The isothermal solubility and physico-chemical properties(density,refractive index)of ternary system RbCl-EtOH-H 2 O at 25℃and 50℃have been firstly inve stigated by means of self-made micro-equilibrium and sampling ...The isothermal solubility and physico-chemical properties(density,refractive index)of ternary system RbCl-EtOH-H 2 O at 25℃and 50℃have been firstly inve stigated by means of self-made micro-equilibrium and sampling apparatus .The compositio ns of liquid and solid at equilibrium state were determined,and the probl em of analysis of ethanol content in syste m was properly solved.The phase diag ram was drawn by the TPD phase-diagra m computer program developed by us.Three empirical formulae were propose d to correlate the solubility,density and refractive index respectively.No d emixing phenomena was observed in th e range of temperature related in thi s study.展开更多
目的:探讨游离和总前列腺特异性抗原比值(f/tPSA)、外周血中性粒细胞和淋巴细胞比值(NLR)、白细胞介素6(IL-6)、前列腺健康指数密度(PHID)检测在前列腺癌早期诊断中的临床应用。方法:回顾性分析2020年1月至2022年1月徐州医科大学第二附...目的:探讨游离和总前列腺特异性抗原比值(f/tPSA)、外周血中性粒细胞和淋巴细胞比值(NLR)、白细胞介素6(IL-6)、前列腺健康指数密度(PHID)检测在前列腺癌早期诊断中的临床应用。方法:回顾性分析2020年1月至2022年1月徐州医科大学第二附属医院收治住院的160例前列腺特异性抗原(PSA)异常患者临床资料,根据前列腺穿刺活组织检查或电切手术病理结果分为前列腺癌组68例、良性前列腺增生组92例;选取同期徐州医科大学第二附属医院男性健康体检者50名为健康对照组。3组均检测总前列腺特异性抗原(tPSA)、游离前列腺特异性抗原(fPSA)、前列腺特异性抗原同源异构体2(p2PSA)、IL-6等指标,计算f/tPSA、前列腺健康指数(PHI)、PHID和NLR等。绘制受试者工作特征曲线(ROC),比较各指标诊断和鉴别诊断前列腺癌、良性前列腺增生的效能。结果:前列腺癌组患者血清tPSA、fPSA、p2PSA、PHI、PHID水平均高于良性前列腺增生组和健康对照组(均 P<0.05);血清f/tPSA水平均低于良性前列腺增生组和健康对照组(均 P<0.05)。PHID诊断早期前列腺癌的曲线下面积(AUC)最大[0.915(95% CI 0.864~0.966)],其次为PHI[0.884(95% CI 0.823~0.944)];f/tPSA和PHI诊断早期前列腺癌的灵敏度均为86.80%,高于其他指标;PHID诊断早期前列腺癌的特异度为94.00%,高于其他指标。f/tPSA诊断良性前列腺增生的AUC最大[0.828(95% CI 0.739~0.917)],其次为PHID[0.826(95% CI 0.760~0.892)];f/tPSA诊断良性前列腺增生的灵敏度高于其他指标,为85.90%;PHI诊断良性前列腺增生的特异度高于其他指标,为94.00%。fPSA、PHID、f/tPSA、p2PSA鉴别早期前列腺癌和良性前列腺增生的AUC分别为0.752(95% CI 0.663~0.841)、0.730(95% CI 0.647~0.812)、0.713(95% CI 0.623~0.803)、0.710(95% CI 0.629~0.791),各指标两两比较差异均无统计学意义(均 P>0.05)。NLR鉴别早期前列腺癌和良性前列腺增生的灵敏度均高于其他指标,�展开更多
Dynamic nonlinearities of C70/toluene solution are measured and analysed by an improved picosecond timeresolved pump-probe system based on a nonlinear imaging technique with phase object. The photophysical parameters ...Dynamic nonlinearities of C70/toluene solution are measured and analysed by an improved picosecond timeresolved pump-probe system based on a nonlinear imaging technique with phase object. The photophysical parameters are determined by the five-level model, which is adopted to interpret the experimental data. The change of refraction index per unit density of the excited state obtained by a numerically simulation is a critical factor to determine the nonlinear behaviour of C70 in picosecond time regime.展开更多
文摘The isothermal solubility and physico-chemical properties(density,refractive index)of ternary system RbCl-EtOH-H 2 O at 25℃and 50℃have been firstly inve stigated by means of self-made micro-equilibrium and sampling apparatus .The compositio ns of liquid and solid at equilibrium state were determined,and the probl em of analysis of ethanol content in syste m was properly solved.The phase diag ram was drawn by the TPD phase-diagra m computer program developed by us.Three empirical formulae were propose d to correlate the solubility,density and refractive index respectively.No d emixing phenomena was observed in th e range of temperature related in thi s study.
