Chinese tonifying herbs, which are classified into four functional categories (namely, Yang, Qi, Yin, Blood) are commonly used for restoring normal body function and the prevention of diseases. To explore cell-based b...Chinese tonifying herbs, which are classified into four functional categories (namely, Yang, Qi, Yin, Blood) are commonly used for restoring normal body function and the prevention of diseases. To explore cell-based biological markers for Blood-enriching Chinese herbs, we investigate the effect of 11 commonly used Blood-enriching herbs on erythropoietin (EPO) production in HepG2 cells. Herbs for nourishing Yin were tested for determining the specificity of Blood-enriching herbs in inducing EPO production. In addition, the effects of Blood-enriching herbs on nitric oxide (NO) production in both HepG2 cells and human umbilical vein endothelial cells (HUVECs) were also investigated. The results indicated that methanolic extracts of Blood-enriching herbs (but not Yin-nourishing herbs) showed characteristic pharmacological activity in inducing EPO production in HepG2 cells and NO release in HUVECs. The experimental findings, therefore, support the use of cell-based EPO production and NO release as biological markers for Blood-enriching Chinese tonifying herbs.展开更多
目的:探讨维药石榴补血糖浆治疗缺铁性贫血的临床疗效及安全性。方法:对2018年9月—2019年6月我院收治的45例缺铁性贫血患者采用石榴补血糖浆进行治疗,3次/d,20 m L/次,口服,疗程1个月。治疗前后均进行血常规检查,并进行中医证候评分,...目的:探讨维药石榴补血糖浆治疗缺铁性贫血的临床疗效及安全性。方法:对2018年9月—2019年6月我院收治的45例缺铁性贫血患者采用石榴补血糖浆进行治疗,3次/d,20 m L/次,口服,疗程1个月。治疗前后均进行血常规检查,并进行中医证候评分,记录不良反应发生率。结果:治疗30 d后,血红蛋白、红细胞计数均较治疗前改善(P<0.05),中医证候评分明显降低(P<0.05)。治疗期间无不良反应发生。结论:石榴补血糖浆治疗缺铁性贫血安全有效。展开更多
文摘Chinese tonifying herbs, which are classified into four functional categories (namely, Yang, Qi, Yin, Blood) are commonly used for restoring normal body function and the prevention of diseases. To explore cell-based biological markers for Blood-enriching Chinese herbs, we investigate the effect of 11 commonly used Blood-enriching herbs on erythropoietin (EPO) production in HepG2 cells. Herbs for nourishing Yin were tested for determining the specificity of Blood-enriching herbs in inducing EPO production. In addition, the effects of Blood-enriching herbs on nitric oxide (NO) production in both HepG2 cells and human umbilical vein endothelial cells (HUVECs) were also investigated. The results indicated that methanolic extracts of Blood-enriching herbs (but not Yin-nourishing herbs) showed characteristic pharmacological activity in inducing EPO production in HepG2 cells and NO release in HUVECs. The experimental findings, therefore, support the use of cell-based EPO production and NO release as biological markers for Blood-enriching Chinese tonifying herbs.
文摘目的:探讨维药石榴补血糖浆治疗缺铁性贫血的临床疗效及安全性。方法:对2018年9月—2019年6月我院收治的45例缺铁性贫血患者采用石榴补血糖浆进行治疗,3次/d,20 m L/次,口服,疗程1个月。治疗前后均进行血常规检查,并进行中医证候评分,记录不良反应发生率。结果:治疗30 d后,血红蛋白、红细胞计数均较治疗前改善(P<0.05),中医证候评分明显降低(P<0.05)。治疗期间无不良反应发生。结论:石榴补血糖浆治疗缺铁性贫血安全有效。
