利用DNAStar Protean软件对热带无爪螨主要致敏原Blo t 5的二级结构和表面特性进行分析,如理化性质、亲水性、表面可及性、可塑性等,预测Blo t 5蛋白的B抗原表位和T抗原表位。实验结果表明,Blo t 5蛋白的二级结构以α螺旋为主,存在6个...利用DNAStar Protean软件对热带无爪螨主要致敏原Blo t 5的二级结构和表面特性进行分析,如理化性质、亲水性、表面可及性、可塑性等,预测Blo t 5蛋白的B抗原表位和T抗原表位。实验结果表明,Blo t 5蛋白的二级结构以α螺旋为主,存在6个潜在的B抗原表位位点,可能的B抗原表位区域有:18-31,39-48,56-77,86-101,105-112,117-133氨基酸残基或其附近。含有7个潜在的T细胞抗原表位区域:32-37,40-44,57-65,70-79,86-95,100-104,115-120氨基酸残基或其附近。笔者应用Protean软件预测了热带无爪螨主要致敏原Blo t 5的抗原表位,为进一步研究Blo t 5致敏原的结构与功能,研制针对热带螨的预防性和治疗性疫苗、开发相应的诊断试剂盒奠定了基础。展开更多
In this paper we study multilinear oscillatory singular integrals with rough kernel and give a criterion of certain boundedness for this kind of operator
Two pointwise estimates relating the maximal multilinear singular integral operators and some classical maximal operators are established. These pointwise estimates imply the rearrangement estimate and the BLO(Rn) est...Two pointwise estimates relating the maximal multilinear singular integral operators and some classical maximal operators are established. These pointwise estimates imply the rearrangement estimate and the BLO(Rn) estimate for the maximal multilinear singular integral operators.展开更多
Correlated radio-optical variations on intraday timescales have been observed （e.g. in BLO 0716＋714） and such radio intraday variability is suggested to have an intrinsic origin. Recently, multi-wavelength observat...Correlated radio-optical variations on intraday timescales have been observed （e.g. in BLO 0716＋714） and such radio intraday variability is suggested to have an intrinsic origin. Recently, multi-wavelength observations, simultaneous at radio, mm-submm, optical and hard X-rays, of 0716＋714, show that during a period of intraday/interday variations at radio and mm wavelengths, the apparent brightness temperature of the source exceeded the Compton-limit （-10^12 K） by 2-4 orders of magnitude, but no Compton catastrophe （or no high luminosity of inverse-Compton radiation） was detected. It is also found that the intraday/interday variations at mm-submm wavelengths are consistent with the evolutionary behavior of a standard synchrotron source and for the intraday/interday variations at centimeter wavelengths opacity effects can play a significant role, which is consistent with the interpretation suggested previously by Qian et al. Thus the apparent high brightness temperatures may probably be explained in terms of Doppler boosting effects due to bulk relativistic motion of the source. We will argue a scenario to simulate the correlations between the radio and optical variations on intraday timescales observed in BLO 0716＋714 in terms of a relativistic shock propagating through a jet with a dual structure.展开更多
目的预测热带无爪螨主要变应原Blo t 21的抗原表位。方法利用DNAStar Protean软件分析热带无爪螨主要变应原Blo t 21的二级结构和表面特性,如理化性质、亲水性、表面可及性、柔韧性等,预测Blo t 21蛋白的B抗原表位和T抗原表位,同时利用B...目的预测热带无爪螨主要变应原Blo t 21的抗原表位。方法利用DNAStar Protean软件分析热带无爪螨主要变应原Blo t 21的二级结构和表面特性,如理化性质、亲水性、表面可及性、柔韧性等,预测Blo t 21蛋白的B抗原表位和T抗原表位,同时利用Bepi Pred在线分析预测其可能的B细胞抗原表位。结果 Blo t 21蛋白的二级结构以α螺旋为主,存在7个潜在的B抗原表位位点,可能的B抗原表位区域有:2-11,19-28,35-54,55-70,72-83,96-112,123-129氨基酸残基或其附近。含有8个潜在的T细胞抗原表位区域:13-17,22-31,37-46,51-64,69-75,80-84,95-99,102-105氨基酸残基或其附近。结论应用Protean软件和Bepi Pred在线预测了热带无爪螨主要变应原Blo t 21的抗原表位,为进一步研究Blo t 21变应原的结构与功能,研制针对热带螨的预防性和治疗性疫苗、开发相应的诊断试剂盒奠定了基础。展开更多
Cherry Blossoms Blooming In Advance提前盛开的樱花The blooming of cheny blossoms marks the arrival of spring.Down the ages,records of when the trees bloom have been kept by people.The data is so detailed and goes back ...Cherry Blossoms Blooming In Advance提前盛开的樱花The blooming of cheny blossoms marks the arrival of spring.Down the ages,records of when the trees bloom have been kept by people.The data is so detailed and goes back so far,and it,s allowed scientists to speculate(推测)Japan's climate data in centuries past.For the last 200 years,flowerings have generally come earlier and earlier caused,scientists think,by climate change.展开更多
