AIM:To investigate whether retinal nerve fiber layer defects(RNFLDs)is a potential risk factor for chronic kidney disease(CKD)in Chinese adults.METHODS:The Kailuan Eye Study was a populationbased study that included 1...AIM:To investigate whether retinal nerve fiber layer defects(RNFLDs)is a potential risk factor for chronic kidney disease(CKD)in Chinese adults.METHODS:The Kailuan Eye Study was a populationbased study that included 14440 participants.All participants underwent detailed assessments,RNFLDs were diagnosed using color fundus photographs.RESULTS:Overall,12507 participants[8533 males(68.23%)]had complete systemic examination data and at least one evaluable fundus photograph.RNFLDs were found in 621 participants[5.0%;95%confidence interval(CI):4.6%-5.34%],and 70 cases of multiple RNFLDs were found(11.27%).After adjusting multiple factors,RNFLDs was significantly associated with CKD severity,the ORs of CKD stage 3,stage 4 and stage 5 were 1.698,4.167,and 9.512,respectively.Multiple RNFLDs were also associated with CKD severity after adjusting multiple factors,the ORs of CKD stage 3 and stage 5 were 4.465 and 11.833 respectively.Furthermore,2294 participants had CKD(18.34%,95%CI:17.68%-18.99%).After adjusting for other factors,CKD presence was significantly correlated with the presence of RNFLDs.CONCLUSION:The strongest risk factors for RNFLDs are CKD and hypertension.Conversely,RNFLDs can be an ocular feature in patients with CKD.Fundoscopy can help detect systemic diseases,and assessment for RNFLDs should be considered in CKD patients.展开更多
GaAs太阳电池在空间辐射条件下的性能衰减与电池内部微观结构紧密相关。文章针对空间辐射带质子辐照GaAs材料,利用分子动力学方法研究由被辐射材料中产生的不同能量(0.1~10 ke V)初级离位原子(PKA)引起的级联碰撞过程,分析缺陷随辐照时...GaAs太阳电池在空间辐射条件下的性能衰减与电池内部微观结构紧密相关。文章针对空间辐射带质子辐照GaAs材料,利用分子动力学方法研究由被辐射材料中产生的不同能量(0.1~10 ke V)初级离位原子(PKA)引起的级联碰撞过程,分析缺陷随辐照时间、入射PKA能量的演化规律,探讨点缺陷和缺陷簇的形成特征。研究发现,在GaAs材料的缺陷对数目随时间的演化曲线中,在"离位峰"和稳定状态时,缺陷对数目与PKA能量呈一定的线性关系;PKA能量越高,辐射损伤越严重、越不易恢复,但缺陷复合率随能量升高趋于饱和;点缺陷在GaAs中主要以缺陷簇的方式存在,且随着能量的升高,孤立缺陷倾向于缔合成缺陷簇。展开更多
Oxidation corrosion of steels usually occurs in contact with the oxygen-contained environment, which is accelerated by high oxygen concentration and irradiation. The oxidation mechanism of steels is investigated by th...Oxidation corrosion of steels usually occurs in contact with the oxygen-contained environment, which is accelerated by high oxygen concentration and irradiation. The oxidation mechanism of steels is investigated by the adsorption/solution of oxygen atoms on/under body-centered-cubic(bcc) iron surfaces, and diffusion of oxygen atoms on the surface and in the near-surface region. Energetic results indicate that oxygen atoms prefer to adsorb at hollow and long-bridge positions on the Fe(100) and(110) surfaces, respectively. As the coverage of oxygen atoms increases, oxygen atoms would repel each other and gradually dissolve in the near-surface and bulk region. As vacancies exist, oxygen atoms are attracted by vacancies, especially in the near-surface and bulk region. Dynamic results indicate that the diffusion of O atoms on surfaces is easier than that into near-surface, which is affected by oxygen coverage and vacancies. Moreover, the effects of oxygen concentration and irradiation on oxygen density in the near-surface and bulk region are estimated by the Mc Lean’s model with a simple hypothesis.展开更多
基金Supported by the National Natural Science Foundation of China(No.82220108017,No.82141128)the Capital Health Research and Development of Special(No.2020-1-2052)Science&Technology Project of Beijing Municipal Science&Technology Commission(No.Z201100005520045,No.Z181100001818003).
