The genus Zanthoxylum (Rutaceae) is comprised of about 50 species in China.Zanthoxylum dissitum Hems-ley, locally called 'Shanpipa', has been used to treat pains in the loin,limbs and arthritis in Chinese folk...The genus Zanthoxylum (Rutaceae) is comprised of about 50 species in China.Zanthoxylum dissitum Hems-ley, locally called 'Shanpipa', has been used to treat pains in the loin,limbs and arthritis in Chinese folk medicine. Our previous study reported the isolation andidentification of five quinoline alkaloids . In this continuing study on the chemcial constituentsof Zanthoxylum dissitum Hemsley, a phenylalanine derivative was obtained .展开更多
目的:对小蓟的化学成分进行研究。方法:运用硅胶柱层析、Sephadex LH-20柱层析等手段进行分离,运用UV、1HNMR、13CNMR、MS等波谱方法进行结构鉴定。结果:共分离鉴定了6个化合物,分别为乙酸橙酰胺(auran-tiam ide acetate,1),loliolide(...目的:对小蓟的化学成分进行研究。方法:运用硅胶柱层析、Sephadex LH-20柱层析等手段进行分离,运用UV、1HNMR、13CNMR、MS等波谱方法进行结构鉴定。结果:共分离鉴定了6个化合物,分别为乙酸橙酰胺(auran-tiam ide acetate,1),loliolide(2),刺槐素(acacetin,3),蒙花苷(linarin,4),洋芹素-7-O-β-D-葡萄糖醛酸丁酯(ap igen in-7-O-β-D-butylglucuron ide,5),β-胡萝卜苷(β-daucosterol,6)。结论:化合物1为首次从蓟属植物中分离得到,化合物2、5、6首次从小蓟中分离得到。展开更多
AIM:To study the chemical constituents of the style of Zea mays L.METHODS:The constituents were isolated and purified by various chromatographic methods,and their structures were identified by spectroscopic analysis.R...AIM:To study the chemical constituents of the style of Zea mays L.METHODS:The constituents were isolated and purified by various chromatographic methods,and their structures were identified by spectroscopic analysis.RESULTS:Nine compounds were obtained and their structures were elucidated as β-sitosterol(1),chrysoeriol(2),chrysoeriol 6-C-β-boivino-pyranosyl(3),chrysoeriol 6-C-β-boivinopyranosyl-7-O-β-glucopyranoside(4),ax-4″-OH-3’-methoxy-maysin(5),p-coumaric acid(6),vanillic acid(7),aurantiamide acetate(8),pseudolario acid E(9).CONCLUSION:Compounds 2,6-9 were isolated from the style of Zea mays L.for the first time.展开更多
目的：对采自南中国海海域的群海绵（A gelas mauritiana）的化学成分进行研究。方法采用硅胶色谱柱、Sephadex L H-20凝胶色谱柱、高效液相色谱等色谱方法，对 A gelas mauritiana正丁醇萃取物进行分离纯化；应用现代波谱技术对化合物...目的：对采自南中国海海域的群海绵（A gelas mauritiana）的化学成分进行研究。方法采用硅胶色谱柱、Sephadex L H-20凝胶色谱柱、高效液相色谱等色谱方法，对 A gelas mauritiana正丁醇萃取物进行分离纯化；应用现代波谱技术对化合物进行化学结构鉴定；用M T T法对化合物进行体外人肺癌细胞株A549细胞生长抑制活性测试。结果共分离得到8个化合物，分别鉴定为：agelasine A （1）、agelasine B （2）、epi-agelasine C （3）、（-）agelasine D （4）、agelasine E （5）、agelasine F （6）、（-）ageloxime D （7）、aurantiamide acetate （8）。体外活性筛选中，这些化合物对A549显示出不同程度的生长抑制活性，化合物1∽3的活性与阳性对照阿霉素相近。结论化合物1、2、4、5、6、8为首次从该种海绵中分离得到。首次选用A549对化合物1～7的活性进行评价，化合物2、3的显著生长抑制活性为进一步深入研究提供了依据。展开更多
文摘The genus Zanthoxylum (Rutaceae) is comprised of about 50 species in China.Zanthoxylum dissitum Hems-ley, locally called 'Shanpipa', has been used to treat pains in the loin,limbs and arthritis in Chinese folk medicine. Our previous study reported the isolation andidentification of five quinoline alkaloids . In this continuing study on the chemcial constituentsof Zanthoxylum dissitum Hemsley, a phenylalanine derivative was obtained .
文摘目的:对小蓟的化学成分进行研究。方法:运用硅胶柱层析、Sephadex LH-20柱层析等手段进行分离,运用UV、1HNMR、13CNMR、MS等波谱方法进行结构鉴定。结果:共分离鉴定了6个化合物,分别为乙酸橙酰胺(auran-tiam ide acetate,1),loliolide(2),刺槐素(acacetin,3),蒙花苷(linarin,4),洋芹素-7-O-β-D-葡萄糖醛酸丁酯(ap igen in-7-O-β-D-butylglucuron ide,5),β-胡萝卜苷(β-daucosterol,6)。结论:化合物1为首次从蓟属植物中分离得到,化合物2、5、6首次从小蓟中分离得到。
文摘AIM:To study the chemical constituents of the style of Zea mays L.METHODS:The constituents were isolated and purified by various chromatographic methods,and their structures were identified by spectroscopic analysis.RESULTS:Nine compounds were obtained and their structures were elucidated as β-sitosterol(1),chrysoeriol(2),chrysoeriol 6-C-β-boivino-pyranosyl(3),chrysoeriol 6-C-β-boivinopyranosyl-7-O-β-glucopyranoside(4),ax-4″-OH-3’-methoxy-maysin(5),p-coumaric acid(6),vanillic acid(7),aurantiamide acetate(8),pseudolario acid E(9).CONCLUSION:Compounds 2,6-9 were isolated from the style of Zea mays L.for the first time.
文摘目的：对采自南中国海海域的群海绵（A gelas mauritiana）的化学成分进行研究。方法采用硅胶色谱柱、Sephadex L H-20凝胶色谱柱、高效液相色谱等色谱方法，对 A gelas mauritiana正丁醇萃取物进行分离纯化；应用现代波谱技术对化合物进行化学结构鉴定；用M T T法对化合物进行体外人肺癌细胞株A549细胞生长抑制活性测试。结果共分离得到8个化合物，分别鉴定为：agelasine A （1）、agelasine B （2）、epi-agelasine C （3）、（-）agelasine D （4）、agelasine E （5）、agelasine F （6）、（-）ageloxime D （7）、aurantiamide acetate （8）。体外活性筛选中，这些化合物对A549显示出不同程度的生长抑制活性，化合物1∽3的活性与阳性对照阿霉素相近。结论化合物1、2、4、5、6、8为首次从该种海绵中分离得到。首次选用A549对化合物1～7的活性进行评价，化合物2、3的显著生长抑制活性为进一步深入研究提供了依据。
