目的探讨人体组成成分指标在不同年龄性别间的差异,为更精准的个体化营养及运动管理提供依据。方法选取成年健康体检受检者1 656名,按年龄分为6组:18~29岁组(n=79),30~39岁组(n=346),40~49岁组(n=463),50~59岁组(n=471),60~69岁组(n=236...目的探讨人体组成成分指标在不同年龄性别间的差异,为更精准的个体化营养及运动管理提供依据。方法选取成年健康体检受检者1 656名,按年龄分为6组:18~29岁组(n=79),30~39岁组(n=346),40~49岁组(n=463),50~59岁组(n=471),60~69岁组(n=236),70岁以上组(n=61)。采用In Body 720人体成分分析仪生物电阻抗法检测人体组成成分。结果不同性别者腰臀比,身体水分、蛋白质、矿物质含量,体脂百分比,肌肉量,基础代谢率的分布不同(P<0.05),体质量指数、健康评估得分无差异(P>0.05)。不同年龄组比较发现,男性身体水分含量分布无差异(P>0.05),其余各指标分布有差异(P<0.05);而女性各指标分布均有差异(P<0.05)。基础代谢率在18~39岁间随年龄增长而增高,40岁之后开始下降。体质量指数在18~59岁间随年龄增长而增高,60岁后开始降低。蛋白质、肌肉量、健康评估得分均在50岁之后呈现下降趋势。女性矿物质、肌肉量及身体水分含量随年龄增加而减少,且早于男性。体脂百分比及腰臀比值均随年龄增长而增长,女性增长速度快于男性。结论不同年龄、性别成年受检者人体成分指标有差异。40岁以前是体质量控制的重要年龄段。40岁以后,应随基础代谢率降低而减少能量摄入。女性较男性应更早重视维持机体蛋白质、矿物质含量,增肌减脂,应特别关注腰部减脂。展开更多
This article presents an application of assessing human health risk in typical city of North China plain.Combined with water quality and multi-element analysis,Pb,Cd,Cr^6＋,Mn,NO3^-,F^-,and As in groundwater samples w...This article presents an application of assessing human health risk in typical city of North China plain.Combined with water quality and multi-element analysis,Pb,Cd,Cr^6＋,Mn,NO3^-,F^-,and As in groundwater samples were chosen to be used for human health risk assessment of drinking water pathway and dermal contact pathway,and results show a good effect.Results indicate that（1） poor water quality is caused by salinity and hardness overstandard;（2） in noncarcinogenic risk,samples that do not pose noncarcinogenic risk only account for 28.46%;in carcinogenic risk,samples that do not pose carcinogenic risk account for 73.08%;（3） the noncarcinogenic risk in the study area decreased in the following order：NO3^-〉Mn〉As〉F-〉Cr^6＋〉Cd〉Pb and the carcinogenic risk of the study area de-creased in the following order：As〉Cd=NO3^-=Mn=F-=Cr^6＋=Cd=Pb=0,because the slop factors were not available for the other pollutants,except for As;and（4） in terms of whole study area,the main contrib-ute order of drinking water pathway and dermal contact pathway in human body is drinking water pathway〉dermal contact pathway.展开更多
AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospec...AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis.展开更多
Crab paste is a traditional and popular food for people in the coastal area of China.Visual inspection is currently the only method of quality assessment.We developed a new analytical method of a comprehensive survey ...Crab paste is a traditional and popular food for people in the coastal area of China.Visual inspection is currently the only method of quality assessment.We developed a new analytical method of a comprehensive survey of nutrients and quality assessment for crab paste based on a combination of 1 H NMR spectroscopy with multivariate data analysis.The aqueous extract of crab paste was dominated by amino acids,sugars,carboxylic acids,nucleotides and amines(including 19 first-time-reported compounds such as choline,uracil and guanosine).Two grades of crab paste had significant compositional differences in terms of amino acids,lactate,N-acetylglutamate,choline,dimethylamine,uridine,1-methylnicotinamide and 2-pyridienmethanol.These results provided important information on the grade-dependence of crab-paste composition,and demonstrated that NMR-MDA was effective not only for the comprehensive survey of nutrients,but also for quality assessment of crab paste.展开更多