文摘利用DNAStar Protean软件对热带无爪螨主要致敏原Blo t 5的二级结构和表面特性进行分析,如理化性质、亲水性、表面可及性、可塑性等,预测Blo t 5蛋白的B抗原表位和T抗原表位。实验结果表明,Blo t 5蛋白的二级结构以α螺旋为主,存在6个潜在的B抗原表位位点,可能的B抗原表位区域有:18-31,39-48,56-77,86-101,105-112,117-133氨基酸残基或其附近。含有7个潜在的T细胞抗原表位区域:32-37,40-44,57-65,70-79,86-95,100-104,115-120氨基酸残基或其附近。笔者应用Protean软件预测了热带无爪螨主要致敏原Blo t 5的抗原表位,为进一步研究Blo t 5致敏原的结构与功能,研制针对热带螨的预防性和治疗性疫苗、开发相应的诊断试剂盒奠定了基础。
基金Research supported by NNSF of China (No. 19131080) and NEDF of China
文摘In this paper we study multilinear oscillatory singular integrals with rough kernel and give a criterion of certain boundedness for this kind of operator
基金supported by the National Natural Science Foundation of China(Grant Nos.10271015&60272042)the 973 Project of China(Grant No.G19990751).
文摘Two pointwise estimates relating the maximal multilinear singular integral operators and some classical maximal operators are established. These pointwise estimates imply the rearrangement estimate and the BLO(Rn) estimate for the maximal multilinear singular integral operators.
文摘Correlated radio-optical variations on intraday timescales have been observed （e.g. in BLO 0716＋714） and such radio intraday variability is suggested to have an intrinsic origin. Recently, multi-wavelength observations, simultaneous at radio, mm-submm, optical and hard X-rays, of 0716＋714, show that during a period of intraday/interday variations at radio and mm wavelengths, the apparent brightness temperature of the source exceeded the Compton-limit （-10^12 K） by 2-4 orders of magnitude, but no Compton catastrophe （or no high luminosity of inverse-Compton radiation） was detected. It is also found that the intraday/interday variations at mm-submm wavelengths are consistent with the evolutionary behavior of a standard synchrotron source and for the intraday/interday variations at centimeter wavelengths opacity effects can play a significant role, which is consistent with the interpretation suggested previously by Qian et al. Thus the apparent high brightness temperatures may probably be explained in terms of Doppler boosting effects due to bulk relativistic motion of the source. We will argue a scenario to simulate the correlations between the radio and optical variations on intraday timescales observed in BLO 0716＋714 in terms of a relativistic shock propagating through a jet with a dual structure.
基金Project 10671062 is supported by NSF of China,Project 11071065 is supported by NSF of ChinaProject 20094306110004 supported by RFDP of high education of China and Supported by the Program for Science and Technology Research Team in Higher Educational Institutions of Hunan Province
文摘In this paper, we extend Hu and Zhang＇s results in [2] to different case.
文摘目的预测热带无爪螨主要变应原Blo t 21的抗原表位。方法利用DNAStar Protean软件分析热带无爪螨主要变应原Blo t 21的二级结构和表面特性,如理化性质、亲水性、表面可及性、柔韧性等,预测Blo t 21蛋白的B抗原表位和T抗原表位,同时利用Bepi Pred在线分析预测其可能的B细胞抗原表位。结果 Blo t 21蛋白的二级结构以α螺旋为主,存在7个潜在的B抗原表位位点,可能的B抗原表位区域有:2-11,19-28,35-54,55-70,72-83,96-112,123-129氨基酸残基或其附近。含有8个潜在的T细胞抗原表位区域:13-17,22-31,37-46,51-64,69-75,80-84,95-99,102-105氨基酸残基或其附近。结论应用Protean软件和Bepi Pred在线预测了热带无爪螨主要变应原Blo t 21的抗原表位,为进一步研究Blo t 21变应原的结构与功能,研制针对热带螨的预防性和治疗性疫苗、开发相应的诊断试剂盒奠定了基础。
文摘Cherry Blossoms Blooming In Advance提前盛开的樱花The blooming of cheny blossoms marks the arrival of spring.Down the ages,records of when the trees bloom have been kept by people.The data is so detailed and goes back so far,and it,s allowed scientists to speculate(推测)Japan's climate data in centuries past.For the last 200 years,flowerings have generally come earlier and earlier caused,scientists think,by climate change.