文摘目的:探讨游离和总前列腺特异性抗原比值(f/tPSA)、外周血中性粒细胞和淋巴细胞比值(NLR)、白细胞介素6(IL-6)、前列腺健康指数密度(PHID)检测在前列腺癌早期诊断中的临床应用。方法:回顾性分析2020年1月至2022年1月徐州医科大学第二附属医院收治住院的160例前列腺特异性抗原(PSA)异常患者临床资料,根据前列腺穿刺活组织检查或电切手术病理结果分为前列腺癌组68例、良性前列腺增生组92例;选取同期徐州医科大学第二附属医院男性健康体检者50名为健康对照组。3组均检测总前列腺特异性抗原(tPSA)、游离前列腺特异性抗原(fPSA)、前列腺特异性抗原同源异构体2(p2PSA)、IL-6等指标,计算f/tPSA、前列腺健康指数(PHI)、PHID和NLR等。绘制受试者工作特征曲线(ROC),比较各指标诊断和鉴别诊断前列腺癌、良性前列腺增生的效能。结果:前列腺癌组患者血清tPSA、fPSA、p2PSA、PHI、PHID水平均高于良性前列腺增生组和健康对照组(均 P<0.05);血清f/tPSA水平均低于良性前列腺增生组和健康对照组(均 P<0.05)。PHID诊断早期前列腺癌的曲线下面积(AUC)最大[0.915(95% CI 0.864~0.966)],其次为PHI[0.884(95% CI 0.823~0.944)];f/tPSA和PHI诊断早期前列腺癌的灵敏度均为86.80%,高于其他指标;PHID诊断早期前列腺癌的特异度为94.00%,高于其他指标。f/tPSA诊断良性前列腺增生的AUC最大[0.828(95% CI 0.739~0.917)],其次为PHID[0.826(95% CI 0.760~0.892)];f/tPSA诊断良性前列腺增生的灵敏度高于其他指标,为85.90%;PHI诊断良性前列腺增生的特异度高于其他指标,为94.00%。fPSA、PHID、f/tPSA、p2PSA鉴别早期前列腺癌和良性前列腺增生的AUC分别为0.752(95% CI 0.663~0.841)、0.730(95% CI 0.647~0.812)、0.713(95% CI 0.623~0.803)、0.710(95% CI 0.629~0.791),各指标两两比较差异均无统计学意义(均 P>0.05)。NLR鉴别早期前列腺癌和良性前列腺增生的灵敏度均高于其他指标,�
基金Project supported by the National Natural Science Fundation of China(Grant No.90922007)
文摘Dynamic nonlinearities of C70/toluene solution are measured and analysed by an improved picosecond timeresolved pump-probe system based on a nonlinear imaging technique with phase object. The photophysical parameters are determined by the five-level model, which is adopted to interpret the experimental data. The change of refraction index per unit density of the excited state obtained by a numerically simulation is a critical factor to determine the nonlinear behaviour of C70 in picosecond time regime.