文摘目的探讨人体组成成分指标在不同年龄性别间的差异,为更精准的个体化营养及运动管理提供依据。方法选取成年健康体检受检者1 656名,按年龄分为6组:18~29岁组(n=79),30~39岁组(n=346),40~49岁组(n=463),50~59岁组(n=471),60~69岁组(n=236),70岁以上组(n=61)。采用In Body 720人体成分分析仪生物电阻抗法检测人体组成成分。结果不同性别者腰臀比,身体水分、蛋白质、矿物质含量,体脂百分比,肌肉量,基础代谢率的分布不同(P<0.05),体质量指数、健康评估得分无差异(P>0.05)。不同年龄组比较发现,男性身体水分含量分布无差异(P>0.05),其余各指标分布有差异(P<0.05);而女性各指标分布均有差异(P<0.05)。基础代谢率在18~39岁间随年龄增长而增高,40岁之后开始下降。体质量指数在18~59岁间随年龄增长而增高,60岁后开始降低。蛋白质、肌肉量、健康评估得分均在50岁之后呈现下降趋势。女性矿物质、肌肉量及身体水分含量随年龄增加而减少,且早于男性。体脂百分比及腰臀比值均随年龄增长而增长,女性增长速度快于男性。结论不同年龄、性别成年受检者人体成分指标有差异。40岁以前是体质量控制的重要年龄段。40岁以后,应随基础代谢率降低而减少能量摄入。女性较男性应更早重视维持机体蛋白质、矿物质含量,增肌减脂,应特别关注腰部减脂。
基金supported by the National Science and Technology Major Project(Nos.2009ZX05039-003, 2009ZX05039-004,and 2011ZX05060-005)the National Program on Key Basic Research Program(No.2010CB428801-1)the State-Owned Land Resources Investigation(No. 1212010430351)
文摘This article presents an application of assessing human health risk in typical city of North China plain.Combined with water quality and multi-element analysis,Pb,Cd,Cr^6＋,Mn,NO3^-,F^-,and As in groundwater samples were chosen to be used for human health risk assessment of drinking water pathway and dermal contact pathway,and results show a good effect.Results indicate that（1） poor water quality is caused by salinity and hardness overstandard;（2） in noncarcinogenic risk,samples that do not pose noncarcinogenic risk only account for 28.46%;in carcinogenic risk,samples that do not pose carcinogenic risk account for 73.08%;（3） the noncarcinogenic risk in the study area decreased in the following order：NO3^-〉Mn〉As〉F-〉Cr^6＋〉Cd〉Pb and the carcinogenic risk of the study area de-creased in the following order：As〉Cd=NO3^-=Mn=F-=Cr^6＋=Cd=Pb=0,because the slop factors were not available for the other pollutants,except for As;and（4） in terms of whole study area,the main contrib-ute order of drinking water pathway and dermal contact pathway in human body is drinking water pathway〉dermal contact pathway.
基金Supported by The Fundacao de Amparo a Pesquisa do Estado de Sao Paulo,Nos.2011/13243-3,2012/15677-3[GB]
文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis.
基金supported by the National Natural Science Foundation of China (31100032)University National Oceanographic Public Welfare Project (201205029)+1 种基金K. C. Wong Magna Fund in Ningbo University and Academic Discipline Project of Ningbo University (xk11089)the National Natural Science Foundation of China (20825520and 20921004) for financial supports
文摘Crab paste is a traditional and popular food for people in the coastal area of China.Visual inspection is currently the only method of quality assessment.We developed a new analytical method of a comprehensive survey of nutrients and quality assessment for crab paste based on a combination of 1 H NMR spectroscopy with multivariate data analysis.The aqueous extract of crab paste was dominated by amino acids,sugars,carboxylic acids,nucleotides and amines(including 19 first-time-reported compounds such as choline,uracil and guanosine).Two grades of crab paste had significant compositional differences in terms of amino acids,lactate,N-acetylglutamate,choline,dimethylamine,uridine,1-methylnicotinamide and 2-pyridienmethanol.These results provided important information on the grade-dependence of crab-paste composition,and demonstrated that NMR-MDA was effective not only for the comprehensive survey of nutrients,but also for quality assessment of crab paste.
