Frozen shoulder is a common disease which causes significant morbidity. Despite over a hundred years of treating this condition the definition, diagnosis, pathology and most efficacious treatments are still largely un...Frozen shoulder is a common disease which causes significant morbidity. Despite over a hundred years of treating this condition the definition, diagnosis, pathology and most efficacious treatments are still largely unclear. This systematic review of current treatments for frozen shoulder reviews the evidence base behind physiotherapy, both oral and intra articular steroid, hydrodilatation, manipulation under anaesthesia and arthroscopic capsular release. Key areas in which future research could be directed are identified, in particular with regard to the increasing role of arthroscopic capsular release as a treatment.展开更多
Treatment options for meniscal tears fall into three broad categories;non-operative,meniscectomy or meniscal repair.Selecting the most appropriate treatment for a given patient involves both patient factors(e.g.,age,c...Treatment options for meniscal tears fall into three broad categories;non-operative,meniscectomy or meniscal repair.Selecting the most appropriate treatment for a given patient involves both patient factors(e.g.,age,co-morbidities and compliance)and tear characteristics(e.g.,location of tear/age/reducibility of tear).There is evidence suggesting that degenerative tears in older patients without mechanical symptoms can be effectively treated non-operatively with a structured physical therapy programme as a first line.Even if these patients later require meniscectomy they will still achieve similar functional outcomes than if they had initially been treated surgically.Partial meniscectomy is suitable for symptomatic tears not amenable to repair,and can still preserve meniscal function especially when the peripheral meniscal rim is intact.Meniscal repair shows 80%success at 2 years and is more suitable in younger patients with reducible tears that are peripheral(e.g.,nearer the capsular attachment)and horizontal or longitudinal in nature.However,careful patient selection and repair technique is required with good compliance to post-operative rehabilitation,which often consists of bracing and non-weight bearing for 4-6 wk.展开更多
目的:相关临床研究表明关节镜清理联合透明质酸钠治疗老年膝骨关节炎具有积极的作用,然而其有效性及安全性尚未完全明确,缺乏充足的循证依据。文章以此对关节镜清理联合透明质酸钠治疗老年膝骨关节炎的临床疗效进行Meta分析。方法:计算...目的:相关临床研究表明关节镜清理联合透明质酸钠治疗老年膝骨关节炎具有积极的作用,然而其有效性及安全性尚未完全明确,缺乏充足的循证依据。文章以此对关节镜清理联合透明质酸钠治疗老年膝骨关节炎的临床疗效进行Meta分析。方法:计算机检索PubMed、Cochrane Library、Web of science、EMbase、维普、中国知网、CBM、万方数据库以及百度学术资源系统中关节镜清理联合透明质酸钠注射治疗老年膝骨关节炎的随机对照试验,检索时间2016-01-01/2020-10-30。由2名研究者独立完成检索和筛选文献,利用Cochrane风险偏倚评估工具对纳入研究进行质量评价,提取数据资料并运用RevMan 5.3软件进行Meta分析。结果:①共纳入12项随机对照试验,包括老年单侧膝骨关节炎患者1072例。②Meta分析结果显示,对比单纯关节镜清理术,联合透明质酸钠注射治疗老年膝骨关节炎具有更高的临床总有效率(RR=1.24,95%CI:1.15-1.33,P<0.00001),在Lysholm评分(SMD=9.80,95%CI:8.09-11.51,P<0.00001)和目测类比评分(MD=-1.19,95%CI:-1.58至-0.80,P<0.00001)上更有优势,而且膝关节液白细胞介素1水平(MD=-9.95,95%CI:-11.31至-8.59,P<0.00001)、白细胞介素6水平(MD=-33.68,95%CI:-42.42至-24.93,P<0.00001)和肿瘤坏死因子α水平(MD=-84.72,95%CI:-91.49至-77.95,P<0.00001)更低,两组不良反应发生率无显著差异(RR=0.60,95%CI:0.30-1.18,P=0.14)。结论:与单纯关节镜清理术相比,关节镜清理联合透明质酸钠治疗老年膝骨关节炎具有更高的临床疗效,具体体现在缓解关节疼痛、改善膝关节功能和降低炎性因子水平方面,但未来仍需更多质量高、样本量大的随机对照试验加以验证。展开更多
文摘Frozen shoulder is a common disease which causes significant morbidity. Despite over a hundred years of treating this condition the definition, diagnosis, pathology and most efficacious treatments are still largely unclear. This systematic review of current treatments for frozen shoulder reviews the evidence base behind physiotherapy, both oral and intra articular steroid, hydrodilatation, manipulation under anaesthesia and arthroscopic capsular release. Key areas in which future research could be directed are identified, in particular with regard to the increasing role of arthroscopic capsular release as a treatment.
