根据中国渔业统计年鉴1956—2014年中国北方三省一市(河北省、辽宁省、山东省和天津市)的捕捞量统计资料,综合分析了黄、渤海海域38种主要渔获种类的平均营养级、渔获量及渔获组成的长期变化情况,并结合FIB指数(Fishing in Balance Inde...根据中国渔业统计年鉴1956—2014年中国北方三省一市(河北省、辽宁省、山东省和天津市)的捕捞量统计资料,综合分析了黄、渤海海域38种主要渔获种类的平均营养级、渔获量及渔获组成的长期变化情况,并结合FIB指数(Fishing in Balance Index),深入探讨黄、渤海渔业状况的年间变化。研究表明,1956—2014年黄、渤海渔获物平均营养级在3.63~4.46的范围内波动,整体呈下降趋势。大致可分为4个阶段:(1)1956—1969年,平均营养级整体呈下降趋势,在1957年达到历史最高点4.46,1969年下降到3.83;(2)1970—1975年,整体呈上升趋势,在1975年上升到第三个高峰值4.32;(3)1976—1997年,整体呈下降趋势,平均营养级在波动中逐渐下降,1992年达到历史最低点3.63;(4)1998—2014年,整体有小幅度上升,最终稳定在3.83左右。FIB指数整体呈先下降后上升的趋势。1956—1968年,FIB指数经过一个振荡后逐渐下降到最低点-1.57;1969—2006年,FIB指数整体在波动中逐渐上升至最高点1.78;2007—2014年,FIB指数下降后趋于稳定。渔获量的长期变化显示,近几十年间黄、渤海高营养级和中低营养级种类的渔获量均呈上升趋势,但高营养级种类所占比例下降,中低营养级种类所占比例上升。与全球及其它海域相比,黄、渤海渔获物平均营养级的下降幅度和下降速率均高于全球平均水平和葡萄牙海域,但低于南澳大利亚和东海海域。展开更多
AIM: To verify the usefulness of FibroQ for predicting fi brosis in patients with chronic hepatitis C, compared with other noninvasive tests. METHODS: This retrospective cohort study included 237 consecutive patients ...AIM: To verify the usefulness of FibroQ for predicting fi brosis in patients with chronic hepatitis C, compared with other noninvasive tests. METHODS: This retrospective cohort study included 237 consecutive patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment. FibroQ, aspartate aminotransferase (AST)/alanine aminotransferase ratio (AAR), AST to platelet ratioindex, cirrhosis discriminant score, age-platelet index (API), Pohl score, FIB-4 index, and Lok's model were calculated and compared. RESULTS: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced (analysis of variance test: P < 0.001). FibroQ trended to be superior in predicting signifi cant fi brosis score in chronic hepatitis C compared with other noninvasive tests. CONCLUSION: FibroQ is a simple and useful test for predicting signifi cant fi brosis in patients with chronic hepatitis C.展开更多
AIM To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index(APRI), and liver stiffness measurement(LSM) in patients with hepatitis B virus infection who have persistently normal ala...AIM To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index(APRI), and liver stiffness measurement(LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase(PNALT).METHODS We enrolled 245 patients with chronic hepatitis B: 95 in PNALT group, 86 in intermittently elevated alanine transaminase(PIALT1) group [alanine transaminase(ALT) within 1-2 × upper limit of normal value(ULN)], and 64 in PIALT2 group(ALT > 2 × ULN). All the patients received a percutaneous liver biopsy guided by ultrasonography. LSM, biochemical tests, and complete blood cell counts were performed.RESULTS The pathological examination revealed moderate inflammatory necrosis ratios of 16.81%(16/95), 32.56%(28/86), and 45.31%(28/64), and moderate liverfibrosis of 24.2%(23/95), 33.72%(29/86), and 43.75%(28/64) in the PNALT, PIALT1, and PIALT2 groups, respectively. The degrees of inflammation and liver fibrosis were significantly higher in the PIALT groups than in the PNALT group(P < 0.05). No significant difference was found in the areas under the curve(AUCs) between APRI and FIB-4 in the PNALT group; however, significant differences were found between APRI and LSM, and between FIB-4 and LSM in the PNALT group(P < 0.05 for both). In the PIALT1 and PIALT2 groups, no significant difference(P > 0.05) was found in AUCs for all comparisons(P > 0.05 for all). In the overall patients, a significant difference in the AUCs was found only between LSM and APRI(P < 0.05).CONCLUSION APRI and FIB-4 are not the ideal noninvasive hepatic fibrosis markers for PNALT patients. LSM is superior to APRI and FIB-4 in PNALT patients because of the influence of liver inflammation and necrosis.展开更多
