目的探讨成人癫痫患者疾病感知的特点及其对生活质量的影响。方法采用横断面研究,对98例成人癫痫患者和同期就诊的75例糖尿病患者,使用疾病感知问卷中文修订版(Chinese illness perception questionnaire revised edition,CIPQ-R)进行评...目的探讨成人癫痫患者疾病感知的特点及其对生活质量的影响。方法采用横断面研究,对98例成人癫痫患者和同期就诊的75例糖尿病患者,使用疾病感知问卷中文修订版(Chinese illness perception questionnaire revised edition,CIPQ-R)进行评估,比较两组间疾病感知各因子的差异;采用癫痫患者生活质量量表(quality of life in epilepsy-31,QOLIE-31)对98例成人癫痫患者及55名健康人进行生活质量的评估,并应用相关和多元回归分析探讨疾病感知各因子对成人癫痫患者生活质量的影响。结果(1)癫痫组CIPQ-R中的情绪陈述因子得分[(21.73±5.79)分]高于糖尿病组得分[(18.76±5.42)分],差异有统计学意义(P<0.01);癫痫组CIPQ-R中的疾病急/慢性、个人控制性、疾病相关性三个因子得分[(16.47±4.68)分、(20.91±4.03)分、(15.21±4.44)分]均低于糖尿病组得分[(19.16±4.75)分、(22.68±3.90)分、(16.56±3.73)分],差异有统计学意义(P<0.05);癫痫患者生活质量量表多个因子得分均低于健康对照组,差异有统计学意义(t=-2.264^-8.203,P<0.01)。(2)相关分析显示:癫痫组CIPQ-R中的情绪陈述、严重后果因子与QOLIE-31的总分及其所属的各因子均呈显著负相关(r=-0.202^-0.527,P<0.05);癫痫组CIPQ-R中的疾病同一性、疾病急/慢性、疾病周期性因子与QOLIE-31的总分呈负相关(r=-0.272^-0.342,P<0.01);癫痫组CIPQ-R中的治疗控制性、疾病相关性因子与QOLIE-31的总分呈正相关(r=0.259,r=0.307,均P<0.01)。(3)多元逐步线性回归显示,疾病感知之疾病同一性、疾病急/慢性、严重后果、疾病周期性、情绪陈述因子是成人癫痫患者生活质量的重要影响因素。结论成人癫痫患者具有负性疾病感知,其中疾病感知的疾病同一性、疾病急/慢性、严重后果、疾病周期性、情绪陈述因子对成人癫痫患者生活质量具有显著影响。展开更多
AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis.METHODS One hundred adults with decompensated cirrhosis compl...AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis.METHODS One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky Medication Adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic Liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. Least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = 0.05.RESULTS Medication adherence was " High " in 42 % o f participants, "Medium" in 37%, and "Low" in 21%. Compared to patients with "High" adherence, those with "Medium" or "Low" adherence were more likely to report difficulty affording their medications(P < 0.001), lower perception of treatment helpfulness(P = 0.003) and stronger medication concerns relative to medication necessity beliefs(P = 0.003). People with "Low" adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of "Low"adherence.CONCLUSION The association between "Low" adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explored further given the clinical relevance.展开更多
Introduction: Lower health-related quality of life (HRQoL) is associated with fatigue, poor mental and poor gastrointestinal health during the first three months after colorectal cancer (CRC) treatment. Research indic...Introduction: Lower health-related quality of life (HRQoL) is associated with fatigue, poor mental and poor gastrointestinal health during the first three months after colorectal cancer (CRC) treatment. Research indicates that maintaining usual activities has a positive impact on HRQoL after treatment for CRC. Illness perceptions have been associated with HRQoL in other cancer diseases, and self-efficacy has been associated with HRQoL in gastrointestinal cancer survivors. Our knowledge about illness perceptions and self-efficacy in relation to maintaining everyday activities and HRQoL following CRC treatment is incomplete. Aim: To explore associations between HRQoL, fatigue, mental health, gastrointestinal health, illness perceptions and self-efficacy in relation to maintaining everyday activities, three months after surgical CRC treatment. A further aim was to test the Maintain Function Scale in a CRC population. Method: The study was cross-sectional. Forty-six persons participated. Data were collected using questionnaires. Descriptive and analytical statistics were used. Results: Persons who were more fatigued, depressed, worried, and had more diarrhea were more likely to report lower HRQoL. Increased fatigue and diarrhea were associated with decreased HRQoL. Concerning illness perceptions, persons who reported negative emotions and negative consequences of CRC were more likely to report lower HRQoL. Persons scoring higher on self-efficacy were more likely to report higher HRQoL. Increased self-efficacy was associated with increased HRQoL. The Maintain Function Scale was suitable for assessing self-efficacy in relation to maintaining everyday activities. Conclusions: Nursing support to improve self-efficacy and illness perceptions and to minimize symptoms during recovery should have a favorable impact on HRQoL.展开更多