文摘Treatment options for meniscal tears fall into three broad categories;non-operative,meniscectomy or meniscal repair.Selecting the most appropriate treatment for a given patient involves both patient factors(e.g.,age,co-morbidities and compliance)and tear characteristics(e.g.,location of tear/age/reducibility of tear).There is evidence suggesting that degenerative tears in older patients without mechanical symptoms can be effectively treated non-operatively with a structured physical therapy programme as a first line.Even if these patients later require meniscectomy they will still achieve similar functional outcomes than if they had initially been treated surgically.Partial meniscectomy is suitable for symptomatic tears not amenable to repair,and can still preserve meniscal function especially when the peripheral meniscal rim is intact.Meniscal repair shows 80%success at 2 years and is more suitable in younger patients with reducible tears that are peripheral(e.g.,nearer the capsular attachment)and horizontal or longitudinal in nature.However,careful patient selection and repair technique is required with good compliance to post-operative rehabilitation,which often consists of bracing and non-weight bearing for 4-6 wk.
文摘目的:相关临床研究表明关节镜清理联合透明质酸钠治疗老年膝骨关节炎具有积极的作用,然而其有效性及安全性尚未完全明确,缺乏充足的循证依据。文章以此对关节镜清理联合透明质酸钠治疗老年膝骨关节炎的临床疗效进行Meta分析。方法:计算机检索PubMed、Cochrane Library、Web of science、EMbase、维普、中国知网、CBM、万方数据库以及百度学术资源系统中关节镜清理联合透明质酸钠注射治疗老年膝骨关节炎的随机对照试验,检索时间2016-01-01/2020-10-30。由2名研究者独立完成检索和筛选文献,利用Cochrane风险偏倚评估工具对纳入研究进行质量评价,提取数据资料并运用RevMan 5.3软件进行Meta分析。结果:①共纳入12项随机对照试验,包括老年单侧膝骨关节炎患者1072例。②Meta分析结果显示,对比单纯关节镜清理术,联合透明质酸钠注射治疗老年膝骨关节炎具有更高的临床总有效率(RR=1.24,95%CI:1.15-1.33,P<0.00001),在Lysholm评分(SMD=9.80,95%CI:8.09-11.51,P<0.00001)和目测类比评分(MD=-1.19,95%CI:-1.58至-0.80,P<0.00001)上更有优势,而且膝关节液白细胞介素1水平(MD=-9.95,95%CI:-11.31至-8.59,P<0.00001)、白细胞介素6水平(MD=-33.68,95%CI:-42.42至-24.93,P<0.00001)和肿瘤坏死因子α水平(MD=-84.72,95%CI:-91.49至-77.95,P<0.00001)更低,两组不良反应发生率无显著差异(RR=0.60,95%CI:0.30-1.18,P=0.14)。结论:与单纯关节镜清理术相比,关节镜清理联合透明质酸钠治疗老年膝骨关节炎具有更高的临床疗效,具体体现在缓解关节疼痛、改善膝关节功能和降低炎性因子水平方面,但未来仍需更多质量高、样本量大的随机对照试验加以验证。
