Abnormal SEP reflects dysfunction of the medial lemniscus and posterior cervical cord. These structures are likely to be affected in Chiari malformation. Therefore, SEP abnormalities may provide valuable information i...Abnormal SEP reflects dysfunction of the medial lemniscus and posterior cervical cord. These structures are likely to be affected in Chiari malformation. Therefore, SEP abnormalities may provide valuable information in patients with CM. However, the consistency of SEP abnormality or normality with the damage is a matter of research. Knowing whether median nerve somatosensory evoked potential (SEP) is useful in revealing subclinical damage in patients with Chiari malformation is important in the treatment and follow-up plan of the disease. The aim of this study was to investigate the relationship between median nerve SEP values and the severity of cerebellar ectopia in patients with Chiari type 1 malformation. Median nerve SEP values were obtained from 30 healthy individuals and 146 individuals with Chiari malformation. The cerebellar ectopia degree and McRae line length were measured. SEP values were not significantly different between groups. The McRae line was found to be significantly shorter in the control group than in the Chiari malformation group (p = 0.031). There was no correlation between the degree of cerebellar ectopia and the length of the McRae line (r = 0.002, p = 0.979). Neither cerebellar ectopy degree nor McRae line length had a relationship with SEP values (r = -0.153, p = 0.066;r = -0.056, p = 0.500, respectively). There was no difference in cerebellar ectopy degree or SEP values between the groups with cerebellar ectopy with and without a syrinx (p = 0.899;p = 0.080, respectively). Likewise, McRae line length was not found to be related to the presence of a syrinx (p = 0.139). Median nerve SEP examination was not beneficial for diagnosing asymptomatic-oligosymptomatic Chiari malformation as a subclinical injury, whether accompanied by syringomyelia or not.展开更多
We point out the issue of differential diagnosis regarding the finding of ectopically localised thymic tissue(a thymic cyst)in the neck.Thymic tissue can be found anywhere along its developmental tract of descent,from...We point out the issue of differential diagnosis regarding the finding of ectopically localised thymic tissue(a thymic cyst)in the neck.Thymic tissue can be found anywhere along its developmental tract of descent,from the angle of the mandible to the upper mediastinum.Disruption of the thymic descent can result in ectopically/abnormally localised islets of accessory thymic tissue,which may undergo cystic changes,as described in a case report by Sun et al.This anatomical variation of the thymus may be clinically misinterpreted as a neoplasm or other congenital anomalies as a branchial cyst,lymphatic malformation or cystic hygroma.The present editorial focuses on the challenge of establishing a diagnosis of ectopically localised tissue of thymus often presented as a lateral cervical mass,especially in the case of cystic variation/degeneration of this thymic tissue.We summarise hypotheses on the origin of such congenital cervical thymic cysts from the point of view of evolutionary history and embryology.We also discuss lesser-known facts about the anatomy,histopathology and developmental biology of the thymus as one of the most enigmatic organs in the human body.展开更多
Introduction: Total unilateral ectopy of the scrotum can be defined by the abnormal congenital anatomical position of the scrotum and its contents. The aim of the study is to describe the diagnostic and therapeutic ap...Introduction: Total unilateral ectopy of the scrotum can be defined by the abnormal congenital anatomical position of the scrotum and its contents. The aim of the study is to describe the diagnostic and therapeutic approach of a total unilateral ectopy of the right scrotum. Methods: This is a clinical observation of a 46-year-old patient with a right abdominal mass evolving from birth. Analyzing the cluster of arguments clinically, operatively and anatomopathologically, allowed us to retain the diagnosis of a total unilateral ectopy of the right scrotum. The informed consent of the patient was obtained before the use of the images for scientific purposes. Conclusion: the unilateral total ectopy of the right scrotum is a rare congenital malformation of the external genitalia, which clinical diagnosis is difficult. Its management is surgical.展开更多
Objective: In our study we aimed to determine the frequency of arrhythmias that we believe may affect driving safety. Methods and Results: Two hundred drivers were randomly selected from the heavy vehicle driver popul...Objective: In our study we aimed to determine the frequency of arrhythmias that we believe may affect driving safety. Methods and Results: Two hundred drivers were randomly selected from the heavy vehicle driver population (82 bus and 118 truck drivers, p = 0.08, q = 0.92, N = 1200, α = 0.01, d = 0.045). A questionnaire was completed via face to face interviews with the individuals including questions about their personal socio-demographic characteristics and symptoms for arrhythmias. An electrocardiography (ECG) was taken of the study participants using the Cardioline Delta 3 Plus Digital ECG machine. The cardiologist at the clinic evaluated the questionnaire and ECG for presence of arrhythmias. When indicated, ambulatory electrocardiography (Holter Monitoring) was performed for 24 hours in 133 individuals (71 driver and 62 control). In cases that had Holter examination;ventricular ectopy was identified in 25.4% and 22.6%, and supra-ventricular ectopy in 45.1% and 35.5% in the driver and the control groups;respectively. Ventricular tachycardia was detected in 2 patients. Arrhythmia frequencies were 59.1%, 54.8% and 57.1% in drivers, control and both groups respectively. Statistical differences between drivers and control group for rhythm disorders were not detected. Conclusions: Arrhythmias with lethal and devastating potential;need to be diagnosed and treated in professional drivers with extreme caution. The follow up and screening for heart diseases has a crucial role in preventing accidents and occupational diseases in drivers.展开更多
