Objective To explore the therapeutic efficacy and mechanism of acupuncture at Lieque (列缺 LU 7) in treatment of cervical vertigo (CV). Methods Forty CV patients met the inclusion criteria were enrolled and treate...Objective To explore the therapeutic efficacy and mechanism of acupuncture at Lieque (列缺 LU 7) in treatment of cervical vertigo (CV). Methods Forty CV patients met the inclusion criteria were enrolled and treated with acupuncture at bilateral LU 7 points, once daily with 10 times as a course. The changes of blood flow velocity in bilateral vertebral artery and basilar artery were observed through transcranial doppler sonography (TCD) before treatment, after deqi with acupuncture and after a course of treatment, respectively. The scores and therapeutic efficacy on clinical symptoms were assessed according to CV symptoms and the functional assessment scale as well as the Criteria-for Diagnosis and Curative Effect in TCM Syndromes before treatment and after a course of treatment. Results Before treatment, after deqi and after a course of treatment, the blood flow velocity of basilar artery (BA), left vertebral artery (LVA) and right vertebral artery (RVA) in 22 patients with a decreased blood flow velocity were respectively 23.20±4.84 vs 26.30 ± 4.17 vs 29.20 ± 4.20 (mm/s, BA), 21.65 ± 3.62 vs 24.20 ± 2.89 vs 26.40 ± 3.62 (mm/s, LVA) and 21.90±3.04 vs 24.25±3.01 vs 26.50_±3.95 (mm/s, RVA), while in 18 patients with an increased blood flow velocity were respectively 39.94 ± 8.24 vs 35.17 ± 4.84 vs 32.06 ± 3.49 (mm/s, BA), 41.83 ± 5.64 vs 37.28 ± 2.32 vs 35.61 ± 2.09 (mm/s, LVA) and 37.11 ± 9.83 vs 32.22 ± 6.13 vs 28.11 ± 4.12 (mm/s, RVA). Except that the difference of blood flow velocity of RVA was not significant in patients with an increased blood flow velocity before treatment and after deqi (P 〉 0.05), the Vm of all vessels in 40 patients was improved after deqi with acupuncture and a course of treatment (P〈0.01, P〈0.05). According to CV symptoms and the functional assessment scale, before treatment and after a course of treatment, the scores were 15.68 ± 5.35 and 26.30 ± 3.76, respectively, indicating that after a course of tre展开更多
Graphene quantum dots(GQDs)doped InGaO(IGO)thin film transistors(TFTs)have been fabricated based on solution-driven ZrO_(x) as gate dielectrics.Compare to pure IGO TFTs,superior electrical performance of the GQDs-IGO ...Graphene quantum dots(GQDs)doped InGaO(IGO)thin film transistors(TFTs)have been fabricated based on solution-driven ZrO_(x) as gate dielectrics.Compare to pure IGO TFTs,superior electrical performance of the GQDs-IGO TFTs can be achieved by adjusting the doping concentration.It has been demonstrated that GQDs-modified IGO TFTs devices with GQDs doping content of0.3 mg·ml^(-1)have the optimized performances,including field-effect mobility(μ_(FE))of 22.02 cm^(2)·V^(-1)·s^(-1),on/off current ratio(I_(on)/I_(off))of 7.06×10^(7),subthreshold swing(SS)of 0.09 V·dec^(-1),hysteresis of 0.04 V and interfacial trap states(D_(it))of 1.03×10^(12)cm^(-2).In addition,bias stress and illumination stress tests have been performed and excellent stability has been achieved for optimized GQDs-IGO-TFTs.The GQDs-IGO TFTs device showed smaller threshold voltage shift of 0.12 and 0.04 V under positive bias stress(PBS)test and negative bias stress(NBS)test for 3600 s,respectively.And it showed smaller threshold voltage shift of 0.27 and 0.34 V for red light under the PBS and NBS test for 3600 s,respectively.Meanwhile,it showed smaller threshold voltage shift of0.20 and 0.22 V for green light under PBS and NBS test for3600 s,respectively.It also showed smaller threshold voltage shift of 0.17 and 0.12 V for blue under the positive bias illumination stress(PBIS)test and negative bias illumination stress(NBIS)test for 3600 s,respectively.Lowfrequency noise(LFN)characteristics of GQDs-IGO/ZrO_(x)TFTs indicated that the noise source came from the fluctuations in mobility.Finally,a low voltage resistor-loaded unipolar inverter has been built based on GQDs-IGO/ZrO_(x)TFT,demonstrating good dynamic response behavior and a maximum gain of 7.4.These experimental results have suggested that solution-processed GQDs-IGO/ZrO_(x)TFT may envision potential applications in low-cost and large-area electronics.展开更多
The optimum reaction conditions of the oxidative polycondensation of 2-(thien-2-yl-methylene)aminophenol (2-TMAP) has been accomplished by using air O_2,H_2O_2 and NaOCl oxidants in an aqueous alkaline medium between...The optimum reaction conditions of the oxidative polycondensation of 2-(thien-2-yl-methylene)aminophenol (2-TMAP) has been accomplished by using air O_2,H_2O_2 and NaOCl oxidants in an aqueous alkaline medium between 20℃and 90℃.The structures of the monomer and oligomer were confirmed by FT-IR,UV-Vis,~1H-NMR and ^(13)C-NMR and elemental analysis.TGA-DTA,size exclusion chromatography(SEC) techniques and solubility tests were applied for characterization.The ~1H-NMR and ^(13)C-NMR data show that the polymeriz...展开更多