文摘目的探讨成人癫痫患者疾病感知的特点及其对生活质量的影响。方法采用横断面研究,对98例成人癫痫患者和同期就诊的75例糖尿病患者,使用疾病感知问卷中文修订版(Chinese illness perception questionnaire revised edition,CIPQ-R)进行评估,比较两组间疾病感知各因子的差异;采用癫痫患者生活质量量表(quality of life in epilepsy-31,QOLIE-31)对98例成人癫痫患者及55名健康人进行生活质量的评估,并应用相关和多元回归分析探讨疾病感知各因子对成人癫痫患者生活质量的影响。结果(1)癫痫组CIPQ-R中的情绪陈述因子得分[(21.73±5.79)分]高于糖尿病组得分[(18.76±5.42)分],差异有统计学意义(P<0.01);癫痫组CIPQ-R中的疾病急/慢性、个人控制性、疾病相关性三个因子得分[(16.47±4.68)分、(20.91±4.03)分、(15.21±4.44)分]均低于糖尿病组得分[(19.16±4.75)分、(22.68±3.90)分、(16.56±3.73)分],差异有统计学意义(P<0.05);癫痫患者生活质量量表多个因子得分均低于健康对照组,差异有统计学意义(t=-2.264^-8.203,P<0.01)。(2)相关分析显示:癫痫组CIPQ-R中的情绪陈述、严重后果因子与QOLIE-31的总分及其所属的各因子均呈显著负相关(r=-0.202^-0.527,P<0.05);癫痫组CIPQ-R中的疾病同一性、疾病急/慢性、疾病周期性因子与QOLIE-31的总分呈负相关(r=-0.272^-0.342,P<0.01);癫痫组CIPQ-R中的治疗控制性、疾病相关性因子与QOLIE-31的总分呈正相关(r=0.259,r=0.307,均P<0.01)。(3)多元逐步线性回归显示,疾病感知之疾病同一性、疾病急/慢性、严重后果、疾病周期性、情绪陈述因子是成人癫痫患者生活质量的重要影响因素。结论成人癫痫患者具有负性疾病感知,其中疾病感知的疾病同一性、疾病急/慢性、严重后果、疾病周期性、情绪陈述因子对成人癫痫患者生活质量具有显著影响。
文摘AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis.METHODS One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky Medication Adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic Liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. Least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = 0.05.RESULTS Medication adherence was " High " in 42 % o f participants, "Medium" in 37%, and "Low" in 21%. Compared to patients with "High" adherence, those with "Medium" or "Low" adherence were more likely to report difficulty affording their medications(P < 0.001), lower perception of treatment helpfulness(P = 0.003) and stronger medication concerns relative to medication necessity beliefs(P = 0.003). People with "Low" adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of "Low"adherence.CONCLUSION The association between "Low" adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explored further given the clinical relevance.
文摘Introduction: Lower health-related quality of life (HRQoL) is associated with fatigue, poor mental and poor gastrointestinal health during the first three months after colorectal cancer (CRC) treatment. Research indicates that maintaining usual activities has a positive impact on HRQoL after treatment for CRC. Illness perceptions have been associated with HRQoL in other cancer diseases, and self-efficacy has been associated with HRQoL in gastrointestinal cancer survivors. Our knowledge about illness perceptions and self-efficacy in relation to maintaining everyday activities and HRQoL following CRC treatment is incomplete. Aim: To explore associations between HRQoL, fatigue, mental health, gastrointestinal health, illness perceptions and self-efficacy in relation to maintaining everyday activities, three months after surgical CRC treatment. A further aim was to test the Maintain Function Scale in a CRC population. Method: The study was cross-sectional. Forty-six persons participated. Data were collected using questionnaires. Descriptive and analytical statistics were used. Results: Persons who were more fatigued, depressed, worried, and had more diarrhea were more likely to report lower HRQoL. Increased fatigue and diarrhea were associated with decreased HRQoL. Concerning illness perceptions, persons who reported negative emotions and negative consequences of CRC were more likely to report lower HRQoL. Persons scoring higher on self-efficacy were more likely to report higher HRQoL. Increased self-efficacy was associated with increased HRQoL. The Maintain Function Scale was suitable for assessing self-efficacy in relation to maintaining everyday activities. Conclusions: Nursing support to improve self-efficacy and illness perceptions and to minimize symptoms during recovery should have a favorable impact on HRQoL.
