By means of solvent extraction and repeated chromatography on silica gel, Sephadex LH-20, HPLC, and preparative TLC, the ethanol extract of the stems of Homalium ceylanicum（Flacourtiaceae/Salicaceae sensu lato） was ...By means of solvent extraction and repeated chromatography on silica gel, Sephadex LH-20, HPLC, and preparative TLC, the ethanol extract of the stems of Homalium ceylanicum（Flacourtiaceae/Salicaceae sensu lato） was chemically investigated, which led to the isolation of 13 constituents, including five lignans（1–5） and three isocoumarins（6–8）. Based on the spectroscopic analysis and comparison of its 1H NMR and 13C NMR data with those in literatures, their structures were identified as（–）-5＇-methoxyisolariciresinol 3α-O-β-D-glucopyranoside（1）,（＋）-lyoniresinol 3α-O-β-D-glucopyranoside（2）,（＋）-isolarisiresinol 3α-O-β-Dglucopyranoside（3）,（–）-isolarisiresinol 3α-O-β-D-glucopyranoside（4）, icariside E5（5）, 3-phenylisocoumarin（6）, homalicine（7）,（–）-dihydrohomalicine（8）, friedelin（9）, 4-hydroxybenzoic acid（10）, catechol（11）, methyl-α-arabinofuranoside（12）, and uridine（13）. All isolates except compounds 6–8 were described from this genus for the first time. Compound 6 was isolated from this species for the first time.展开更多
Aim To study the chemical constituents from the stems of Xylosma controversum Clos. Methods The constituents were isolated by solvent extraction, repeated chromatography with silica gel, Sephadex LH-20, and RP-18 colu...Aim To study the chemical constituents from the stems of Xylosma controversum Clos. Methods The constituents were isolated by solvent extraction, repeated chromatography with silica gel, Sephadex LH-20, and RP-18 columns. The structures were elucidated by spectral analysis. Results Thirteen compounds were isolated and their structures were identified as （-）-syringaresinol （1）, syringaresinol-4-O-β-D-glucopyranoside （2）, syringaresinol-4,4′-bis-O-β-D-glucopyranoside （3）, （±）-catechin （4）, catechin-3-O- β-D-glucopyranoside （5）, catechin-5-O-β-D-glucopyranoside （6）, 1,3-bis-（4-hydroxy-3,5-dimethoxyphenyl）-1,3-propanediol （7）, （R）-（＋）-chaulmoogric acid （8）, friedelin （9）, uracile （10）, benzoic acid （11）, vaniUic acid （12）, and 4-hydroxybenzoic acid （13）. Conclusion All the compounds described above were isolated from this genus for the first time.展开更多
To investigate the chemical components of the barks and twigs ofltoa orientalis. A new linear monoterpene glycoside named itoside O was isolated from the crude extract of Itoa orientalis together with 11 known compoun...To investigate the chemical components of the barks and twigs ofltoa orientalis. A new linear monoterpene glycoside named itoside O was isolated from the crude extract of Itoa orientalis together with 11 known compounds. The new compound was identified to be 3,7-dimethyl-1, 6-octadien-3, 10-dihydroxyl-10-O-α-L-arabinopyranosyl （1 -→6）-O-β-D-glucopyranoside by 1D and 2D NMR analysis, and all known compounds were isolated from this plant for the first time.展开更多
To investigate the chemical components from the stems of Casearia velutina Bl.,the constituents were isolated by repeated chromatography with silica gel,Sephadex LH-20,and ODS columns.The structures were elucidated by...To investigate the chemical components from the stems of Casearia velutina Bl.,the constituents were isolated by repeated chromatography with silica gel,Sephadex LH-20,and ODS columns.The structures were elucidated by spectroscopic analysis.Eleven triterpenoids and its glycosides were isolated from the crude extract of C.velutina,and their structures were identified as friedelin-2,3-lactone（1）,friedelane（2）,epifriedelanol（3）,friedelin（4）,2α,3α,19α-trihydroxy-urs-12-en-28-oic acid（5）,2α,3β,19α-trihydroxy-urs-12-en-28-oic acid（6）,2α,3α,23-trihydroxy-urs-12-en-28-oic acid（7）,2α,3α,23-trihydroxy-olean-12-en-28-oic acid（8）,2α,3α,19α,23-tetrahydroxy-urs-12-en-28-oic acid（9）,2α,3α,19α,23-tetrahydroxy-urs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester（10）,and 3β,19α-dihydroxy-urs-12-en-28-oic acid 3-O-α-L-arabinopyranoside（11）.All the compounds described above were isolated from this species for the first time.Compound 1 is a rarely occurred seco-friedelolactone in Flacourtiaceae.展开更多
