目的探讨高分辨三维快速扰相梯度回波(3D-FSPGR)序列显示膝关节区域胫神经及腓总神经的临床应用价值。方法随机收集20名健康志愿者,采用3D-FSPGR序列行单侧膝关节MRI扫描,分别分析胫神经及腓总神经显示率、图像质量主观评分、神经的信...目的探讨高分辨三维快速扰相梯度回波(3D-FSPGR)序列显示膝关节区域胫神经及腓总神经的临床应用价值。方法随机收集20名健康志愿者,采用3D-FSPGR序列行单侧膝关节MRI扫描,分别分析胫神经及腓总神经显示率、图像质量主观评分、神经的信号噪音比(SNR)、神经与周围脂肪对比噪音比(CNR)。结果3D-FSPGR序列图像胫神经及腓总神经的显示率均为100%,图像中脂肪组织及骨骼呈明显的低信号,肌肉呈等信号,腓总神经呈相对于肌肉组织的等信号,胫神经信号略低于腓总神经;两个观察者对胫神经图像质量评分分别为(3.90±0.308&3.85±0.366,κ=0.774),腓总神经图像质量评分分别为(3.80±0.410&3.65±0.489,κ=0.634),两观察者图像质量主观评分一致性较强;相同层面腓总神经SNR及CNR高于胫神经,SNR(TN:CPN=55.90±14.777&78.22±22.937,P=0.000),C N R(T N:C P N=24.31±8.303&46.63±15.523,P=0.000),P值小于0.05两者差异有统计学意义。结论高分辨轴位3D-FSPGR序列可以清晰显示胫神经、腓总神经解剖及其内部细微神经纤维束。展开更多
目的:探讨三维扰相梯度回波序列(3D-FS-SPGR)显示膝关节前外侧韧带结构的的可行性。方法:招募9例成年志愿者(A组)和10例临床不同程度膝关节旋转受限病人(B组)。采用1.5T超导型磁共振扫描系统(HDxt,GE医疗公司)和膝关节专用线圈(Quadknee...目的:探讨三维扰相梯度回波序列(3D-FS-SPGR)显示膝关节前外侧韧带结构的的可行性。方法:招募9例成年志愿者(A组)和10例临床不同程度膝关节旋转受限病人(B组)。采用1.5T超导型磁共振扫描系统(HDxt,GE医疗公司)和膝关节专用线圈(Quadknee)进彳亍扫描。使用3D Slicer重建出前外侧韧带较完整的冠状位图像,分别测量其长度、厚度,求其平均值。比较COR-3D-FS-SPGR序列和COR-2D-FS-T2序列对前外侧韧带的显示情况,P v 0.05被认为有统计学意义。结果膝关节前外侧韧带各部分在COR-3D-FS-SPGR序列显示情况较好,在COR-2D-FS-T2序列显示情况较差,两个序列在膝关节前外侧韧带显示率方面的差异有统计学意义(PV0.05)。A组、B组两组膝关节前外侧韧带在COR-3D-FS-SPGR序列的显示情况无差异(P>0.05);A组、B组两组膝关节前外侧韧带在COR-2D-FS-T2序列的显示情况有差异(P<0.05)。结论应用3D-FS-SPGR序列应显示膝关节前外侧韧带可行,前外侧韧带各个部分显示率比COR-2D-FS-T2序列高。展开更多
Previous neuropathological studies regarding traumatic brain injury have primarily focused on changes in large structures, for example, the clinical prognosis after cerebral contusion, intrace- rebral hematoma, and ep...Previous neuropathological studies regarding traumatic brain injury have primarily focused on changes in large structures, for example, the clinical prognosis after cerebral contusion, intrace- rebral hematoma, and epidural and subdural hematoma. In fact, many smaller injuries can also lead to severe neurological disorders. For example, cerebral microbleeds result in the dysfunc- tion of adjacent neurons and the disassociation between cortex and subcortical structures. These tiny changes cannot be adequately visualized on CT or conventional MRI. In contrast, gradient echo sequence-based susceptibility-weighted imaging is very sensitive to blood metabolites and microbleeds, and can be used to evaluate traumatic cerebral microbleeds with high sensitivity and accuracy. Cerebral microbleed can be considered as an important imaging marker for dif- fuse axonal injury with potential relevance for prognosis. For this reason, based on experimental and clinical studies, this study reviews the role of imaging data showing traumatic cerebral microbleeds in the evaluation of cerebral neuronal injury and neurofunctional loss.展开更多