文摘Objective To explore the therapeutic efficacy and mechanism of acupuncture at Lieque (列缺 LU 7) in treatment of cervical vertigo (CV). Methods Forty CV patients met the inclusion criteria were enrolled and treated with acupuncture at bilateral LU 7 points, once daily with 10 times as a course. The changes of blood flow velocity in bilateral vertebral artery and basilar artery were observed through transcranial doppler sonography (TCD) before treatment, after deqi with acupuncture and after a course of treatment, respectively. The scores and therapeutic efficacy on clinical symptoms were assessed according to CV symptoms and the functional assessment scale as well as the Criteria-for Diagnosis and Curative Effect in TCM Syndromes before treatment and after a course of treatment. Results Before treatment, after deqi and after a course of treatment, the blood flow velocity of basilar artery (BA), left vertebral artery (LVA) and right vertebral artery (RVA) in 22 patients with a decreased blood flow velocity were respectively 23.20±4.84 vs 26.30 ± 4.17 vs 29.20 ± 4.20 (mm/s, BA), 21.65 ± 3.62 vs 24.20 ± 2.89 vs 26.40 ± 3.62 (mm/s, LVA) and 21.90±3.04 vs 24.25±3.01 vs 26.50_±3.95 (mm/s, RVA), while in 18 patients with an increased blood flow velocity were respectively 39.94 ± 8.24 vs 35.17 ± 4.84 vs 32.06 ± 3.49 (mm/s, BA), 41.83 ± 5.64 vs 37.28 ± 2.32 vs 35.61 ± 2.09 (mm/s, LVA) and 37.11 ± 9.83 vs 32.22 ± 6.13 vs 28.11 ± 4.12 (mm/s, RVA). Except that the difference of blood flow velocity of RVA was not significant in patients with an increased blood flow velocity before treatment and after deqi (P 〉 0.05), the Vm of all vessels in 40 patients was improved after deqi with acupuncture and a course of treatment (P〈0.01, P〈0.05). According to CV symptoms and the functional assessment scale, before treatment and after a course of treatment, the scores were 15.68 ± 5.35 and 26.30 ± 3.76, respectively, indicating that after a course of tre
基金financially supported by the National Natural Science Foundation of China(No.11774001)Anhui Project(No.Z010118169)Open Fund Project of Zhejiang Engineering Research Center of MEMS in Shaoxing University(No.MEMSZJERC2202)。
文摘Graphene quantum dots(GQDs)doped InGaO(IGO)thin film transistors(TFTs)have been fabricated based on solution-driven ZrO_(x) as gate dielectrics.Compare to pure IGO TFTs,superior electrical performance of the GQDs-IGO TFTs can be achieved by adjusting the doping concentration.It has been demonstrated that GQDs-modified IGO TFTs devices with GQDs doping content of0.3 mg·ml^(-1)have the optimized performances,including field-effect mobility(μ_(FE))of 22.02 cm^(2)·V^(-1)·s^(-1),on/off current ratio(I_(on)/I_(off))of 7.06×10^(7),subthreshold swing(SS)of 0.09 V·dec^(-1),hysteresis of 0.04 V and interfacial trap states(D_(it))of 1.03×10^(12)cm^(-2).In addition,bias stress and illumination stress tests have been performed and excellent stability has been achieved for optimized GQDs-IGO-TFTs.The GQDs-IGO TFTs device showed smaller threshold voltage shift of 0.12 and 0.04 V under positive bias stress(PBS)test and negative bias stress(NBS)test for 3600 s,respectively.And it showed smaller threshold voltage shift of 0.27 and 0.34 V for red light under the PBS and NBS test for 3600 s,respectively.Meanwhile,it showed smaller threshold voltage shift of0.20 and 0.22 V for green light under PBS and NBS test for3600 s,respectively.It also showed smaller threshold voltage shift of 0.17 and 0.12 V for blue under the positive bias illumination stress(PBIS)test and negative bias illumination stress(NBIS)test for 3600 s,respectively.Lowfrequency noise(LFN)characteristics of GQDs-IGO/ZrO_(x)TFTs indicated that the noise source came from the fluctuations in mobility.Finally,a low voltage resistor-loaded unipolar inverter has been built based on GQDs-IGO/ZrO_(x)TFT,demonstrating good dynamic response behavior and a maximum gain of 7.4.These experimental results have suggested that solution-processed GQDs-IGO/ZrO_(x)TFT may envision potential applications in low-cost and large-area electronics.
基金supported by the Government Planning Organization(GPO2002K120170-7)TUBITAK GrantsCommission for a research grant(No.TBAG-105T428).
文摘The optimum reaction conditions of the oxidative polycondensation of 2-(thien-2-yl-methylene)aminophenol (2-TMAP) has been accomplished by using air O_2,H_2O_2 and NaOCl oxidants in an aqueous alkaline medium between 20℃and 90℃.The structures of the monomer and oligomer were confirmed by FT-IR,UV-Vis,~1H-NMR and ^(13)C-NMR and elemental analysis.TGA-DTA,size exclusion chromatography(SEC) techniques and solubility tests were applied for characterization.The ~1H-NMR and ^(13)C-NMR data show that the polymeriz...
基金National Natural Science Foundation of China(31300483)Natural Science Foundation of Jiangsu Province,China(BK20130971)+1 种基金Northern Jiangsu Science and Technology Development Program of Jiangsu Province,China(BC2013432)College Student Innovation Training Program of Nanjing Forestry University in 2015~~