Prior to his initial diagnosis, a 21-year-old male had been experiencing facial acne for two years and had been treated by a doctor in private practice. The patient visited our department because the clinical manifest...Prior to his initial diagnosis, a 21-year-old male had been experiencing facial acne for two years and had been treated by a doctor in private practice. The patient visited our department because the clinical manifestations of mandibular acne did not improve. At the time of initial examination, telangiectasia (TE), post-inflammatory erythema (PIE), post-inflammatory hyperpigmentation (PIH), atrophic scars (ASs), and a hypertrophic scar (HS) with induration were observed on the right neck. We diagnosed this as an acne vulgaris complication. HS lesions were topically treated by injecting triamcinolone acetonide, and the patient was prescribed 8.1 g/day of oral Saireito (Japanese herb). Adapalene benzoyl peroxide gel and topical tacrolimus hydrate ointment were used to treat PIE and TE. Both HSs and PIE improved;however, TE and AS did not improve. Currently, the patient is under observation. We consider this to be a very rare concurrent occurrence of diverse complications of acne vulgaris, and present the following case study.展开更多
目的:分析超脉冲点阵CO_(2)激光联合自体脂肪移植对痤疮萎缩性瘢痕的治疗作用。方法:按照随机数字表法将2019年10月-2020年10月笔者医院收治的86例痤疮萎缩性瘢痕患者分为对照组与观察组,每组43例。对照组采用超脉冲点阵CO_(2)激光进行...目的:分析超脉冲点阵CO_(2)激光联合自体脂肪移植对痤疮萎缩性瘢痕的治疗作用。方法:按照随机数字表法将2019年10月-2020年10月笔者医院收治的86例痤疮萎缩性瘢痕患者分为对照组与观察组,每组43例。对照组采用超脉冲点阵CO_(2)激光进行治疗,观察组采用超脉冲点阵CO_(2)激光联合自体脂肪移植进行治疗。治疗1周后,观察两组治疗效果、结痂时间、结痂脱落时间、愈合时间、皮肤生理指标[经皮水分丢失(Transepidermal waterloss,TEWL)、红斑指数(Erythema index,EI)、角质层含水量]及不良反应情况。结果:观察组的总有效率明显高于对照组[95.35%(41/43) vs 76.74%(33/43)],差异有统计学意义(P<0.05)。观察组结痂时间、结痂脱落时间及愈合时间均明显短于对照组,差异有统计学意义(P<0.05)。观察组的TEWL、EI明显低于对照组,角质层含水量明显高于对照组,差异有统计学意义(P<0.05)。两组均未发生严重不良反应。结论:超脉冲点阵CO_(2)激光联合自体脂肪移植对痤疮萎缩性瘢痕具有很好的治疗作用,能够明显改善皮肤功能。展开更多
文摘Prior to his initial diagnosis, a 21-year-old male had been experiencing facial acne for two years and had been treated by a doctor in private practice. The patient visited our department because the clinical manifestations of mandibular acne did not improve. At the time of initial examination, telangiectasia (TE), post-inflammatory erythema (PIE), post-inflammatory hyperpigmentation (PIH), atrophic scars (ASs), and a hypertrophic scar (HS) with induration were observed on the right neck. We diagnosed this as an acne vulgaris complication. HS lesions were topically treated by injecting triamcinolone acetonide, and the patient was prescribed 8.1 g/day of oral Saireito (Japanese herb). Adapalene benzoyl peroxide gel and topical tacrolimus hydrate ointment were used to treat PIE and TE. Both HSs and PIE improved;however, TE and AS did not improve. Currently, the patient is under observation. We consider this to be a very rare concurrent occurrence of diverse complications of acne vulgaris, and present the following case study.
文摘目的:分析超脉冲点阵CO_(2)激光联合自体脂肪移植对痤疮萎缩性瘢痕的治疗作用。方法:按照随机数字表法将2019年10月-2020年10月笔者医院收治的86例痤疮萎缩性瘢痕患者分为对照组与观察组,每组43例。对照组采用超脉冲点阵CO_(2)激光进行治疗,观察组采用超脉冲点阵CO_(2)激光联合自体脂肪移植进行治疗。治疗1周后,观察两组治疗效果、结痂时间、结痂脱落时间、愈合时间、皮肤生理指标[经皮水分丢失(Transepidermal waterloss,TEWL)、红斑指数(Erythema index,EI)、角质层含水量]及不良反应情况。结果:观察组的总有效率明显高于对照组[95.35%(41/43) vs 76.74%(33/43)],差异有统计学意义(P<0.05)。观察组结痂时间、结痂脱落时间及愈合时间均明显短于对照组,差异有统计学意义(P<0.05)。观察组的TEWL、EI明显低于对照组,角质层含水量明显高于对照组,差异有统计学意义(P<0.05)。两组均未发生严重不良反应。结论:超脉冲点阵CO_(2)激光联合自体脂肪移植对痤疮萎缩性瘢痕具有很好的治疗作用,能够明显改善皮肤功能。