文摘目的探讨高分辨三维快速扰相梯度回波(3D-FSPGR)序列显示膝关节区域胫神经及腓总神经的临床应用价值。方法随机收集20名健康志愿者,采用3D-FSPGR序列行单侧膝关节MRI扫描,分别分析胫神经及腓总神经显示率、图像质量主观评分、神经的信号噪音比(SNR)、神经与周围脂肪对比噪音比(CNR)。结果3D-FSPGR序列图像胫神经及腓总神经的显示率均为100%,图像中脂肪组织及骨骼呈明显的低信号,肌肉呈等信号,腓总神经呈相对于肌肉组织的等信号,胫神经信号略低于腓总神经;两个观察者对胫神经图像质量评分分别为(3.90±0.308&3.85±0.366,κ=0.774),腓总神经图像质量评分分别为(3.80±0.410&3.65±0.489,κ=0.634),两观察者图像质量主观评分一致性较强;相同层面腓总神经SNR及CNR高于胫神经,SNR(TN:CPN=55.90±14.777&78.22±22.937,P=0.000),C N R(T N:C P N=24.31±8.303&46.63±15.523,P=0.000),P值小于0.05两者差异有统计学意义。结论高分辨轴位3D-FSPGR序列可以清晰显示胫神经、腓总神经解剖及其内部细微神经纤维束。
文摘目的:探讨三维扰相梯度回波序列(3D-FS-SPGR)显示膝关节前外侧韧带结构的的可行性。方法:招募9例成年志愿者(A组)和10例临床不同程度膝关节旋转受限病人(B组)。采用1.5T超导型磁共振扫描系统(HDxt,GE医疗公司)和膝关节专用线圈(Quadknee)进彳亍扫描。使用3D Slicer重建出前外侧韧带较完整的冠状位图像,分别测量其长度、厚度,求其平均值。比较COR-3D-FS-SPGR序列和COR-2D-FS-T2序列对前外侧韧带的显示情况,P v 0.05被认为有统计学意义。结果膝关节前外侧韧带各部分在COR-3D-FS-SPGR序列显示情况较好,在COR-2D-FS-T2序列显示情况较差,两个序列在膝关节前外侧韧带显示率方面的差异有统计学意义(PV0.05)。A组、B组两组膝关节前外侧韧带在COR-3D-FS-SPGR序列的显示情况无差异(P>0.05);A组、B组两组膝关节前外侧韧带在COR-2D-FS-T2序列的显示情况有差异(P<0.05)。结论应用3D-FS-SPGR序列应显示膝关节前外侧韧带可行,前外侧韧带各个部分显示率比COR-2D-FS-T2序列高。
基金supported by grants from the State-Funded Construction Projects Key Clinical Specialist(2013-2015)the Hunan Provincial Science and Technology Department,No.2009FJ3092
文摘Previous neuropathological studies regarding traumatic brain injury have primarily focused on changes in large structures, for example, the clinical prognosis after cerebral contusion, intrace- rebral hematoma, and epidural and subdural hematoma. In fact, many smaller injuries can also lead to severe neurological disorders. For example, cerebral microbleeds result in the dysfunc- tion of adjacent neurons and the disassociation between cortex and subcortical structures. These tiny changes cannot be adequately visualized on CT or conventional MRI. In contrast, gradient echo sequence-based susceptibility-weighted imaging is very sensitive to blood metabolites and microbleeds, and can be used to evaluate traumatic cerebral microbleeds with high sensitivity and accuracy. Cerebral microbleed can be considered as an important imaging marker for dif- fuse axonal injury with potential relevance for prognosis. For this reason, based on experimental and clinical studies, this study reviews the role of imaging data showing traumatic cerebral microbleeds in the evaluation of cerebral neuronal injury and neurofunctional loss.
