Objective To investigate the reproductive and sexual health situation, including knowledge, attitudes, and behaviors, among a population-based sample of internal migrant workers in China. Methods A cross-sectional sur...Objective To investigate the reproductive and sexual health situation, including knowledge, attitudes, and behaviors, among a population-based sample of internal migrant workers in China. Methods A cross-sectional survey of 4 900 rural-to-urban migrants in 6 provinces of China was conducted. Participants completed a 30-min semi-structured questionnaire about contraceptive practices, sexual behavior, and HIV-related knowledge. Results Migrants lacked knowledge of reproductive and sexual health issues. Among those who had heard any sexually transmitted infections （STIs）, only 79.1%, 46.2%, 86.1%, 14.5% and 82.2%, respectively, knew that gonorrhea, condyloma, syphilis, chancroid, and AIDS were STIs. About three-quarters of participants had not used any contraceptive method at sexual debut. Among current users of contraceptive methods, 85.5% indicated that they were satisfied with the method. Before adoption of a contraceptive method, 46.6% of the migrant workers were unaware of the advantages/ disadvantages of the method and 75.3% had no knowledge of emergency contraception. Nearly one-quarter （23.4%） reported that they had premarital sex. Among migrants who were sexually active one month prior to the survey, only 14.0% reported that they had used condoms. Conclusion The limited sexual and reproductive health knowledge and unmet reproductive health services of migrant workers in China underscore the need for a comprehensive package of sexual and reproductive health interventions that combine cognitive and behavioral skills training and target both migrants and health care providers.展开更多
文摘Objective To investigate the reproductive and sexual health situation, including knowledge, attitudes, and behaviors, among a population-based sample of internal migrant workers in China. Methods A cross-sectional survey of 4 900 rural-to-urban migrants in 6 provinces of China was conducted. Participants completed a 30-min semi-structured questionnaire about contraceptive practices, sexual behavior, and HIV-related knowledge. Results Migrants lacked knowledge of reproductive and sexual health issues. Among those who had heard any sexually transmitted infections （STIs）, only 79.1%, 46.2%, 86.1%, 14.5% and 82.2%, respectively, knew that gonorrhea, condyloma, syphilis, chancroid, and AIDS were STIs. About three-quarters of participants had not used any contraceptive method at sexual debut. Among current users of contraceptive methods, 85.5% indicated that they were satisfied with the method. Before adoption of a contraceptive method, 46.6% of the migrant workers were unaware of the advantages/ disadvantages of the method and 75.3% had no knowledge of emergency contraception. Nearly one-quarter （23.4%） reported that they had premarital sex. Among migrants who were sexually active one month prior to the survey, only 14.0% reported that they had used condoms. Conclusion The limited sexual and reproductive health knowledge and unmet reproductive health services of migrant workers in China underscore the need for a comprehensive package of sexual and reproductive health interventions that combine cognitive and behavioral skills training and target both migrants and health care providers.
文摘目的探讨HIV-1感染者慢性期治疗前后CD8^＋Tscm（stem memory Tcell）的特点及其与疾病进展的相关性。方法选取36例HIV-1慢性期感染者和20名健康对照者。用流式细胞术检测健康对照者和HIV-1感染者抗病毒治疗前后CD8^＋Tscm的比例和数量。分析CD8^＋Tscm与其他CD8^＋T细胞亚群和疾病进展指标（CIM^＋T细胞数量、病毒载量和T细胞活化水平）的相关性。结果抗病毒治疗前后，HIV-1慢性期感染者CD8^＋Tscm的比例和数量均无显著性变化。HIV-1慢性期感染者CD8^＋Tscm的比例和数量均与CIM^＋Tscm的比例和数量呈正相关性。CD8^＋Tscm的比例与CD8^＋Tcm（central memory T cell）的比例成正比．与CD8^＋Tern（effector memory T cell）的比例成反比。此外，在抗病毒治疗前，HIV-1慢性期感染者CD8^＋Tscm的比例与病毒载量呈负相关。结论CD8^＋Tscm参与维持其他CD8^＋T细胞亚群的稳态：CD8^＋Tscm参与抑制病毒的复制。