文摘为了解中东大西洋渔业产区渔获物的资源状况,根据世界粮农组织(FAO)提供的该海域1950—2019年的渔获量数据,结合渔获种类的平均营养级(mean trophic level,MTL)信息,运用统计学方法分析70年间渔获物平均营养级和营养级平衡指数(fishing in balance,FiB)的变动规律,以掌握该海域渔业资源的可持续利用情况。结果显示,MTL大致可分为4个阶段,1950—1956年,MTL指数在3.20左右,无明显变化;1957—1963年,MTL指数迅速上升至3.44;1964—1996年,MTL在波动中趋于下降,历史最高值(3.54)出现在1985年;1997—2019年,MTL稳定在较高水平,其中2018年为该阶段最低点3.35。FiB指数整体呈上升趋势,1950—1956年,FiB指数呈小幅波动增加;1957—1974年,FiB指数显著上升;1975—1996年,FiB指数呈平稳波动状态;1997—2019年,FiB指数整体呈小幅增长趋势。结果表明,中东大西洋海洋生态系统相对稳定,但潜在的渔业资源量越来越少,开发潜力有限。
文摘根据中国渔业统计年鉴1956—2014年中国北方三省一市(河北省、辽宁省、山东省和天津市)的捕捞量统计资料,综合分析了黄、渤海海域38种主要渔获种类的平均营养级、渔获量及渔获组成的长期变化情况,并结合FIB指数(Fishing in Balance Index),深入探讨黄、渤海渔业状况的年间变化。研究表明,1956—2014年黄、渤海渔获物平均营养级在3.63~4.46的范围内波动,整体呈下降趋势。大致可分为4个阶段:(1)1956—1969年,平均营养级整体呈下降趋势,在1957年达到历史最高点4.46,1969年下降到3.83;(2)1970—1975年,整体呈上升趋势,在1975年上升到第三个高峰值4.32;(3)1976—1997年,整体呈下降趋势,平均营养级在波动中逐渐下降,1992年达到历史最低点3.63;(4)1998—2014年,整体有小幅度上升,最终稳定在3.83左右。FIB指数整体呈先下降后上升的趋势。1956—1968年,FIB指数经过一个振荡后逐渐下降到最低点-1.57;1969—2006年,FIB指数整体在波动中逐渐上升至最高点1.78;2007—2014年,FIB指数下降后趋于稳定。渔获量的长期变化显示,近几十年间黄、渤海高营养级和中低营养级种类的渔获量均呈上升趋势,但高营养级种类所占比例下降,中低营养级种类所占比例上升。与全球及其它海域相比,黄、渤海渔获物平均营养级的下降幅度和下降速率均高于全球平均水平和葡萄牙海域,但低于南澳大利亚和东海海域。
基金Supported by Clinical Study Project XMRP, No. CMRPG 690081, from Chiayi Chang Gung Memorial Hospital
文摘AIM: To verify the usefulness of FibroQ for predicting fi brosis in patients with chronic hepatitis C, compared with other noninvasive tests. METHODS: This retrospective cohort study included 237 consecutive patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment. FibroQ, aspartate aminotransferase (AST)/alanine aminotransferase ratio (AAR), AST to platelet ratioindex, cirrhosis discriminant score, age-platelet index (API), Pohl score, FIB-4 index, and Lok's model were calculated and compared. RESULTS: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced (analysis of variance test: P < 0.001). FibroQ trended to be superior in predicting signifi cant fi brosis score in chronic hepatitis C compared with other noninvasive tests. CONCLUSION: FibroQ is a simple and useful test for predicting signifi cant fi brosis in patients with chronic hepatitis C.
文摘AIM To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index(APRI), and liver stiffness measurement(LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase(PNALT).METHODS We enrolled 245 patients with chronic hepatitis B: 95 in PNALT group, 86 in intermittently elevated alanine transaminase(PIALT1) group [alanine transaminase(ALT) within 1-2 × upper limit of normal value(ULN)], and 64 in PIALT2 group(ALT > 2 × ULN). All the patients received a percutaneous liver biopsy guided by ultrasonography. LSM, biochemical tests, and complete blood cell counts were performed.RESULTS The pathological examination revealed moderate inflammatory necrosis ratios of 16.81%(16/95), 32.56%(28/86), and 45.31%(28/64), and moderate liverfibrosis of 24.2%(23/95), 33.72%(29/86), and 43.75%(28/64) in the PNALT, PIALT1, and PIALT2 groups, respectively. The degrees of inflammation and liver fibrosis were significantly higher in the PIALT groups than in the PNALT group(P < 0.05). No significant difference was found in the areas under the curve(AUCs) between APRI and FIB-4 in the PNALT group; however, significant differences were found between APRI and LSM, and between FIB-4 and LSM in the PNALT group(P < 0.05 for both). In the PIALT1 and PIALT2 groups, no significant difference(P > 0.05) was found in AUCs for all comparisons(P > 0.05 for all). In the overall patients, a significant difference in the AUCs was found only between LSM and APRI(P < 0.05).CONCLUSION APRI and FIB-4 are not the ideal noninvasive hepatic fibrosis markers for PNALT patients. LSM is superior to APRI and FIB-4 in PNALT patients because of the influence of liver inflammation and necrosis.
