茅膏菜系茅膏菜科（Droseraceae）植物茅膏菜（Drosera pellata Smith Lunata（Buch-Ham.）C. B. Clarke）以全草人药。民间常用于祛风除湿,治疗跌打损伤及结核病。又为一常用藏药,在西藏地区民间用于治疗月经不调、瘰疠等症,又作为滋...茅膏菜系茅膏菜科（Droseraceae）植物茅膏菜（Drosera pellata Smith Lunata（Buch-Ham.）C. B. Clarke）以全草人药。民间常用于祛风除湿,治疗跌打损伤及结核病。又为一常用藏药,在西藏地区民间用于治疗月经不调、瘰疠等症,又作为滋补药。文献报道含有萘醌成分。 样品采于西藏。全草干燥细粉重5.5kg,用乙醇提取,粗提物的乙醚溶解部分经反复硅胶柱层析,得到一种新的茚满酮,命名为:泊尔酮A（peltatone A）（Ⅰ）50 mg;0.00091％。 根据元素分析和质谱数据,相应分子式为C10H8O5,Ω=7,IR提示含有苯环、羟基及羰基,三氯化铁-铁氰化钾显蓝色。1H NMR提示存在2个芳氢（δ7.38,s）,1个甲基（δ1.70,s）,乙酰化物1H NMR提示Ⅰ含有2个酚羟基,1个醇羟基。IR说明有β—双酮结构(VmaxKBr cm-1:1730,1693),13C NMR及DEPT谱也说明分广内存在对称结构,确定Ⅰ的结构为2—甲基,2,4,7—三羟基—1,3—茚二酮。展开更多
The syntheses of three novel substituted indanones namely 2,7 dimethylindan 1 one, 2 methyl 4,7 diethylindan 1 one and 2,4 dimethyl 7 methoxyindan 1 one are described. These indanones were prepared by different routes...The syntheses of three novel substituted indanones namely 2,7 dimethylindan 1 one, 2 methyl 4,7 diethylindan 1 one and 2,4 dimethyl 7 methoxyindan 1 one are described. These indanones were prepared by different routes involving intramolecular ring closure of aryl substituted compounds by Friedel Crafts reaction. The t butyl was used as the positional protective group in the selective preparation of 2,7 dimethylindan 1 one. The corresponding indenes were prepared by reduction and dehydration reactions from these indanones.展开更多
文摘The syntheses of three novel substituted indanones namely 2,7 dimethylindan 1 one, 2 methyl 4,7 diethylindan 1 one and 2,4 dimethyl 7 methoxyindan 1 one are described. These indanones were prepared by different routes involving intramolecular ring closure of aryl substituted compounds by Friedel Crafts reaction. The t butyl was used as the positional protective group in the selective preparation of 2,7 dimethylindan 1 one. The corresponding indenes were prepared by reduction and dehydration reactions from these indanones.
