A straightforward electrochemical reduction of benzo[b]thiophene 1,1-dioxides with HFIP as the hydrogen donor has been reported in an undivided cell under metal-free conditions.Moreover,the tolerance of various functi...A straightforward electrochemical reduction of benzo[b]thiophene 1,1-dioxides with HFIP as the hydrogen donor has been reported in an undivided cell under metal-free conditions.Moreover,the tolerance of various functional groups and scaled-up experiments showed the practicability and potential applications of this methodology.展开更多
Benzo[b]thiophene fused compounds with a unique active heterocyclic skeleton have wide applications in the fields of medicinal chemistry,organic synthesis,and organic functional materials,which resulted in rapid devel...Benzo[b]thiophene fused compounds with a unique active heterocyclic skeleton have wide applications in the fields of medicinal chemistry,organic synthesis,and organic functional materials,which resulted in rapid development of many efficient methods for the construction of benzo[b]thiophenefused heterocycles in recent years.Among these methods,the domino reaction of benzo[b]thiophene derivatives is a practical and powerful synthetic route to access benzo[b]thiophene-fused heterocycles by virtue of the particularity of sulfur atom.This review summarizes the latest developments in the construction of benzo[b]thiophene-fused heterocycles by ring formation at the C2-C3-position of benzo[b]thiophene derivatives in the past decade.Additionally,this review is divided into four parts according to the four kinds of benzo[b]thiophene derivatives used,including thioaurone,thioisatin,substituted benzo[b]thiophene,and azadiene.展开更多
A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, 1H nuclear magnetic resonance（IH NMR） and high...A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, 1H nuclear magnetic resonance（IH NMR） and high-resolution mass spectrometry（HRMS）. The bioassay tests indicate that their insecticidal activities were weak to moderate. Antibacterial tests indicate that some of the compounds showed favourable activity in vitro against Physa- lospora piricola, Alternaria solani, Cercospora arachidicola, Gibberella sanbinetti and Phytophthora infestans at a dosage of 50 mg/L.展开更多
基金supported by the National Natural Science Foundation of China(21801152 and 21572110)We thank the Youth Innovation Science and Technology Plan of Colleges and Universities in Shandong Province(2021KJ076).
文摘A straightforward electrochemical reduction of benzo[b]thiophene 1,1-dioxides with HFIP as the hydrogen donor has been reported in an undivided cell under metal-free conditions.Moreover,the tolerance of various functional groups and scaled-up experiments showed the practicability and potential applications of this methodology.
基金financially supported by the National Natural Science Foundation of China(Nos.21403154 and 22003045)the Natural Science Foundation of Tianjin(No.13JCYBJC38700)the Tianjin Municipal Education Commission(No.2018KJ137)。
文摘Benzo[b]thiophene fused compounds with a unique active heterocyclic skeleton have wide applications in the fields of medicinal chemistry,organic synthesis,and organic functional materials,which resulted in rapid development of many efficient methods for the construction of benzo[b]thiophenefused heterocycles in recent years.Among these methods,the domino reaction of benzo[b]thiophene derivatives is a practical and powerful synthetic route to access benzo[b]thiophene-fused heterocycles by virtue of the particularity of sulfur atom.This review summarizes the latest developments in the construction of benzo[b]thiophene-fused heterocycles by ring formation at the C2-C3-position of benzo[b]thiophene derivatives in the past decade.Additionally,this review is divided into four parts according to the four kinds of benzo[b]thiophene derivatives used,including thioaurone,thioisatin,substituted benzo[b]thiophene,and azadiene.
基金Supported by the National Natural Science Foundation of China（No.20872069）, the National Basic Research Program of China（No.2010CB 126106）, the National Key Technologies R＆D Program of China（No.2011BAE06B05）, the Tianjin Natural Science Foundation, China（No. 11JCYBJC08600） and the Fund of State Key Laboratory of Elemento-Organic Chemistry, China.
文摘A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, 1H nuclear magnetic resonance（IH NMR） and high-resolution mass spectrometry（HRMS）. The bioassay tests indicate that their insecticidal activities were weak to moderate. Antibacterial tests indicate that some of the compounds showed favourable activity in vitro against Physa- lospora piricola, Alternaria solani, Cercospora arachidicola, Gibberella sanbinetti and Phytophthora infestans at a dosage of 50 mg/L.
