目的:本研究旨在探讨美容缝合联合剥脱性二氧化碳点阵激光对于颌面部增生性瘢痕的临床效果。方法:本研究选取2015年1月至2019年1月在笔者科室接受治疗的158例颌面部增生性瘢痕患者。所有患者均接受了美容缝合联合剥脱性二氧化碳点阵激...目的:本研究旨在探讨美容缝合联合剥脱性二氧化碳点阵激光对于颌面部增生性瘢痕的临床效果。方法:本研究选取2015年1月至2019年1月在笔者科室接受治疗的158例颌面部增生性瘢痕患者。所有患者均接受了美容缝合联合剥脱性二氧化碳点阵激光治疗,在治疗前和治疗后6个月采用温哥华瘢痕量表(Vancouver scar scale,VSS)、北卡罗来纳大学(the University of North Carolina,UNC)瘢痕量表、患者满意度来评估临床效果。结果:治疗前VSS评分为(9.35±1.82)分高于治疗后6个月的(3.12±1.04)分,治疗前UNC瘢痕量表评分为(8.03±1.45)分高于治疗后6个月的(1.62±0.72)分,差异均有统计学意义(P<0.05)。患者的总体满意率为100%,所有患者均未发生长期并发症。结论:美容缝合联合剥脱性二氧化碳点阵激光能够有效地治疗颌面部增生性瘢痕,效果满意。展开更多
AIM: To investigate low intensity laser irradiation phototherapy(LILIP) on the proliferation, mineralization and degradation of dental pulp constructs.METHODS: Stem cells from human exfoliated deciduous teeth(SHED) we...AIM: To investigate low intensity laser irradiation phototherapy(LILIP) on the proliferation, mineralization and degradation of dental pulp constructs.METHODS: Stem cells from human exfoliated deciduous teeth(SHED) were grown to confluence and seeded on collagen scaffolds to create dental pulp constructs. LILIP was delivered to the dental pulp constructs using an 830 nm GaA IAs laser at an output power of 20 m W. The LILIP energy density was 0.4, 0.8, 1.2, and 2.4 J/cm2. After 8 d, the cell proliferation and degradation within the dental pulp constructs were measured using histologic criteria. After 28 d, the effect of LILIP on SHED mineralization was assessed by von Kossa staining.RESULTS: SHED proliferation within the dental pulp constructs varied after exposure to the 0.4, 0.8, 1.2,and 2.4 J/cm2 LILIP energy densities(P < 0.05). The maximum proliferation of SHED in nutrient deficient media was 218% after exposure to a 1.2 J/cm2 LILIP energy density. SHED grown in nutrient deficient media after exposure to a 0.4, 0.8, and 1.2 J/cm2 LILIP energy density, proliferated by 167-218% compared to the untreated(non-LILIP) control group(P < 0.05).SHED exposed to a 0.4, 0.8, and 1.2 J/cm2 LILIP energy density, and grown in optimal nutritional conditions and proliferated by 147%-164% compared to the untreated(non-LILIP) control group(P < 0.05). The exposure of SHED to the highest LILIP energy density(2.4 J/cm2) caused a reduction of the cell proliferation of up to 73% of the untreated(non-LILIP) control(P < 0.05). The amount of mineral produced by SHED increased over time up to 28 d(P < 0.05). The 0.8 and 1.2J/cm2 LILIP energy densities were the most effective at stimulating the increased the mineralization of the SHED from 150%-700% compared to untreated(nonLILIP) control over 28 d(P < 0.05). The degradation of dental pulp constructs was affected by LILIP(P <0.05). The dental pulp constructs grown in optimal nutritional conditions exposed to a 0.8 J/cm2 or 1.2 J/cm2 LILIP energy density had 13% to 16% more degradation th展开更多
文摘目的:本研究旨在探讨美容缝合联合剥脱性二氧化碳点阵激光对于颌面部增生性瘢痕的临床效果。方法:本研究选取2015年1月至2019年1月在笔者科室接受治疗的158例颌面部增生性瘢痕患者。所有患者均接受了美容缝合联合剥脱性二氧化碳点阵激光治疗,在治疗前和治疗后6个月采用温哥华瘢痕量表(Vancouver scar scale,VSS)、北卡罗来纳大学(the University of North Carolina,UNC)瘢痕量表、患者满意度来评估临床效果。结果:治疗前VSS评分为(9.35±1.82)分高于治疗后6个月的(3.12±1.04)分,治疗前UNC瘢痕量表评分为(8.03±1.45)分高于治疗后6个月的(1.62±0.72)分,差异均有统计学意义(P<0.05)。患者的总体满意率为100%,所有患者均未发生长期并发症。结论:美容缝合联合剥脱性二氧化碳点阵激光能够有效地治疗颌面部增生性瘢痕,效果满意。
文摘AIM: To investigate low intensity laser irradiation phototherapy(LILIP) on the proliferation, mineralization and degradation of dental pulp constructs.METHODS: Stem cells from human exfoliated deciduous teeth(SHED) were grown to confluence and seeded on collagen scaffolds to create dental pulp constructs. LILIP was delivered to the dental pulp constructs using an 830 nm GaA IAs laser at an output power of 20 m W. The LILIP energy density was 0.4, 0.8, 1.2, and 2.4 J/cm2. After 8 d, the cell proliferation and degradation within the dental pulp constructs were measured using histologic criteria. After 28 d, the effect of LILIP on SHED mineralization was assessed by von Kossa staining.RESULTS: SHED proliferation within the dental pulp constructs varied after exposure to the 0.4, 0.8, 1.2,and 2.4 J/cm2 LILIP energy densities(P < 0.05). The maximum proliferation of SHED in nutrient deficient media was 218% after exposure to a 1.2 J/cm2 LILIP energy density. SHED grown in nutrient deficient media after exposure to a 0.4, 0.8, and 1.2 J/cm2 LILIP energy density, proliferated by 167-218% compared to the untreated(non-LILIP) control group(P < 0.05).SHED exposed to a 0.4, 0.8, and 1.2 J/cm2 LILIP energy density, and grown in optimal nutritional conditions and proliferated by 147%-164% compared to the untreated(non-LILIP) control group(P < 0.05). The exposure of SHED to the highest LILIP energy density(2.4 J/cm2) caused a reduction of the cell proliferation of up to 73% of the untreated(non-LILIP) control(P < 0.05). The amount of mineral produced by SHED increased over time up to 28 d(P < 0.05). The 0.8 and 1.2J/cm2 LILIP energy densities were the most effective at stimulating the increased the mineralization of the SHED from 150%-700% compared to untreated(nonLILIP) control over 28 d(P < 0.05). The degradation of dental pulp constructs was affected by LILIP(P <0.05). The dental pulp constructs grown in optimal nutritional conditions exposed to a 0.8 J/cm2 or 1.2 J/cm2 LILIP energy density had 13% to 16% more degradation th
