目的:探讨围绝经期前后妇女潮热与焦虑、抑郁之间的关系。方法:将符合条件的1 206名40~60岁妇女分为潮热组、无潮热组,分别完成调查问卷。问卷具体内容包括一般情况、潮热状况、焦虑自评量表(SAS)、抑郁自评量表(SDS)。结果:潮...目的:探讨围绝经期前后妇女潮热与焦虑、抑郁之间的关系。方法:将符合条件的1 206名40~60岁妇女分为潮热组、无潮热组,分别完成调查问卷。问卷具体内容包括一般情况、潮热状况、焦虑自评量表(SAS)、抑郁自评量表(SDS)。结果:潮热组妇女SAS和SDS的平均值高于无潮热组妇女(SAS:39.8±7.3 vs 36.0±6.1;SDS:44.1±8.3 vs 40.9±8.9,P均〈0.05),潮热组轻度焦虑和抑郁的发生率明显高于无潮热组(焦虑:8.3%vs 3.4%;抑郁:23.3%vs 14.2%,P均〈0.05)。潮热妇女焦虑、抑郁的发生风险分别是无潮热妇女的4.1倍(95%CI,1.20~13.74)、2.4倍(95%CI,1.15~4.92)。重度潮热妇女较轻度潮热妇女SAS和SDS得分均高(SAS:46.4±7.9 vs 38.8±6.6;SDS:43.9±6.9 vs 52.7±12.5,P均〈0.05)。潮热妇女的月经状况与SAS和SDS得分无关。结论:围绝经期潮热妇女易发生焦虑、抑郁症状,且重度潮热妇女更易发生。对妇女进行潮热治疗时,还应对妇女进行心理疏导。展开更多
Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. While efficacious, ADT is associated with multiple side effects, including d...Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. While efficacious, ADT is associated with multiple side effects, including decreased libido, erectile dysfunction, diabetes, loss of muscle tone and altered body composition, osteoporosis, lipid changes, memory loss, gynecomastia and hot flashes. The breadth of literature for the treatment of hot flashes is much smaller in men than that in women. While hormonal therapy of hot flashes has been shown to be effective, multiple non-hormonal medications and treatment methods have also been developed. This article reviews current options for the treatment of hot flashes in patients taking ADT.展开更多
文摘目的:探讨围绝经期前后妇女潮热与焦虑、抑郁之间的关系。方法:将符合条件的1 206名40~60岁妇女分为潮热组、无潮热组,分别完成调查问卷。问卷具体内容包括一般情况、潮热状况、焦虑自评量表(SAS)、抑郁自评量表(SDS)。结果:潮热组妇女SAS和SDS的平均值高于无潮热组妇女(SAS:39.8±7.3 vs 36.0±6.1;SDS:44.1±8.3 vs 40.9±8.9,P均〈0.05),潮热组轻度焦虑和抑郁的发生率明显高于无潮热组(焦虑:8.3%vs 3.4%;抑郁:23.3%vs 14.2%,P均〈0.05)。潮热妇女焦虑、抑郁的发生风险分别是无潮热妇女的4.1倍(95%CI,1.20~13.74)、2.4倍(95%CI,1.15~4.92)。重度潮热妇女较轻度潮热妇女SAS和SDS得分均高(SAS:46.4±7.9 vs 38.8±6.6;SDS:43.9±6.9 vs 52.7±12.5,P均〈0.05)。潮热妇女的月经状况与SAS和SDS得分无关。结论:围绝经期潮热妇女易发生焦虑、抑郁症状,且重度潮热妇女更易发生。对妇女进行潮热治疗时,还应对妇女进行心理疏导。
文摘Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. While efficacious, ADT is associated with multiple side effects, including decreased libido, erectile dysfunction, diabetes, loss of muscle tone and altered body composition, osteoporosis, lipid changes, memory loss, gynecomastia and hot flashes. The breadth of literature for the treatment of hot flashes is much smaller in men than that in women. While hormonal therapy of hot flashes has been shown to be effective, multiple non-hormonal medications and treatment methods have also been developed. This article reviews current options for the treatment of hot flashes in patients taking ADT.