目的分析1990-2019年我国肌肉骨骼疾病负担变化情况。方法基于全球健康数据交换库(Global Health Data Exchange,GHDx),利用发病率、患病率和伤残调整寿命年(disability adjusted life year,DALY)等指标评价类风湿性关节炎、骨关节炎、...目的分析1990-2019年我国肌肉骨骼疾病负担变化情况。方法基于全球健康数据交换库(Global Health Data Exchange,GHDx),利用发病率、患病率和伤残调整寿命年(disability adjusted life year,DALY)等指标评价类风湿性关节炎、骨关节炎、腰痛、颈痛和痛风等肌肉骨骼疾病负担,利用Joinpoint回归模型计算平均年度变化百分比(average annual percentage change,AAPC),分析肌肉骨骼疾病负担变化趋势。结果2019年我国肌肉骨骼疾病标化发病率和DALY率分别为3764.99/10万和1585.44/10万,较1990年分别下降17.80%和6.05%。除痛风外,女性各类肌肉骨骼疾病的标化发病率和DALY率均高于男性。1990-2019年肌肉骨骼疾病标化发病率和DALY率总体呈下降趋势,AAPC分别为-0.68%和-0.22%,其中腰痛下降最明显而痛风呈较明显的上升趋势。骨关节炎、腰痛和痛风可归因于高BMI的疾病负担持续增加,腰痛可归因于吸烟和职业工效学因素的疾病负担下降,痛风可归因于肾功能损伤的疾病负担上升。结论1990-2019年我国肌肉骨骼疾病负担总体呈下降趋势,主要是由于腰痛的疾病负担明显下降,类风湿性关节炎、骨关节炎、颈痛和痛风等疾病的防控形势依然严峻。展开更多
Objective: The purpose of this study was to evaluate the true incidence and the risk factors associated with carotid disease in the sitting of high risk patients undergoing coronary artery bypass graft (CABG) using ca...Objective: The purpose of this study was to evaluate the true incidence and the risk factors associated with carotid disease in the sitting of high risk patients undergoing coronary artery bypass graft (CABG) using carotid duplex scan and to find out if routine preoperative carotid duplex scan is needed among all these patients. Methods: This retrospective study included 402 consecutive patients who underwent bilateral carotid duplex scan admitted for CABG during the period from January 2006 to December 2008. We excluded patients in cardiogenic shock who were taken to operating room emergently. Results: The prevalence of associated risk factors showed diabetes mellitus recorded the highest (93.3%) whereas peripheral vascular disease the lowest (1.7%), hypertension (89.3%), dyslipidemia (72.6%), smoker (21.1%), left main disease (4.7%), and previous stroke (3%). Patients undergoing CABG has high incidence of carotid disease (68.7%) and severe stenosis is more in patients aged 60 and above (13.5%) versus (2.3%) in age 60, previous stroke and left main disease). Conclusion: This study showed that carotid screening is recommended for all patients who are undergoing CABG due to high incidence of carotid disease.展开更多
To search factors influencing morbidity between coronary heart disease(CHD) and stroke, a longitudinal prospective study was done in a cohort of 1 809 participants aged 3574 at entry of Jiangsu province, China. The av...To search factors influencing morbidity between coronary heart disease(CHD) and stroke, a longitudinal prospective study was done in a cohort of 1 809 participants aged 3574 at entry of Jiangsu province, China. The average annual agedadjusted incidence of stroke was 142.3/\{100 000\}, being over 1315 years more than that of coronary event(CE)(49.1/100 000), the difference of the incidences between the two diseases was very significant(P<0.01). Multivariate regression analysis revealed that the main risk factors of CHD include increase of serum total cholecsterol, hypertension and mental stress, whereas the most important risk factors for stroke consist of elevation of systolic blood pressure(SBP) as well as smoking and alcohol drinking habit. It was noted that these participants in cohort usually had high salt intake, low animal protein diet, and low level of serum cholecsterol with high level of blood presure and smoking and alcohol habit. We suggest that rational dietary food, stopping smoking, limited alcohol and community control of hypertension are the preventive strategy against these diseases.展开更多
文摘目的分析1990-2019年我国肌肉骨骼疾病负担变化情况。方法基于全球健康数据交换库(Global Health Data Exchange,GHDx),利用发病率、患病率和伤残调整寿命年(disability adjusted life year,DALY)等指标评价类风湿性关节炎、骨关节炎、腰痛、颈痛和痛风等肌肉骨骼疾病负担,利用Joinpoint回归模型计算平均年度变化百分比(average annual percentage change,AAPC),分析肌肉骨骼疾病负担变化趋势。结果2019年我国肌肉骨骼疾病标化发病率和DALY率分别为3764.99/10万和1585.44/10万,较1990年分别下降17.80%和6.05%。除痛风外,女性各类肌肉骨骼疾病的标化发病率和DALY率均高于男性。1990-2019年肌肉骨骼疾病标化发病率和DALY率总体呈下降趋势,AAPC分别为-0.68%和-0.22%,其中腰痛下降最明显而痛风呈较明显的上升趋势。骨关节炎、腰痛和痛风可归因于高BMI的疾病负担持续增加,腰痛可归因于吸烟和职业工效学因素的疾病负担下降,痛风可归因于肾功能损伤的疾病负担上升。结论1990-2019年我国肌肉骨骼疾病负担总体呈下降趋势,主要是由于腰痛的疾病负担明显下降,类风湿性关节炎、骨关节炎、颈痛和痛风等疾病的防控形势依然严峻。
文摘Objective: The purpose of this study was to evaluate the true incidence and the risk factors associated with carotid disease in the sitting of high risk patients undergoing coronary artery bypass graft (CABG) using carotid duplex scan and to find out if routine preoperative carotid duplex scan is needed among all these patients. Methods: This retrospective study included 402 consecutive patients who underwent bilateral carotid duplex scan admitted for CABG during the period from January 2006 to December 2008. We excluded patients in cardiogenic shock who were taken to operating room emergently. Results: The prevalence of associated risk factors showed diabetes mellitus recorded the highest (93.3%) whereas peripheral vascular disease the lowest (1.7%), hypertension (89.3%), dyslipidemia (72.6%), smoker (21.1%), left main disease (4.7%), and previous stroke (3%). Patients undergoing CABG has high incidence of carotid disease (68.7%) and severe stenosis is more in patients aged 60 and above (13.5%) versus (2.3%) in age 60, previous stroke and left main disease). Conclusion: This study showed that carotid screening is recommended for all patients who are undergoing CABG due to high incidence of carotid disease.
文摘To search factors influencing morbidity between coronary heart disease(CHD) and stroke, a longitudinal prospective study was done in a cohort of 1 809 participants aged 3574 at entry of Jiangsu province, China. The average annual agedadjusted incidence of stroke was 142.3/\{100 000\}, being over 1315 years more than that of coronary event(CE)(49.1/100 000), the difference of the incidences between the two diseases was very significant(P<0.01). Multivariate regression analysis revealed that the main risk factors of CHD include increase of serum total cholecsterol, hypertension and mental stress, whereas the most important risk factors for stroke consist of elevation of systolic blood pressure(SBP) as well as smoking and alcohol drinking habit. It was noted that these participants in cohort usually had high salt intake, low animal protein diet, and low level of serum cholecsterol with high level of blood presure and smoking and alcohol habit. We suggest that rational dietary food, stopping smoking, limited alcohol and community control of hypertension are the preventive strategy against these diseases.