文摘AIM:To investigate whether retinal nerve fiber layer defects(RNFLDs)is a potential risk factor for chronic kidney disease(CKD)in Chinese adults.METHODS:The Kailuan Eye Study was a populationbased study that included 14440 participants.All participants underwent detailed assessments,RNFLDs were diagnosed using color fundus photographs.RESULTS:Overall,12507 participants[8533 males(68.23%)]had complete systemic examination data and at least one evaluable fundus photograph.RNFLDs were found in 621 participants[5.0%;95%confidence interval(CI):4.6%-5.34%],and 70 cases of multiple RNFLDs were found(11.27%).After adjusting multiple factors,RNFLDs was significantly associated with CKD severity,the ORs of CKD stage 3,stage 4 and stage 5 were 1.698,4.167,and 9.512,respectively.Multiple RNFLDs were also associated with CKD severity after adjusting multiple factors,the ORs of CKD stage 3 and stage 5 were 4.465 and 11.833 respectively.Furthermore,2294 participants had CKD(18.34%,95%CI:17.68%-18.99%).After adjusting for other factors,CKD presence was significantly correlated with the presence of RNFLDs.CONCLUSION:The strongest risk factors for RNFLDs are CKD and hypertension.Conversely,RNFLDs can be an ocular feature in patients with CKD.Fundoscopy can help detect systemic diseases,and assessment for RNFLDs should be considered in CKD patients.
文摘GaAs太阳电池在空间辐射条件下的性能衰减与电池内部微观结构紧密相关。文章针对空间辐射带质子辐照GaAs材料,利用分子动力学方法研究由被辐射材料中产生的不同能量(0.1~10 ke V)初级离位原子(PKA)引起的级联碰撞过程,分析缺陷随辐照时间、入射PKA能量的演化规律,探讨点缺陷和缺陷簇的形成特征。研究发现,在GaAs材料的缺陷对数目随时间的演化曲线中,在"离位峰"和稳定状态时,缺陷对数目与PKA能量呈一定的线性关系;PKA能量越高,辐射损伤越严重、越不易恢复,但缺陷复合率随能量升高趋于饱和;点缺陷在GaAs中主要以缺陷簇的方式存在,且随着能量的升高,孤立缺陷倾向于缔合成缺陷簇。
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2017YFE0302400 and 2017YFA0402803)the National Nature Science Foundation of China(Grant Nos.11735015,52071314,51871207,U1832206,12075274,U1967211,52171084)Hefei Advanced Computing Center。
文摘Oxidation corrosion of steels usually occurs in contact with the oxygen-contained environment, which is accelerated by high oxygen concentration and irradiation. The oxidation mechanism of steels is investigated by the adsorption/solution of oxygen atoms on/under body-centered-cubic(bcc) iron surfaces, and diffusion of oxygen atoms on the surface and in the near-surface region. Energetic results indicate that oxygen atoms prefer to adsorb at hollow and long-bridge positions on the Fe(100) and(110) surfaces, respectively. As the coverage of oxygen atoms increases, oxygen atoms would repel each other and gradually dissolve in the near-surface and bulk region. As vacancies exist, oxygen atoms are attracted by vacancies, especially in the near-surface and bulk region. Dynamic results indicate that the diffusion of O atoms on surfaces is easier than that into near-surface, which is affected by oxygen coverage and vacancies. Moreover, the effects of oxygen concentration and irradiation on oxygen density in the near-surface and bulk region are estimated by the Mc Lean’s model with a simple hypothesis.
