A radical-mediated method was reported for diastereoselective synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-1,4-dihydropyridine(DHP)reagents.These DHP...A radical-mediated method was reported for diastereoselective synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-1,4-dihydropyridine(DHP)reagents.These DHP reagents serve as convenient precursors for various glycosyl radicals under the activation of single electron transfer(SET)oxidation by persulfate and visible light irradiation with or without photocatalyst.展开更多
基金This work was supported by the National Natural Science Foundation of China(21672105,21725204,91753124)Natural Science Foundation of Tianjin(17JCYBJC19700,18JCZDJC32800)the Fundamental Research Funds for the Central Universities(Nankai University)(63191746).
文摘A radical-mediated method was reported for diastereoselective synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-1,4-dihydropyridine(DHP)reagents.These DHP reagents serve as convenient precursors for various glycosyl radicals under the activation of single electron transfer(SET)oxidation by persulfate and visible light irradiation with or without photocatalyst.
