Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarctio...Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarction, and assessed outcomes according to the U.S. National Institutes of Health Stroke Score, Modified Rankin Scale, and transcranial magnetic stimulation motor-evoked potential. Compared with the control group, the clinical total effective rate and the cortical potential rise rate of the upper limbs were significantly higher, the central motor conduction time of upper limb was significantly shorter, and the upper limb motor-evoked potential amplitude was significantly increased, in the ozone group. In the ozone group, the National Institutes of Health Stroke Score was positively correlated with the central motor conduction time and the motor-evoked potential amplitude of the upper limb. Central motor conduction time and motor-evoked potential amplitude of the upper limb may be effective indicators of motor-evoked potentials to assess upper limb motor function in cerebral infarct patients. Furthermore, major ozonated autohemotherapy may promote motor function recovery of the upper limb in patients with acute cerebral infarction.展开更多
Based on thermal-entransy theory, the multi-objective constructal design of quadrilateral heat generation body(HGB) with similar shapes of leaves is studied further. The relationship between the aspect ratio of quadri...Based on thermal-entransy theory, the multi-objective constructal design of quadrilateral heat generation body(HGB) with similar shapes of leaves is studied further. The relationship between the aspect ratio of quadrilateral HGB and average temperature difference based on thermal-entransy dissipation is compared with that between the aspect ratio of quadrilateral HGB and the maximum temperature difference(MTD). The relationship between a composite function, consisting of linear weighting sum of the average temperature difference and MTD, and aspect ratio is obtained, and the optimal aspect ratios under minimum composite function with different weighting coefficients are obtained. Using the NSGA-Ⅱ algorithm, the Pareto frontier containing a series of compromise results of average temperature difference and MTD is obtained, and optimization results are compared using the deviation index. There is no aspect ratio to make both MTD and average temperature difference reach the minimum, and the optimal aspect ratio under the minimum MTD is smaller than that under the minimum average temperature difference. The optimal aspect ratio is obtained by making the composite function reach the minimum, and the optimal aspect ratios obtained by minimizing the composite function with different weighting coefficients are different. Compared with the construct of the initial design, the value of the composite function with optimal construct decreases by 1.9%, and the aspect ratio of the quadrilateral HGB decreases by 9.1%. The average temperature difference with the optimal construct increases by 2.1%, and the MTD with the optimal construct decreases by 5.6%. The deviation index under multi-objective optimization is smaller than that under single-objective optimization, and the obtained construct has better comprehensive thermal conductivity. Compared with TOPSIS and LINMAP decision-making methods, the average temperature difference with composite function optimization increases by 0.55% and 0.62% respectively, but the MTD with co展开更多
基金supported by the Guangdong Province Medical Science Research Fund, No. B200258
文摘Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarction, and assessed outcomes according to the U.S. National Institutes of Health Stroke Score, Modified Rankin Scale, and transcranial magnetic stimulation motor-evoked potential. Compared with the control group, the clinical total effective rate and the cortical potential rise rate of the upper limbs were significantly higher, the central motor conduction time of upper limb was significantly shorter, and the upper limb motor-evoked potential amplitude was significantly increased, in the ozone group. In the ozone group, the National Institutes of Health Stroke Score was positively correlated with the central motor conduction time and the motor-evoked potential amplitude of the upper limb. Central motor conduction time and motor-evoked potential amplitude of the upper limb may be effective indicators of motor-evoked potentials to assess upper limb motor function in cerebral infarct patients. Furthermore, major ozonated autohemotherapy may promote motor function recovery of the upper limb in patients with acute cerebral infarction.
基金supported by the National Natural Science Foundation of China(Grant No.52171317)。
文摘Based on thermal-entransy theory, the multi-objective constructal design of quadrilateral heat generation body(HGB) with similar shapes of leaves is studied further. The relationship between the aspect ratio of quadrilateral HGB and average temperature difference based on thermal-entransy dissipation is compared with that between the aspect ratio of quadrilateral HGB and the maximum temperature difference(MTD). The relationship between a composite function, consisting of linear weighting sum of the average temperature difference and MTD, and aspect ratio is obtained, and the optimal aspect ratios under minimum composite function with different weighting coefficients are obtained. Using the NSGA-Ⅱ algorithm, the Pareto frontier containing a series of compromise results of average temperature difference and MTD is obtained, and optimization results are compared using the deviation index. There is no aspect ratio to make both MTD and average temperature difference reach the minimum, and the optimal aspect ratio under the minimum MTD is smaller than that under the minimum average temperature difference. The optimal aspect ratio is obtained by making the composite function reach the minimum, and the optimal aspect ratios obtained by minimizing the composite function with different weighting coefficients are different. Compared with the construct of the initial design, the value of the composite function with optimal construct decreases by 1.9%, and the aspect ratio of the quadrilateral HGB decreases by 9.1%. The average temperature difference with the optimal construct increases by 2.1%, and the MTD with the optimal construct decreases by 5.6%. The deviation index under multi-objective optimization is smaller than that under single-objective optimization, and the obtained construct has better comprehensive thermal conductivity. Compared with TOPSIS and LINMAP decision-making methods, the average temperature difference with composite function optimization increases by 0.55% and 0.62% respectively, but the MTD with co
