC)术后机械性静脉炎的影响。方法:将100例PICC术后机械性静脉炎患者随机分为观察组和对照组,每组50例。两组均由PICC认证的专科...目的:探讨应用不同干预时间中药热奄包对经外周中心静脉置管(Peripherally inserted central catheter,PICC)术后机械性静脉炎的影响。方法:将100例PICC术后机械性静脉炎患者随机分为观察组和对照组,每组50例。两组均由PICC认证的专科护士进行置管操作,在PICC置管术后均被给予常规护理,观察组应用中药热奄包连续热敷3天,对照组应用热奄包连续热敷5天,比较两组患者机械性静脉炎的发生率,穿刺手臂出血、肿胀及疼痛的情况。结果:机械性静脉炎发生率观察组[2.08%(1/48)]与对照组[0.00%(0/50)]比较,差异无统计学意义(P>0.05)。两组手臂疼痛程度、肿胀程度比较,差异无统计学差异(P>0.05)。观察组较对照组穿刺处出血少(P<0.05)。结论:PICC术后应用中药热奄包热敷3天即能有效预防机械性静脉炎,并可减轻穿刺引起的手臂疼痛、肿胀等早期不适症状,减少术后出血的风险。展开更多
文摘The gut microbiota of Mongolian hosts has distinctive characteristics due to their meat- and dairyoriented daily diets and unique genotype.The aim of the present study was to investigate the effect of switching from the typical high protein and fat Mongolian diets to carbohydrate-rich meals composed principally of wheat,rice and naked oats on the host gut microbiota within 3 weeks.Our study took the advantage of the long sequence reads produced by the Pac Bio single molecule real-time sequencing technology to enable the profiling of subjects' gut microbiota communities along the diet intervention to the species precision.We found that the bacterial richness and diversity decreased apparently along the diet intervention.During the diet intervention,the gut microbiota composition displayed no significant difference at phylum level(with major phyla of Firmicutes,Bacteroidetes,Tenericutes and Proteobacteria).The relative abundances of some genera such as Bacteroidetes,Faecalibacterium,Roseburia,Alistipes,Streptococcus,and Oscillospira were significantly altered after the diet switching started.Notably,significant changes were also observed in the proportions of the species Bacteroides dorei,Bacteroides fragilis,Bacteroides thetaiotaomicron,Ruminococcus albus,Ruminococcus faecis,Roseburia faecis and Eubacterium ventriosum.These results have demonstrated that diet and host gut microbiota is closely linked.
文摘目的:探讨应用不同干预时间中药热奄包对经外周中心静脉置管(Peripherally inserted central catheter,PICC)术后机械性静脉炎的影响。方法:将100例PICC术后机械性静脉炎患者随机分为观察组和对照组,每组50例。两组均由PICC认证的专科护士进行置管操作,在PICC置管术后均被给予常规护理,观察组应用中药热奄包连续热敷3天,对照组应用热奄包连续热敷5天,比较两组患者机械性静脉炎的发生率,穿刺手臂出血、肿胀及疼痛的情况。结果:机械性静脉炎发生率观察组[2.08%(1/48)]与对照组[0.00%(0/50)]比较,差异无统计学意义(P>0.05)。两组手臂疼痛程度、肿胀程度比较,差异无统计学差异(P>0.05)。观察组较对照组穿刺处出血少(P<0.05)。结论:PICC术后应用中药热奄包热敷3天即能有效预防机械性静脉炎,并可减轻穿刺引起的手臂疼痛、肿胀等早期不适症状,减少术后出血的风险。
