Most reinforced concrete structures in seaside locations suffer from corrosion damage to the reinforcement, limiting their durability and necessitating costly repairs. To improve their performance and durability, we h...Most reinforced concrete structures in seaside locations suffer from corrosion damage to the reinforcement, limiting their durability and necessitating costly repairs. To improve their performance and durability, we have investigated in this paper Aloe vera extracts as a green corrosion inhibitor for reinforcing steel in NaCl environments. Using electrochemical methods (zero-intensity chronopotentiometry, Tafel lines and electrochemical impedance spectroscopy), this experimental work investigated the effect of these Aloe vera (AV) extracts on corrosion inhibition of concrete reinforcing bar (HA, diameter 12mm) immersed in a 0.5M NaCl solution. The results show that Aloe vera extracts have an average corrosion-inhibiting efficacy of around 86% at an optimum concentration of 20%.展开更多
Over-expression of glutathione S-transferase(GST)can promote Cisplatin resistance in hepatocellular carcinoma(HCC)treatment.Hence,inhibiting GST is an attractive strategy to improve Cisplatin sensitivity in HCC therap...Over-expression of glutathione S-transferase(GST)can promote Cisplatin resistance in hepatocellular carcinoma(HCC)treatment.Hence,inhibiting GST is an attractive strategy to improve Cisplatin sensitivity in HCC therapy.Although several synthesized GST inhibitors have been developed,the side effects and narrow spectrum for anticancer seriously limit their clinical application.Considering the abundance of natural compounds with anticancer activity,this study developed a rapid fluorescence technique to screen“green”natural GST inhibitors with high specificity.The fluorescence assay demonstrated that schisanlactone B(hereafter abbreviated as C1)isolated from Xue tong significantly down-regulated GST levels in Cisplatin-resistant HCC cells in vitro and in vivo.Importantly,C1 can selectively kill HCC cells from normal liver cells,effectively improving the therapeutic effect of Cisplatin on HCC mice by downregulating GST expression.Considering the high GST levels in HCC patients,this compound demonstrated the high potential for sensitizing HCC therapy in clinical practice by down-regulating GST levels.展开更多
The ability of Cocos nucifera L.water（CW） as non-toxic corrosion inhibitor for acid corrosion of aluminium in 0.5 mol/L HCl has been studied using chemical technique.CW shows significant inhibition as corrosion inhi...The ability of Cocos nucifera L.water（CW） as non-toxic corrosion inhibitor for acid corrosion of aluminium in 0.5 mol/L HCl has been studied using chemical technique.CW shows significant inhibition as corrosion inhibitor,with 93%efficiency at the highest concentration of the inhibitor.The inhibitive action is attributed to the adsorption of the inhibitor molecules on metal surface following Langmuir adsorption isotherm.展开更多
文摘Most reinforced concrete structures in seaside locations suffer from corrosion damage to the reinforcement, limiting their durability and necessitating costly repairs. To improve their performance and durability, we have investigated in this paper Aloe vera extracts as a green corrosion inhibitor for reinforcing steel in NaCl environments. Using electrochemical methods (zero-intensity chronopotentiometry, Tafel lines and electrochemical impedance spectroscopy), this experimental work investigated the effect of these Aloe vera (AV) extracts on corrosion inhibition of concrete reinforcing bar (HA, diameter 12mm) immersed in a 0.5M NaCl solution. The results show that Aloe vera extracts have an average corrosion-inhibiting efficacy of around 86% at an optimum concentration of 20%.
基金supported by the National Natural Science Foundation of China(Grant Nos.:82003931,82204766 and 81374062)the Outstanding Youth Foundation of Hunan Provincial Education Department of China(Grant No.:20B445)+3 种基金the Hunan Youth Science and Technology Innovation Talents Project,China(Grant No.:2021RC3100)the Chinese Postdoctoral Science foundation(Grant No.:2021M690974)Changjiang Scholars Program in Ministry Education,People's Republic of China(Program No.:T2019133)the Scientific Research Project of Hunan Provincial Education Department(Project No.:21B0394).
文摘Over-expression of glutathione S-transferase(GST)can promote Cisplatin resistance in hepatocellular carcinoma(HCC)treatment.Hence,inhibiting GST is an attractive strategy to improve Cisplatin sensitivity in HCC therapy.Although several synthesized GST inhibitors have been developed,the side effects and narrow spectrum for anticancer seriously limit their clinical application.Considering the abundance of natural compounds with anticancer activity,this study developed a rapid fluorescence technique to screen“green”natural GST inhibitors with high specificity.The fluorescence assay demonstrated that schisanlactone B(hereafter abbreviated as C1)isolated from Xue tong significantly down-regulated GST levels in Cisplatin-resistant HCC cells in vitro and in vivo.Importantly,C1 can selectively kill HCC cells from normal liver cells,effectively improving the therapeutic effect of Cisplatin on HCC mice by downregulating GST expression.Considering the high GST levels in HCC patients,this compound demonstrated the high potential for sensitizing HCC therapy in clinical practice by down-regulating GST levels.
文摘The ability of Cocos nucifera L.water（CW） as non-toxic corrosion inhibitor for acid corrosion of aluminium in 0.5 mol/L HCl has been studied using chemical technique.CW shows significant inhibition as corrosion inhibitor,with 93%efficiency at the highest concentration of the inhibitor.The inhibitive action is attributed to the adsorption of the inhibitor molecules on metal surface following Langmuir adsorption isotherm.
