This paper addresses the problem of handling the uncertainty of demand in a one-supplier-one-retailer supply chain system. Demand variation often makes the real production different from what is originally planned, ca...This paper addresses the problem of handling the uncertainty of demand in a one-supplier-one-retailer supply chain system. Demand variation often makes the real production different from what is originally planned, causing a deviation cost from the production plan. Assume the market demand is sensitive to the retail price in a nonlinear form, we show how to effectively handle the demand uncertainty in a supply chain, both for the case of centralized-decision-making system and the case of decentralized-decision-making system with perfect coordination.展开更多
The coordination problem of a supply chain comprising one supplier and one retailer under market demand disruption is studied in this article. A novel exponential demand function is adopted, and the penalty cost is in...The coordination problem of a supply chain comprising one supplier and one retailer under market demand disruption is studied in this article. A novel exponential demand function is adopted, and the penalty cost is introduced explicitly to capture the deviation production cost caused by the market demand disruption. The optimal strategies are obtained for different disruption scale under the centralized mode. For the decentralized mode, it is proved that the supply chain can be fully coordinated by adjusting the price discount policy appropriately when disruption occurs. Furthermore, the authors point out that similar results can be established for more general demand functions that represent different market circumstances if certain assumptions are satisfied.展开更多
Discogenic low back pain is a serious medical and social problem, and accounts for 26%-42% of the patients with chronic low back pain. Recent studies found that the pathologic features of discs obtained from the patie...Discogenic low back pain is a serious medical and social problem, and accounts for 26%-42% of the patients with chronic low back pain. Recent studies found that the pathologic features of discs obtained from the patients with discogenic low back pain were the formation of the zones of vascularized granulation tissue, with extensive innervation in fissures extending from the outer part of the annulus into the nucleus pulposus. Studies suggested that the degeneration of the painful disc might originate from the injury and subsequent repair of annulus fibrosus. Growth factors such as basic fibroblast growth factor, transforming growth factor β1, and connective tissue growth factor, macrophages and mast cells might play a key role in the repair of the injured annulus fibrosus and subsequent disc degeneration. Although there exist controversies about the role of discography as a diagnostic test, provocation discography still is the only available means by which to identify a painful disc. A recent study has classified discogenic low back pain into two types that were annular disruption-induced low back pain and internal endplate disruption-induced low back pain, which have been fully supported by clinical and theoretical bases. Current treatment options for discogenic back pain range from medicinal anti-inflammation strategy to invasive procedures including spine fusion and recently spinal arthroplasty. However, these treatments are limited to relieving symptoms, with no attempt to restore the disc's structure. Recently, there has been a growing interest in developing strategies that aim to repair or regenerate the degenerated disc biologically.展开更多
This paper investigates the problem of how to handling demand disruptions ina one-supplier-one-retailer supply chain, where production cost is a convex function of productionquantity andprice-demand relationship is li...This paper investigates the problem of how to handling demand disruptions ina one-supplier-one-retailer supply chain, where production cost is a convex function of productionquantity andprice-demand relationship is linear. Our results show that, ifdemand is disrupted, underthe new price-demand relationship, all-unit wholesale quantity discount policies combiningcapacitated linear pricingpolicies can also fully coordinate the supply chain.展开更多
超声与碱耦合方法破解污泥,可破坏污泥絮体结构,使污泥胞内外物质进入水相。本试验采用超声与碱耦合方法破解剩余污泥,研究污泥破解过程前后SCOD、pH值以及氨氮的变化。经超声与碱耦合预处理后,污泥上清液SCOD有大幅度提高。当加碱调节...超声与碱耦合方法破解污泥,可破坏污泥絮体结构,使污泥胞内外物质进入水相。本试验采用超声与碱耦合方法破解剩余污泥,研究污泥破解过程前后SCOD、pH值以及氨氮的变化。经超声与碱耦合预处理后,污泥上清液SCOD有大幅度提高。当加碱调节污泥pH为12,超声破解30 m in后,污泥溶液SCOD溶出率从3.96%增加到27.88%。加碱后污泥经超声破解,其pH值有所下降,污泥溶液氨氮值会有所增加,但变化幅度不大。污泥温度随破解时间的延长而明显提高,这有利于后续污泥厌氧消化。展开更多
文摘This paper addresses the problem of handling the uncertainty of demand in a one-supplier-one-retailer supply chain system. Demand variation often makes the real production different from what is originally planned, causing a deviation cost from the production plan. Assume the market demand is sensitive to the retail price in a nonlinear form, we show how to effectively handle the demand uncertainty in a supply chain, both for the case of centralized-decision-making system and the case of decentralized-decision-making system with perfect coordination.
基金This research was supported by National Science Foundation of China (60274048)
文摘The coordination problem of a supply chain comprising one supplier and one retailer under market demand disruption is studied in this article. A novel exponential demand function is adopted, and the penalty cost is introduced explicitly to capture the deviation production cost caused by the market demand disruption. The optimal strategies are obtained for different disruption scale under the centralized mode. For the decentralized mode, it is proved that the supply chain can be fully coordinated by adjusting the price discount policy appropriately when disruption occurs. Furthermore, the authors point out that similar results can be established for more general demand functions that represent different market circumstances if certain assumptions are satisfied.
文摘Discogenic low back pain is a serious medical and social problem, and accounts for 26%-42% of the patients with chronic low back pain. Recent studies found that the pathologic features of discs obtained from the patients with discogenic low back pain were the formation of the zones of vascularized granulation tissue, with extensive innervation in fissures extending from the outer part of the annulus into the nucleus pulposus. Studies suggested that the degeneration of the painful disc might originate from the injury and subsequent repair of annulus fibrosus. Growth factors such as basic fibroblast growth factor, transforming growth factor β1, and connective tissue growth factor, macrophages and mast cells might play a key role in the repair of the injured annulus fibrosus and subsequent disc degeneration. Although there exist controversies about the role of discography as a diagnostic test, provocation discography still is the only available means by which to identify a painful disc. A recent study has classified discogenic low back pain into two types that were annular disruption-induced low back pain and internal endplate disruption-induced low back pain, which have been fully supported by clinical and theoretical bases. Current treatment options for discogenic back pain range from medicinal anti-inflammation strategy to invasive procedures including spine fusion and recently spinal arthroplasty. However, these treatments are limited to relieving symptoms, with no attempt to restore the disc's structure. Recently, there has been a growing interest in developing strategies that aim to repair or regenerate the degenerated disc biologically.
文摘This paper investigates the problem of how to handling demand disruptions ina one-supplier-one-retailer supply chain, where production cost is a convex function of productionquantity andprice-demand relationship is linear. Our results show that, ifdemand is disrupted, underthe new price-demand relationship, all-unit wholesale quantity discount policies combiningcapacitated linear pricingpolicies can also fully coordinate the supply chain.
文摘超声与碱耦合方法破解污泥,可破坏污泥絮体结构,使污泥胞内外物质进入水相。本试验采用超声与碱耦合方法破解剩余污泥,研究污泥破解过程前后SCOD、pH值以及氨氮的变化。经超声与碱耦合预处理后,污泥上清液SCOD有大幅度提高。当加碱调节污泥pH为12,超声破解30 m in后,污泥溶液SCOD溶出率从3.96%增加到27.88%。加碱后污泥经超声破解,其pH值有所下降,污泥溶液氨氮值会有所增加,但变化幅度不大。污泥温度随破解时间的延长而明显提高,这有利于后续污泥厌氧消化。
