Seventeen compounds were isolated from aerial part of Bupleurum marginatum Wall. ex DC. by column chromatography method, and thirteen compounds were identified by means of physical and spectral data. These compounds w...Seventeen compounds were isolated from aerial part of Bupleurum marginatum Wall. ex DC. by column chromatography method, and thirteen compounds were identified by means of physical and spectral data. These compounds were quercetin (Ⅰ), stigmasta-7, 25-dien-3-ol (Ⅱ), 7-stigmasten-3β-ol (Ⅲ), cholest-7-en-3β-ol (Ⅳ), α-spinasterol (Ⅴ), octacosanoic acid (Ⅵ), β-sitosterol (Ⅶ), daucosterol (Ⅷ), isorhamnetin (Ⅸ), quercetin-3-O-β-D-glucoside (Ⅹ), rutin (Ⅺ), saikochromone A (Ⅻ) and adonitol (). Compound Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ, Ⅸ, Ⅹ and were firstly isolated from this species.展开更多
目的：比较分析穿山龙地上部分和根茎总皂苷抗炎活性,为穿山龙地上部分的开发利用提供实验依据。方法：采用小鼠耳廓肿胀实验、小鼠棉球肉芽肿法和小鼠腹腔液渗出法对同时、同地采收的穿山龙地上部分和根茎水提取物的抗炎作用进行比较...目的：比较分析穿山龙地上部分和根茎总皂苷抗炎活性,为穿山龙地上部分的开发利用提供实验依据。方法：采用小鼠耳廓肿胀实验、小鼠棉球肉芽肿法和小鼠腹腔液渗出法对同时、同地采收的穿山龙地上部分和根茎水提取物的抗炎作用进行比较研究。结果：穿山龙地上部分总皂苷（to-tal saponins of aerial part of Dioscorea nipponica Makino,TSAPDN）可明显减轻小鼠耳肿胀,降低肉芽肿的重量,减少小鼠腹腔液的渗出,与空白对照组比较差异有显著性（P〈0.05-0.001）;与根茎总皂苷（total saponins of the radicular of Dioscorea nipponica Makino,TSRDN）比较差异无显著性（P〉0.05）。结论：TSAPDN有显著的抗炎作用,其抗炎活性与根茎相近。展开更多
文摘Seventeen compounds were isolated from aerial part of Bupleurum marginatum Wall. ex DC. by column chromatography method, and thirteen compounds were identified by means of physical and spectral data. These compounds were quercetin (Ⅰ), stigmasta-7, 25-dien-3-ol (Ⅱ), 7-stigmasten-3β-ol (Ⅲ), cholest-7-en-3β-ol (Ⅳ), α-spinasterol (Ⅴ), octacosanoic acid (Ⅵ), β-sitosterol (Ⅶ), daucosterol (Ⅷ), isorhamnetin (Ⅸ), quercetin-3-O-β-D-glucoside (Ⅹ), rutin (Ⅺ), saikochromone A (Ⅻ) and adonitol (). Compound Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ, Ⅸ, Ⅹ and were firstly isolated from this species.
文摘目的：比较分析穿山龙地上部分和根茎总皂苷抗炎活性,为穿山龙地上部分的开发利用提供实验依据。方法：采用小鼠耳廓肿胀实验、小鼠棉球肉芽肿法和小鼠腹腔液渗出法对同时、同地采收的穿山龙地上部分和根茎水提取物的抗炎作用进行比较研究。结果：穿山龙地上部分总皂苷（to-tal saponins of aerial part of Dioscorea nipponica Makino,TSAPDN）可明显减轻小鼠耳肿胀,降低肉芽肿的重量,减少小鼠腹腔液的渗出,与空白对照组比较差异有显著性（P〈0.05-0.001）;与根茎总皂苷（total saponins of the radicular of Dioscorea nipponica Makino,TSRDN）比较差异无显著性（P〉0.05）。结论：TSAPDN有显著的抗炎作用,其抗炎活性与根茎相近。