文摘Abnormal SEP reflects dysfunction of the medial lemniscus and posterior cervical cord. These structures are likely to be affected in Chiari malformation. Therefore, SEP abnormalities may provide valuable information in patients with CM. However, the consistency of SEP abnormality or normality with the damage is a matter of research. Knowing whether median nerve somatosensory evoked potential (SEP) is useful in revealing subclinical damage in patients with Chiari malformation is important in the treatment and follow-up plan of the disease. The aim of this study was to investigate the relationship between median nerve SEP values and the severity of cerebellar ectopia in patients with Chiari type 1 malformation. Median nerve SEP values were obtained from 30 healthy individuals and 146 individuals with Chiari malformation. The cerebellar ectopia degree and McRae line length were measured. SEP values were not significantly different between groups. The McRae line was found to be significantly shorter in the control group than in the Chiari malformation group (p = 0.031). There was no correlation between the degree of cerebellar ectopia and the length of the McRae line (r = 0.002, p = 0.979). Neither cerebellar ectopy degree nor McRae line length had a relationship with SEP values (r = -0.153, p = 0.066;r = -0.056, p = 0.500, respectively). There was no difference in cerebellar ectopy degree or SEP values between the groups with cerebellar ectopy with and without a syrinx (p = 0.899;p = 0.080, respectively). Likewise, McRae line length was not found to be related to the presence of a syrinx (p = 0.139). Median nerve SEP examination was not beneficial for diagnosing asymptomatic-oligosymptomatic Chiari malformation as a subclinical injury, whether accompanied by syringomyelia or not.
文摘We point out the issue of differential diagnosis regarding the finding of ectopically localised thymic tissue(a thymic cyst)in the neck.Thymic tissue can be found anywhere along its developmental tract of descent,from the angle of the mandible to the upper mediastinum.Disruption of the thymic descent can result in ectopically/abnormally localised islets of accessory thymic tissue,which may undergo cystic changes,as described in a case report by Sun et al.This anatomical variation of the thymus may be clinically misinterpreted as a neoplasm or other congenital anomalies as a branchial cyst,lymphatic malformation or cystic hygroma.The present editorial focuses on the challenge of establishing a diagnosis of ectopically localised tissue of thymus often presented as a lateral cervical mass,especially in the case of cystic variation/degeneration of this thymic tissue.We summarise hypotheses on the origin of such congenital cervical thymic cysts from the point of view of evolutionary history and embryology.We also discuss lesser-known facts about the anatomy,histopathology and developmental biology of the thymus as one of the most enigmatic organs in the human body.
文摘Introduction: Total unilateral ectopy of the scrotum can be defined by the abnormal congenital anatomical position of the scrotum and its contents. The aim of the study is to describe the diagnostic and therapeutic approach of a total unilateral ectopy of the right scrotum. Methods: This is a clinical observation of a 46-year-old patient with a right abdominal mass evolving from birth. Analyzing the cluster of arguments clinically, operatively and anatomopathologically, allowed us to retain the diagnosis of a total unilateral ectopy of the right scrotum. The informed consent of the patient was obtained before the use of the images for scientific purposes. Conclusion: the unilateral total ectopy of the right scrotum is a rare congenital malformation of the external genitalia, which clinical diagnosis is difficult. Its management is surgical.
文摘Objective: In our study we aimed to determine the frequency of arrhythmias that we believe may affect driving safety. Methods and Results: Two hundred drivers were randomly selected from the heavy vehicle driver population (82 bus and 118 truck drivers, p = 0.08, q = 0.92, N = 1200, α = 0.01, d = 0.045). A questionnaire was completed via face to face interviews with the individuals including questions about their personal socio-demographic characteristics and symptoms for arrhythmias. An electrocardiography (ECG) was taken of the study participants using the Cardioline Delta 3 Plus Digital ECG machine. The cardiologist at the clinic evaluated the questionnaire and ECG for presence of arrhythmias. When indicated, ambulatory electrocardiography (Holter Monitoring) was performed for 24 hours in 133 individuals (71 driver and 62 control). In cases that had Holter examination;ventricular ectopy was identified in 25.4% and 22.6%, and supra-ventricular ectopy in 45.1% and 35.5% in the driver and the control groups;respectively. Ventricular tachycardia was detected in 2 patients. Arrhythmia frequencies were 59.1%, 54.8% and 57.1% in drivers, control and both groups respectively. Statistical differences between drivers and control group for rhythm disorders were not detected. Conclusions: Arrhythmias with lethal and devastating potential;need to be diagnosed and treated in professional drivers with extreme caution. The follow up and screening for heart diseases has a crucial role in preventing accidents and occupational diseases in drivers.