基金Program for Changjiang Scholar and Innovative Tea m in University(Grant No.985-2-063-112)
文摘By means of solvent extraction and repeated chromatography on silica gel, Sephadex LH-20, HPLC, and preparative TLC, the ethanol extract of the stems of Homalium ceylanicum（Flacourtiaceae/Salicaceae sensu lato） was chemically investigated, which led to the isolation of 13 constituents, including five lignans（1–5） and three isocoumarins（6–8）. Based on the spectroscopic analysis and comparison of its 1H NMR and 13C NMR data with those in literatures, their structures were identified as（–）-5＇-methoxyisolariciresinol 3α-O-β-D-glucopyranoside（1）,（＋）-lyoniresinol 3α-O-β-D-glucopyranoside（2）,（＋）-isolarisiresinol 3α-O-β-Dglucopyranoside（3）,（–）-isolarisiresinol 3α-O-β-D-glucopyranoside（4）, icariside E5（5）, 3-phenylisocoumarin（6）, homalicine（7）,（–）-dihydrohomalicine（8）, friedelin（9）, 4-hydroxybenzoic acid（10）, catechol（11）, methyl-α-arabinofuranoside（12）, and uridine（13）. All isolates except compounds 6–8 were described from this genus for the first time. Compound 6 was isolated from this species for the first time.
基金Program for Changjiang Scholar and InnovativeTeam in Peking University (Grant number: 985-2-063-112).
文摘Aim To study the chemical constituents from the stems of Xylosma controversum Clos. Methods The constituents were isolated by solvent extraction, repeated chromatography with silica gel, Sephadex LH-20, and RP-18 columns. The structures were elucidated by spectral analysis. Results Thirteen compounds were isolated and their structures were identified as （-）-syringaresinol （1）, syringaresinol-4-O-β-D-glucopyranoside （2）, syringaresinol-4,4′-bis-O-β-D-glucopyranoside （3）, （±）-catechin （4）, catechin-3-O- β-D-glucopyranoside （5）, catechin-5-O-β-D-glucopyranoside （6）, 1,3-bis-（4-hydroxy-3,5-dimethoxyphenyl）-1,3-propanediol （7）, （R）-（＋）-chaulmoogric acid （8）, friedelin （9）, uracile （10）, benzoic acid （11）, vaniUic acid （12）, and 4-hydroxybenzoic acid （13）. Conclusion All the compounds described above were isolated from this genus for the first time.
基金Program for Changjiang Scholar and Innovative Team in University (Grant No. 985-2-063-112)
文摘To investigate the chemical components of the barks and twigs ofltoa orientalis. A new linear monoterpene glycoside named itoside O was isolated from the crude extract of Itoa orientalis together with 11 known compounds. The new compound was identified to be 3,7-dimethyl-1, 6-octadien-3, 10-dihydroxyl-10-O-α-L-arabinopyranosyl （1 -→6）-O-β-D-glucopyranoside by 1D and 2D NMR analysis, and all known compounds were isolated from this plant for the first time.
基金Changjiang Scholar and Innovative Team in University (Grant No. 985-2-063-112)
文摘To investigate the chemical components from the stems of Casearia velutina Bl.,the constituents were isolated by repeated chromatography with silica gel,Sephadex LH-20,and ODS columns.The structures were elucidated by spectroscopic analysis.Eleven triterpenoids and its glycosides were isolated from the crude extract of C.velutina,and their structures were identified as friedelin-2,3-lactone（1）,friedelane（2）,epifriedelanol（3）,friedelin（4）,2α,3α,19α-trihydroxy-urs-12-en-28-oic acid（5）,2α,3β,19α-trihydroxy-urs-12-en-28-oic acid（6）,2α,3α,23-trihydroxy-urs-12-en-28-oic acid（7）,2α,3α,23-trihydroxy-olean-12-en-28-oic acid（8）,2α,3α,19α,23-tetrahydroxy-urs-12-en-28-oic acid（9）,2α,3α,19α,23-tetrahydroxy-urs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester（10）,and 3β,19α-dihydroxy-urs-12-en-28-oic acid 3-O-α-L-arabinopyranoside（11）.All the compounds described above were isolated from this species for the first time.Compound 1 is a rarely occurred seco-friedelolactone in Flacourtiaceae.
